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T9687MAGL-IN-4Monoacylglycerol lipase,CB1,lipase,monoacylglycerol,CB2,Inhibitor,inhibit,BBB,barrier,MAGLI
MAGL-IN-4 is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
价 格:¥电议型 号:T9687产 地:中国大陆
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T9229Pim-1/2 kinase inhibitor 12,4 Thiazolidinedione, 5 p methoxybenzylidene ,2,4Thiazolidinedione, 5pmet
Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27 Kip1. Pim-1/2 kinase inhibitor 1 can be used in the cancer research, especially prostate cancer [1].
价 格:¥电议型 号:T9229产 地:中国大陆
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T8357SB-200646electrophysiological,5-HT Receptor,SNC,Serotonin Receptor,Inhibitor,antipsychotic,inhibit,5
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
价 格:¥电议型 号:T8357产 地:中国大陆
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TN1362AfzelinPTEN,MMAC1,Afzelin,Phosphatase and tensin homolog,inhibit,Autophagy,Inhibitor,Bacterial,Mitoc
Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1.
价 格:¥电议型 号:TN1362产 地:中国大陆
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TP1250LAcetyl-PHF6 amide acetate(878663-43-5 freebase)AcetylPHF6 amide acetate(878663435 freebase),Acetyl P
Acetyl-PHF6 amide acetate is a tau derived hexapeptide.
价 格:¥电议型 号:TP1250L产 地:中国大陆
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TP1508LN-Acetyl-α-Endorphin acetate(88264-63-5 free base)N Acetyl α Endorphin acetate(88264 63 5 free base)
N-Acetyl-α-Endorphin acetate is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.
价 格:¥电议型 号:TP1508L产 地:中国大陆
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T7058Selisistat S-enantiomerSelisistat Senantiomer,Sirtuin,(S)-Selisistat,Selisistat S enantiomer,inhibit
Selisistat S-enantiomer is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.
价 格:¥电议型 号:T7058产 地:中国大陆
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T8184Fucosterolpoly ADP ribose polymerase,Fucosterol,Inhibitor,inhibit,Endogenous Metabolite,PARP
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
价 格:¥电议型 号:T8184产 地:中国大陆
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TP1295Angiotensin I (human, mouse, rat)inhibit,Inhibitor,Angiotensin I (human, mouse, rat)
Angiotensin 1 (Human) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex to promote sodium retention by the kidneys.
价 格:¥电议型 号:TP1295产 地:中国大陆
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TQ0207SulforaphaneInhibitor,Keap1-Nrf2,Apoptosis,Sulforaphane,Histone deacetylases,inhibit,HDAC
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
价 格:¥电议型 号:TQ0207产 地:中国大陆
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TN1545D-TyrosineTyrosinase,D-amino,Inhibitor,D Tyrosine,acid,disassociates,biofilm,melanin,D-Tyrosine,DTyr
D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth.
价 格:¥电议型 号:TN1545产 地:中国大陆
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TN260112-O-Methylcarnosic acid12 O Methylcarnosic acid,5α-reductase,Inhibitor,5 alpha Reductase,inhibit,12
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells.12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly
价 格:¥电议型 号:TN2601产 地:中国大陆
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T7953BpV(HOpic)MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),s
bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
价 格:¥电议型 号:T7953产 地:中国大陆
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T8898GranilinFungal,sesquiterpene,Bacterial,inhibit,Inhibitor,bactericide,Granilin,fungicide,lactone
Graniline is a natural product.
价 格:¥电议型 号:T8898产 地:中国大陆
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T7027EURYCOMANONEinhibit,EURYCOMANONE,Phosphodiesterase (PDE),Inhibitor
Eurycomanone is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell proliferation in a dose-dependent manner at concentrations ranging from 5 to 20 μg/ml.
价 格:¥电议型 号:T7027产 地:中国大陆
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TP1199LUrotensin I acetate (83930-33-0 Free base)Urotensin I acetate (83930330 Free base),Urotensin I aceta
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
价 格:¥电议型 号:TP1199L产 地:中国大陆
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T6S1665IrisflorentinNOS,Irisflorentin,inhibit,Inhibitor,iNOS,Nitric oxide synthases,macrophages,inflammator
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
价 格:¥电议型 号:T6S1665产 地:中国大陆
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TP1116LKinetensin acetate(103131-69-7 free base)Kinetensin acetate(103131697 free base),Kinetensin acetate(
Kinetensin acetate is isolated from pepsin-treated human plasma.Kinetensin acetate is a neurotensin-like peptide.
价 格:¥电议型 号:TP1116L产 地:中国大陆
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TP1419LHAEGTFT acetate(926018-95-3 free base)HAEGTFT acetate(926018 95 3 free base),HAEGTFT acetate(9260189
HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.
价 格:¥电议型 号:TP1419L产 地:中国大陆
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T9833Opiranserin hydrochlorideVVZ 149,analgesic,postoperative,VVZ-149,5-hydroxytryptamine Receptor,5-HT R
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50=0.87 μM). It is development as an injectable agent for the treatment of postoperative pain.
价 格:¥电议型 号:T9833产 地:中国大陆