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T61990Topoisomerase I/II inhibitor 3；化合物 Topoisomerase I/II inhibitor 3Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell proliferation, invasion and migration, and induce apoptosis . Topoisomerase I/II inhibitor 3 has research value in liver cancer.
价 格：￥电议型 号：T61990产 地：中国大陆
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T61982Human carbonic anhydrase II-IN-2；化合物 Human carbonic anhydrase II-IN-2Human carbonic anhydrase II-IN-
Human carbonic anhydrase II-IN-24 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor. Human carbonic anhydrase II-IN-24 shows K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively.
价 格：￥电议型 号：T61982产 地：中国大陆
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T61981Human carbonic anhydrase II-IN-1；化合物 Human carbonic anhydrase II-IN-1Human carbonic anhydrase II-IN-
Human carbonic anhydrase II-IN-1 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor. Human carbonic anhydrase II-IN-1 shows Kis of 4.4 nM, 9.2 nM, 480.2 nM and 14.7 nM for hCA II, I, IV and IX, respectively. Human carbonic anhydrase II-IN-1 can be used for glaucoma research.
价 格：￥电议型 号：T61981产 地：中国大陆
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T61980Carbonic anhydrase inhibitor 8；化合物 Carbonic anhydrase inhibitor 8Carbonic anhydrase inhibitor 8
Carbonic anhydrase inhibitor 8 (compound R-13) is a potent human carbonic anhydrase (hCA). Carbonic anhydrase inhibitor 8 shows K i values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively.
价 格：￥电议型 号：T61980产 地：中国大陆
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T61952Carbonic anhydrase inhibitor 13；化合物 Carbonic anhydrase inhibitor 13Carbonic anhydrase inhibitor 13
Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).
价 格：￥电议型 号：T61952产 地：中国大陆
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T61937DNA Gyrase-IN-3；化合物 DNA Gyrase-IN-3DNA Gyrase-IN-3
DNA Gyrase-IN-3 (Compound 28) is an inhibitor of bacterial DNA gyrase B. The IC50 of DNA Gyrase-IN-3 inhibits Escherichia coli DNA rotatase is 5.41-15.64 μM. DNA Gyrase-IN-3 shows anti-tuberculosis and antibacterial activity.
价 格：￥电议型 号：T61937产 地：中国大陆
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T61842Carbonic anhydrase inhibitor 14；化合物 Carbonic anhydrase inhibitor 14Carbonic anhydrase inhibitor 14
Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM. Furthermore, Carbonic anhydrase inhibitor 14 demonstrates significant antitumor activity [1].
价 格：￥电议型 号：T61842产 地：中国大陆
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T61829Carbonic anhydrase inhibitor 4；化合物 Carbonic anhydrase inhibitor 4Carbonic anhydrase inhibitor 4
Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1].
价 格：￥电议型 号：T61829产 地：中国大陆
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T6182Tirofiban；替罗非班L700462|||Aggrastat|||MK383；L700462|||Aggrastat|||替罗非班|||MK383
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
价 格：￥电议型 号：T6182产 地：中国大陆
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T61717Topoisomerase I inhibitor 4；化合物 Topoisomerase I inhibitor 4Topoisomerase I inhibitor 4
Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity. It effectively inhibits the proliferation of various cancer cell lines including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
价 格：￥电议型 号：T61717产 地：中国大陆
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T61683Antiparasitic agent-9；化合物 Antiparasitic agent-9Antiparasitic agent-9
Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1].
价 格：￥电议型 号：T61683产 地：中国大陆
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T61641Antiparasitic agent-5；化合物 Antiparasitic agent-5Antiparasitic agent-5
Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects on HepG2 cells with a CC50 value of 6.78 μM [1].
价 格：￥电议型 号：T61641产 地：中国大陆
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T6163Salirasib；法尼基硫代水杨酸Farnesyl Thiosalicylic Acid|||S-Farnesylthiosalicylic acid|||FTS；沙利雷塞|||法尼基硫代水杨酸||
Salirasib (Farnesyl Thiosalicylic Acid)(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.
价 格：￥电议型 号：T6163产 地：中国大陆
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T61538Antiparasitic agent-10；化合物 Antiparasitic agent-10Antiparasitic agent-10
Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Schistosoma mansoni. As a result, this compound holds significant potential for utilization in Schistosomiasis research as a viable treatment option [1].
价 格：￥电议型 号：T61538产 地：中国大陆
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T61501Topoisomerase I inhibitor 5；化合物 Topoisomerase I inhibitor 5Topoisomerase I inhibitor 5
Topoisomerase I inhibitor 5 is an efficient inhibitor of topoisomerase I, with an IC50 value. It effectively disrupts DNA and inhibits the activity of topoisomerase I. Moreover, it can induce apoptosis in MCF-7 cells and arrest the cell cycle at the G1 phase. Topoisomerase I inhibitor 5 also exhibits potency in reversing P-gp-mediated resistance to Adriamycin [1].
价 格：￥电议型 号：T61501产 地：中国大陆
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T61431Topoisomerase IIα-IN-4；化合物 Topoisomerase IIα-IN-4Topoisomerase IIα-IN-4
Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive inhibitor of human DNA topoisomerase II, specifically inhibiting TopoIIα with an IC50 value of 3.8 μM and TopoIIβ with an IC50 value of 10.1 μM. It demonstrates significant efficacy in inducing apoptosis and arresting the cell cycle in HepG2 cells. Moreover, Topoisomerase IIα-IN-4 exhibits robust antitumor effects against various human cancer cell lines, making it a valuable compound for cancer research [1].
价 格：￥电议型 号：T61431产 地：中国大陆
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T61283Topoisomerase II inhibitor 3；化合物 Topoisomerase II inhibitor 3Topoisomerase II inhibitor 3
Topoisomerase II inhibitor 3 (Compound 6 h) is an acridone derivative that acts as a Type II DNA topoisomerase (topo II) inhibitor. It specifically inhibits the topo IIα/β subtypes, with an IC50 value of 0.17 μM for topo IIα and 0.23 μM for topo IIβ. This compound elicits significant DNA damage and induces apoptosis by triggering the loss of mitochondrial membrane potential [1].
价 格：￥电议型 号：T61283产 地：中国大陆
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T61245Antiparasitic agent-7；化合物 Antiparasitic agent-7Antiparasitic agent-7
Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity against HepG2 cells with a CC50 value of 10.61 μM [1].
价 格：￥电议型 号：T61245产 地：中国大陆
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T61221Antiparasitic agent-8；化合物 Antiparasitic agent-8Antiparasitic agent-8
Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1].
价 格：￥电议型 号：T61221产 地：中国大陆
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T61160Antiparasitic agent-2；化合物 Antiparasitic agent-2Antiparasitic agent-2
Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it demonstrates moderate cytotoxicity against HepG2 cells with a CC50 of 26.79 μM [1].
价 格：￥电议型 号：T61160产 地：中国大陆
