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T39609cIAP1 Ligand-Linker Conjugates 16;cIAP1 Ligand-Linker Conjugates 16cIAP1 Ligand-Linker Conjugates 16
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
价 格:¥电议型 号:T39609产 地:中国大陆
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T39375Thalidomide-O-amido-PEG2-C2-NH2;Thalidomide-O-amido-PEG2-C2-NH2Cereblon Ligand-Linker Conjugates 10
Thalidomide-O-amido-PEG2-C2-NH2, which combines an E3 ligase ligand with a linker, serves as an immunomodulator for cancer treatment.
价 格:¥电议型 号:T39375产 地:中国大陆
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T39361Thalidomide-O-amido-C6-NH2;Thalidomide-O-amido-C6-NH2E3LigaseLigand-LinkerConjugates25|||Cereblon Li
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11) is a Thalidomide-based synthetic E3 ligase ligand-linker conjugate, comprising of a cereblon ligand and a linker. This compound is employed in the production of PROTACs (proteolysis-targeting chimeras).
价 格:¥电议型 号:T39361产 地:中国大陆
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T37797Coumarin-Quinone Conjugate;Coumarin-Quinone ConjugateCoumarin-Quinone Conjugate
Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductases. It has been used to measure the kinetic parameters of apoptosis-inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1).
价 格:¥电议型 号:T37797产 地:中国大陆
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T372709(E),11(E)-12-nitro Conjugated Linoleic Acid;9(E),11(E)-12-nitro Conjugated Linoleic Acid9(E),11(E)-
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.
价 格:¥电议型 号:T37270产 地:中国大陆
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T36853Phalloidin-Tetramethylrhodamine Conjugate;Phalloidin-Tetramethylrhodamine ConjugatePhalloidin-Tetram
Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin. It can be used to localize actin filaments in living or fixed cells, as well as for visualizing individual actin filaments in vitro.
价 格:¥电议型 号:T36853产 地:中国大陆
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T36852Phalloidin-AMCA Conjugate;Phalloidin-AMCA ConjugatePhalloidin-AMCA Conjugate
Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin). It consists of aminomethylcoumarin (AMCA; ex/em max = 350/450 nm) conjugated with phalloidin , a mycotoxin that binds F-actin. Phalloidin-AMCA conjugate is used in fixed and permeabilized tissue sections, cell cultures, or cell-free experiments.
价 格:¥电议型 号:T36852产 地:中国大陆
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T36314Wortmannin-Rapamycin Conjugate;Wortmannin-Rapamycin ConjugateWortmannin-Rapamycin Conjugate
Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer. Wortmannin is a potent inhibitor of PI3K enzymes, while rapamycin blocks mTOR Complex 1 TORC1. Wortmannin-rapamycin conjugate consists of analogs of 17-hydroxy wortmannin and rapamycin conjugated via a prodrug linker. Hydrolysis of the prodrug linker in vivo releases the inhibitors. The wortmannin-rapamycin conjugate inhibits the growth of HT-29 colon tumors and A498 renal tumors in
价 格:¥电议型 号:T36314产 地:中国大陆
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T35980Bilirubin Conjugate (sodium salt);Bilirubin Conjugate (sodium salt)Bilirubin Conjugate (sodium salt)
Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives.
价 格:¥电议型 号:T35980产 地:中国大陆
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T358549(Z),11(E)-Conjugated Linoleic Acid (sodium salt);9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)9
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co
价 格:¥电议型 号:T35854产 地:中国大陆
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T34788Taurolithocholic acid;化合物 T34788Lithocholyltaurine|||Lithocholic acid taurine conjugate;Lithocholylt
Taurolithocholic acid is a cholagogue and choleretic.
价 格:¥电议型 号:T34788产 地:中国大陆
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T31964Glycolithocholic acid;甘氨石胆酸Lithocholic acid glycine conjugate|||Lithocholylglycine;Lithocholic acid
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
价 格:¥电议型 号:T31964产 地:中国大陆
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T27200DOX?NOP1 HCl;化合物 T27200doxorubicin-NOP1 conjugate|||doxorubicin-NOP1 HCl|||DOX?NOP1 Hydrochloride;do
DOX?NOP1 is a molecular hybrid covalently joining doxorubicin (DOX) and NOP1. DOX?NOP1 showed similar increased toxicity toward resistant cancer cells and, in addition, lower cardiotoxicity than DOX.
价 格:¥电议型 号:T27200产 地:中国大陆
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T23950Dacomitinib metabolite M2;化合物 T23950Dacomitinib cysteine conjugate|||UNII-SOA52D3NLL;Dacomitinib cys
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
价 格:¥电议型 号:T23950产 地:中国大陆
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T21009Conjugated linoleic acid;化合物 T21009Conjugated linoleic acid
Conjugated linoleic acid, a naturally occurring fatty acid, is present in ruminant meat and dairy products and is produced by a bio-hydrogenation process in the rumen. In this case, the predominant isomer formed is 9cis, 11trans.
价 格:¥电议型 号:T21009产 地:中国大陆
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T19988Conjugated Estrogen sodium;化合物 T19988Conjugated estrogens|||Conest|||HSDB 3076|||Kestrin|||Estrogens
Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estrogen. Conjugated estrogens tablet is also used to treat symptoms of breast and prostate cancer that have spread through the body in men and women.
价 格:¥电议型 号:T19988产 地:中国大陆
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T18873VHL Ligand-Linker Conjugates 17;化合物 T18873VHL Ligand-Linker Conjugates 17
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1].
价 格:¥电议型 号:T18873产 地:中国大陆
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T18872(S,R,S)-AHPC-PEG5-COOH;化合物 T18872VH032-PEG5-COOH|||E3 Ligase Ligand-Linker Conjugates 58|||VHL Ligan
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1].
价 格:¥电议型 号:T18872产 地:中国大陆
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T18867Val-Cit-PAB-MMAE;化合物Val-Cit-PAB-MMAEDrug-Linker Conjugates for ADC|||inhibit|||Val-Cit-PAB-MMAE|||In
Val-Cit-PAB-MMAE is a?drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE?a potent?mitotic?inhibitor by inhibiting tubulin polymerization[1].
价 格:¥电议型 号:T18867产 地:中国大陆
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T18826Thalidomide-O-PEG2-propargyl;化合物 T18826E3 ligase Ligand-Linker Conjugates 32;E3 ligase Ligand-Linker
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].
价 格:¥电议型 号:T18826产 地:中国大陆