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T17918Thalidomide-O-amido-PEG2-C2-NH2 TFAE3 Ligase Ligand-Linker Conjugates 24 TFA;Cereblon Ligand-Linker
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17918产 地:中国大陆
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T17916Pomalidomide-PEG4-C2-NH2Cereblon Ligand-Linker Conjugates 8;E3 Ligase Ligand-Linker Conjugates 22
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.
价 格:¥电议型 号:T17916产 地:中国大陆
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T17913(S,R,S)-AHPC-PEG2-N3VHL Ligand-Linker Conjugates 6;E3 ligase Ligand-Linker Conjugates 13;VH032-PEG2-
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.
价 格:¥电议型 号:T17913产 地:中国大陆
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T17909(S,R,S)-AHPC-PEG3-N3E3 ligase Ligand-Linker Conjugates 12;VHL Ligand-Linker Conjugates 8;VH032-PEG3-
(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17909产 地:中国大陆
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T15189Thalidomide-O-amido-C4-N3Cereblon Ligand-Linker Conjugates 4;E3 ligase Ligand-Linker Conjugates 18
Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T15189产 地:中国大陆
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T11419O6BTG-octylglucosideO6BTG-octylglucoside,Glucose-conjugated MGMT inhibitor,
O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 10 nM in HeLa S3 cells?and 32 nM in vitro (cell extracts).?
价 格:¥电议型 号:T11419产 地:美洲
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T80249Epsilon-V1-2, Cys-conjugated;化合物 Epsilon-V1-2, Cys-conjugatedEpsilon-V1-2, Cys-conjugated
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally perturbing εPKC´s interaction with its anchoring protein, εRACK. The peptide includes a cysteine residue at its C-terminus, facilitating the formation of potential disulfide bonds with carrier proteins. Pyroglutamyl formation can occur spontaneously at the N-terminus if glutamine
价 格:¥电议型 号:T80249产 地:中国大陆
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T77861XMT-1519 conjugate-1;化合物 XMT-1519 conjugate-1XMT-1519 conjugate-1
XMT-1519 conjugate-1 (compound 31) serves as a linker for the HER-2 monoclonal antibody XMT-1519, facilitating the synthesis of antibody-drug conjugates (ADCs) to enhance antitumor activity [1].
价 格:¥电议型 号:T77861产 地:中国大陆
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T7760Thalidomide-O-amido-C3-NH2 TFA;化合物Thalidomide-O-amido-C3-NH2 TFACereblon Ligand-Linker Conjugates 16
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T7760产 地:中国大陆
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T7759Thalidomide-O-amido-C4-NH2 TFA;化合物T7759E3 ligase Ligand-Linker Conjugates 19 TFA|||Cereblon Ligand-L
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized E3 ligase ligand-linker conjugate.
价 格:¥电议型 号:T7759产 地:中国大陆
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T7758Thalidomide-O-amido-PEG3-C2-NH2 TFA;化合物T7758E3 ligase Ligand-Linker Conjugates 14 TFA|||Cereblon Lig
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T7758产 地:中国大陆
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T7757Cereblon Ligand -Linker Conjugates 2 TFA化合物 T7757Cereblon Ligand -Linker Conjugates 2 TFA|||Cereblon
Cereblon Ligand -Linker Conjugates 2 TFA is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T7757产 地:中国大陆
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T75383Anti-α-Tubulin Antibody, AF555 conjugate;化合物 Anti-α-Tubulin Antibody, AF555 conjugateAnti-α-Tubulin
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the specific detection of tubulin (Ex/Em: 554/567 nm) [1].
价 格:¥电议型 号:T75383产 地:中国大陆
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T74975Zn-DPA-maytansinoid conjugate 1;化合物 Zn-DPA-maytansinoid conjugate 1Zn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid conjugate 1, a small molecule-based immune checkpoint-targeting maytansinoid conjugate, effectively induces sustained tumor growth regression and transforms the tumor microenvironment (TME) into an "inflamed hot tumor" [1].
价 格:¥电议型 号:T74975产 地:中国大陆
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T74877GalNAc unconjugated/naked Fitusiran;化合物 GalNAc unconjugated/naked FitusiranGalNAc unconjugated/naked
GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran increases thrombin generation and has the potential for the research of the hemophilia [1] .
价 格:¥电议型 号:T74877产 地:中国大陆
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T74876GalNAc unconjugated/naked Inclisiran;化合物 GalNAc unconjugated/naked InclisiranGalNAc unconjugated/nak
Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hyperlipidemia and cardiovascular disease (CVD) [1].
价 格:¥电议型 号:T74876产 地:中国大陆
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T74571TSPO Ligand-Linker Conjugates 1;化合物 TSPO Ligand-Linker Conjugates 1TSPO Ligand-Linker Conjugates 1
TSPO Ligand-Linker Conjugates 1, comprising a translocator protein (TSPO) ligand and a linker, is instrumental in synthesizing mitochondria-targeting autophagy-targeting chimera (AUTAC). This compound binds TSPO on the outer mitochondrial membrane (OMM), facilitating the degradation of malfunctioning mitochondria and proteins through mitophagy, thereby enhancing mitochondrial function. It holds potential applications in research related to mitochondrial dysfunction, encompassing neurodegenerativ
价 格:¥电议型 号:T74571产 地:中国大陆
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T40140Zanamivir-Cholesterol Conjugate;Zanamivir-Cholesterol ConjugateZanamivir-Cholesterol Conjugate
Zanamivir-cholesterol conjugate is an extended-duration neuraminidase inhibitor highly effective against drug-resistant influenza strains.
价 格:¥电议型 号:T40140产 地:中国大陆
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T39703ATRA-biotin;ATRA-biotinATRA-biotin|||Biotin-ATRA-conjugate;ATRA-biotin|||Biotin-ATRA-conjugate
ATRA-biotin is a biotin-conjugated form of all-trans retinoic acid (ATRA). It is utilized for the purpose of tracking ATRA within cells or specific tissues.
价 格:¥电议型 号:T39703产 地:中国大陆
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T39629BRD4 ligand-Linker Conjugate 1;BRD4 ligand-Linker Conjugate 1BRD4 ligand-Linker Conjugate 1;BRD4 lig
BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules utilized for targeted protein degradation.
价 格:¥电议型 号:T39629产 地:中国大陆