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T36761KRAS inhibitor-10；KRAS inhibitor-10KRAS inhibitor-10
KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer research, specifically in pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer. KRAS inhibitor-10 is classified as a tetrahydroisoquinoline compound. Its inhibitory properties provide valuable insights and potential therapeutic applications in the field of
价 格：￥电议型 号：T36761产 地：中国大陆
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T36647Trastuzumab emtansine；曲妥珠单抗-美坦新偶联物Trastuzumab emtansine
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that combines the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of DM1, a microtubule-inhibitory derivative of maytansine. This compound is utilized in the investigation of advanced breast cancer[1][2].
价 格：￥电议型 号：T36647产 地：中国大陆
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T36646Trastuzumab deruxtecan；德曲妥珠单抗DS-8201a|||VRN-101099|||DS 8201|||T-DXd；DS-8201a|||VRN-101099|||DS 8201
Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gastric cancers.
价 格：￥电议型 号：T36646产 地：中国大陆
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T36642RAS/RAS-RAF-IN-1；RAS/RAS-RAF-IN-1RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1].
价 格：￥电议型 号：T36642产 地：中国大陆
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T36641RAS inhibitor Abd-7；RAS inhibitor Abd-7RAS inhibitor Abd-7
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders RAS-effector interactions and suppresses endogenous RAS-dependent signaling. Additionally, RAS inhibitor Abd-7 disrupts the PPI of different mutant KRAS proteins with PI3K, CRAF, RALGDS, as well as NRAS Q61H and HRAS G12V[1].
价 格：￥电议型 号：T36641产 地：中国大陆
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T3628Madrasin；化合物MadrasinDDD00107587；DDD00107587
Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
价 格：￥电议型 号：T3628产 地：中国大陆
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T36256LC-2；化合物LC-2LC 2|||PROTAC KRASG12C Degrader-LC-2|||LC2；LC 2|||PROTAC KRASG12C Degrader-LC-2|||LC2
LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is a PROTAC that covalently binds KRAS G12C with MRTX849 and recruits the E3 ligase, VH, to induce a rapid and sustained degradation of KRAS G12C. LC-2 inhibits MAPK signaling in pure and heterozygous KRAS G12C cell lines.
价 格：￥电议型 号：T36256产 地：中国大陆
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T36057Diallyl Tetrasulfide；Diallyl TetrasulfideICD-1585；ICD-1585
Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.[1],[2],[3],[4] It is active against the bacteria S. aureus and methicillin-resistant S. aureus (MRSA; MICs = 0.5 and 2 mg/L, respectively), as well as the fungi C. albicans, C. krusei, C. glabrata, A. niger, A. flavus, and A. fumigatus (MICs = 0.5, 4, 2, 1, 2, and 4 mg/L, respectively).[1] It reduces cadmium-ind
价 格：￥电议型 号：T36057产 地：中国大陆
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T36018Phosphodiesterase 4 Inhibitor；Phosphodiesterase 4 InhibitorPhosphodiesterase 4 Inhibitor
Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
价 格：￥电议型 号：T36018产 地：中国大陆
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T35994Erastin2；Erastin2Erastin2；Erastin2
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM).[2] It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 or deferoxamine . [1] Erastin2 also induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 µM), an effect that can be blocked by the reducing agent β-merc
价 格：￥电议型 号：T35994产 地：中国大陆
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T35616Migrastatin；MigrastatinMigrastatin
Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic acetylcholine receptors (Kis = >200, 200, 31, 43, and >200 μM, respectively) and inhibits calcium mobilization induced by carbamoylcholine in SK-N-SH cells (IC50= 28 μM), as well as in primary rat bladder smooth muscle cells.1Migrastatin inhibits the migration of EC17 esophageal cancer cells in a wound healing assay (IC50= 10 μg/ml) and 4T1 mouse mam
价 格：￥电议型 号：T35616产 地：中国大陆
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T34263Rastim 30 dkv；化合物 T34263Rastim 30 dkv
Rastim 30 dkv is a plant growth regulator based on bensoline.
价 格：￥电议型 号：T34263产 地：中国大陆
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T3370Hederacoside C；常春藤苷CKalopanaxsaponin B|||Hederasaponin C；常春藤苷C|||Kalopanaxsaponin B|||Hederasaponin
Hederacoside C (Hederasaponin C) is expectorant for Cold and cough relief, Bronchitis.
价 格：￥电议型 号：T3370产 地：中国大陆
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T3359Aprotinin；抑肽酶Bovine Pancreatic Trypsin Inhibitor|||Traskolan|||Antilysin；抑酶肽|||抑肽酶|||Bovine Pancreat
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator, and tissue and leukocytic proteinases.
价 格：￥电议型 号：T3359产 地：中国大陆
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T3345Hederasaponin B；刺五加叶中Eleutheroside M|||Hederacoside B；常春藤皂苷B|||Eleutheroside M|||刺五加叶中|||Hederacosid
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.
价 格：￥电议型 号：T3345产 地：中国大陆
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T33024Lycomarasmine；化合物 T33024Lycomarasmine
Lycomarasmine is a bioactive chemical.
价 格：￥电议型 号：T33024产 地：中国大陆
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T32923Lucerastat；化合物 T32923NBDGJ；NBDGJ
Lucerastat is a very effective and selective α-gal A (α-D-galactosidase) inhibitor for the treatment of lipid storage diseases and Fabry disease.
价 格：￥电议型 号：T32923产 地：中国大陆
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T32419KRAS4b-PDEδ stabilizer C19；化合物 T32419KRAS4b-PDEδ stabilizer C19
KRAS4b-PDEδ stabilizer C19 is a stabilizer of the KRAS4b-PDEδ complex which decreases the proliferation of colorectal cancer cells, and increases apoptosis via decreased activation of oncogenic KRAS4b signaling.
价 格：￥电议型 号：T32419产 地：中国大陆
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T32182Iopydone；化合物 T32182NSC 135284|||NSC135284|||NSC-135284|||Hytrast|||Iopydonum；NSC 135284|||NSC135284|
Iopydone is an iodinated contrast dye.
价 格：￥电议型 号：T32182产 地：中国大陆
