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T5S0814Berberine hydrogen sulphateBerberine hydrogen sulphate,Berberine Sulfate,Umbellatine Sulfate
Berberine sulfate, an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
价 格:¥电议型 号:T5S0814产 地:美洲
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T5S1679Acetylcimigenol 3-O-alpha-L-arabinopyranAcetylcimigenol 3-O-alpha-L-arabinopyran
产品用于生物细胞实验
价 格:¥电议型 号:T5S1679产 地:美洲
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T5S1981alpha-Cyperonealpha-Cyperone,(+)-α-Cyperone,α-Cyperone
1. Alpha-Cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. Alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA
价 格:¥电议型 号:T5S1981产 地:美洲
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T6112DoxercalciferolDoxercalciferol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
价 格:¥电议型 号:T6112产 地:美洲
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T6127Rucaparib PhosphateRucaparib Phosphate,PF-01367338 phosphate,AG-014699 phosphate
Rucaparib is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:美洲
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T6128PHA-665752PHA-665752,PHA665752,PHA 665752
PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.
价 格:¥电议型 号:T6128产 地:美洲
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T6206PHA-767491PHA-767491,PHA767491,PHA 767491
PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
价 格:¥电议型 号:T6206产 地:美洲
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T6272Fosbretabulin DisodiumFosbretabulin Disodium,CA 4P,Combretastatin A4 disodium phosphate
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium inhibits the polymerization of tubulin (IC50: 2.4 μ
价 格:¥电议型 号:T6272产 地:美洲
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T6501Fludarabine PhosphateFludarabine Phosphate,F-ara-A (NSC 312887) Phosphate,fludara Phosphate
Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylat
价 格:¥电议型 号:T6501产 地:美洲
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T8789N-Acetyl-L-tryptophan;N-乙酰-L-色氨酸N-acetyltryptophan;N-acetyltryptophan|||N-乙酰-L-色氨酸
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
价 格:¥电议型 号:T8789产 地:中国大陆
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T87141-Stearoyl-sn-glycero-3-phosphocholine;1-硬脂酰-SN-甘油-3-磷酰胆碱1-stearoyl-lysophosphatidylcholine|||L-ALPH
1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) is a chemical used in lipid metabolism studies
价 格:¥电议型 号:T8714产 地:中国大陆
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T8589(±)-Amiflamine;4-(2-氨基丙基)-N,N,3-三甲基苯胺4-(dimethylamino)-alpha|||Amiflamine|||2-dimethylphenethylamine
(±)-Amiflamine (2-dimethylphenethylamine) is an inhibitor of reversible MAO-A.
价 格:¥电议型 号:T8589产 地:中国大陆
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T8557N-terminally acetylated Leu-enkephalin;化合物T8557N-terminally acetylated Leu-enkephalin
Leu-enkephalin, an endogenous peptide consisting of five amino acids, functions as an agonist at opioid receptors. The N-terminally acetylated form of this compound is known as N-terminally acetylated Leu-enkephalin.
价 格:¥电议型 号:T8557产 地:中国大陆
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T83910S1PL-IN-31;化合物 S1PL-IN-31Sphingosine-1-Phosphate Lyase Inhibitor 31|||S1PL Inhibitor 31|||S1P Lyase
S1PL-IN-31 is a dual-function chemical compound acting as an inhibitor of sphingosine-1-phosphate (S1P) lyase with an IC50 value of 210 nM and as an antagonist of the Smoothened (Smo) receptor with an IC50 of 440 nM. Demonstrating therapeutic potential, this compound, at a dosage of 2 mg/kg per day, effectively mitigates cervical and thoracic lymphocyte infiltration and neuromuscular weakness in rats suffering from experimental autoimmune encephalomyelitis (EAE), a condition triggered by the MOG
价 格:¥电议型 号:T83910产 地:中国大陆
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T83908DXR Inhibitor 11a (free acid);化合物 DXR Inhibitor 11a (free acid)1-Deoxy-D-Xylulose-5-phosphate Reduct
DXR inhibitor 11a, with an IC50 of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrating an IC50 of 0.37 ?M.
价 格:¥电议型 号:T83908产 地:中国大陆
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T83885DXR Inhibitor 11a sodium;化合物 DXR Inhibitor 11a sodium1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
DXR inhibitor 11a, with an IC50 value of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum´s growth in isolated human erythrocytes, with an IC50 of 0.37 ?M.
价 格:¥电议型 号:T83885产 地:中国大陆
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T83880C18 Ceramide-1-phosphate (d18:1/18:0) ammonium;化合物 C18 Ceramide-1-phosphate (d18:1/18:0) ammoniumCer
C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (HUVECs) at concentrations of 0.5 to 5 ?M. It exhibits elevated levels in CFPAC-1 pancreatic ductal adenocarcinoma cells compared to pancreatic cancer stem cells, and its myocardial concentration is heightened in Langendorff isolated perfused mouse hearts under an ex vivo ischemia
价 格:¥电议型 号:T83880产 地:中国大陆
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T838791-Arachidoyl Lysophosphatidic Acid sodium;化合物 1-Arachidoyl Lysophosphatidic Acid sodium1-Arachidoyl
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 ?M, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 ?M, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferat
价 格:¥电议型 号:T83879产 地:中国大陆
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T83840Uridine-5’-O-(3-thiotriphosphate) sodium;化合物 Uridine-5’-O-(3-thiotriphosphate) sodiumUTP-γ-S;UTP-γ-S
Uridine-5´-O-(3-thiotriphosphate) (UTP-γ-S) is a hydrolysis-resistant UTP derivative and an agonist of the purinergic P2Y2 receptor. It effectively induces inositol phosphate formation in 1321N1 astrocytoma cells harboring the human P2Y2 receptor (EC50 = 240 nM) and stimulates chloride secretion in a dose-dependent manner in primary nasal epithelial cells from cystic fibrosis patients. Moreover, UTP-γ-S prompts vasoconstriction in isolated human coronary arteries (EC50 = 25.1 ?M).
价 格:¥电议型 号:T83840产 地:中国大陆
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T83839Uridine 5’-methylenediphosphate sodium;化合物 Uridine 5’-methylenediphosphate sodiumα,β-methylene UDP||
Uridine 5’-methylenediphosphate (UMP-CP), a hydrolytically stable derivative of UDP and agonist of the purinergic P2Y14 receptor, exhibits selective inhibition of cAMP production in cells expressing human P2Y14 compared to those expressing human P2Y6, with EC50 values of 11 nM and 339 nM, respectively.
价 格:¥电议型 号:T83839产 地:中国大陆