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T18361MMAE-SMCC;化合物 T18361MMAE-SMCC
MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs.
价 格:¥电议型 号:T18361产 地:中国大陆
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T18332MC-VC-PABC-Aur0101;化合物 T18332MCVCPABCAur0101|||MC-VC-PABC-Aur-0101|||MC VC PABC Aur0101|||MC-VC-PABC
MC-VC-PABC-Aur0101 is a potent anticancer drug-linker conjugate designed for Antibody-Drug Conjugates (ADCs), comprising Aur0101, an auristatin microtubule inhibitor, connected through the MC-VC-PABC linker to enhance antitumor efficacy.
价 格:¥电议型 号:T18332产 地:中国大陆
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T18331MC-VC-PABC-DNA31;化合物 T18331MC-VC-PABC-DNA31
MC-VC-PABC-DNA31 is a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC) that demonstrates potent antitumor activity. It employs DNA31, an effective inhibitor of RNA polymerase, connected through the MC-VC-PABC ADC linker.
价 格:¥电议型 号:T18331产 地:中国大陆
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T18330MC-Val-Cit-PAB-vinblastine;化合物 T18330MC-Val-Cit-PAB-vinblastine
MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker.
价 格:¥电议型 号:T18330产 地:中国大陆
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T18329MC-VC(S)-PABQ-Tubulysin M;化合物 T18329MC-Val-Cit-PAB-tubulysin5a;MC-Val-Cit-PAB-tubulysin5a
MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18329产 地:中国大陆
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T18328MC-Val-Cit-PAB-rifabutin;化合物 T18328MC-Val-Cit-PAB-rifabutin
MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate designed for antibody-drug conjugates (ADC), featuring the potent antitumor agent rifabutin (a DNA-dependent RNA polymerase inhibitor) connected through the MC-Val-Cit-PAB ADC linker. This configuration endows it with significant antitumor activity.
价 格:¥电议型 号:T18328产 地:中国大陆
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T18327MC-Val-Cit-PAB-Retapamulin;化合物 T18327MC-Val-Cit-PAB-Retapamulin
MC-Val-Cit-PAB-Retapamulin is a drug-linker conjugate for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. This compound utilizes Retapamulin, a ribosome inhibitor, connected through the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18327产 地:中国大陆
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T18326MC-Val-Cit-PAB-MMAF;化合物 T18326MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.
价 格:¥电议型 号:T18326产 地:中国大陆
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T18324MC-Val-Cit-PAB-duocarmycin chloride;化合物 T18324MC-Val-Cit-PAB-duocarmycin;MC-Val-Cit-PAB-duocarmycin
MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
价 格:¥电议型 号:T18324产 地:中国大陆
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T18323MC-Val-Cit-PAB-dimethylDNA31;化合物 T18323MC-Val-Cit-PAB-dimethylDNA31
MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate employed in antibody-drug conjugates (ADCs) that exhibits robust antitumor efficacy. This conjugate utilizes the ADC linker, MC-Val-Cit-PAB, to link to the potent antitumor agent dimethylDNA31. Notably, dimethylDNA31 also demonstrates significant bactericidal activity against both persister and stationary-phase Staphylococcus aureus.
价 格:¥电议型 号:T18323产 地:中国大陆
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T18322MC-Val-Cit-PAB-clindamycin;化合物 T18322MC-Val-Cit-PAB-clindamycin
MC-Val-Cit-PAB-clindamycin is an antibody-drug conjugate (ADC) linker that combines the potent antitumor properties of clindamycin, a protein synthesis inhibitor, with the ADC linker MC-Val-Cit-PAB, to enhance its ability to target and kill cancer cells effectively.
价 格:¥电议型 号:T18322产 地:中国大陆
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T18321Mc-Val-Cit-PAB-Cl;化合物Mc-Val-Cit-PAB-ClMc-Val-Cit-PAB-Cl
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.
价 格:¥电议型 号:T18321产 地:中国大陆
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T18320MC-Val-Cit-PAB-carfilzomib iodide;化合物 T18320MC-Val-Cit-PAB-carfilzomib;MC-Val-Cit-PAB-carfilzomib
MC-Val-Cit-PAB-carfilzomib is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), comprising the irreversible proteasome inhibitor carfilzomib, connected through the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18320产 地:中国大陆
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T18319MC-Val-Cit-PAB-Auristatin E;化合物 T18319MC-Val-Cit-PAB-Auristatin E
MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) linker compound featuring Auristatin E, a potent cytotoxic tubulin modifier, connected through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
价 格:¥电议型 号:T18319产 地:中国大陆
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T18318MC-Val-Ala-PAB-PNP;化合物MC-Val-Ala-PAB-PNPinhibit|||ADC Linkers|||Inhibitor|||MC Val Ala PAB PNP|||Ant
MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18318产 地:中国大陆
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T18317MCC-Modified Daunorubicinol;化合物 T18317MCC-Modified Daunorubicinol
Daunorubicinol, a potent antitumor drug-linker conjugate for antibody-drug conjugate (ADC) applications, utilizes Aur0101 (DNA Topoisomerase II inhibitor) connected through the ADC linker[1].
价 格:¥电议型 号:T18317产 地:中国大陆
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T18316MC-Sq-Cit-PAB-Gefitinib;化合物 T18316MC-Sq-Cit-PAB-Gefitinib
MC-Sq-Cit-PAB-Gefitinib is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Gefitinib—an EGFR tyrosine kinase inhibitor—connected through the MC-Sq-Cit-PAB ADC linker.
价 格:¥电议型 号:T18316产 地:中国大陆
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T18315MC-Sq-Cit-PAB-Dolastatin10;化合物 T18315MC-Sq-Cit-PAB-Dolastatin10
MC-Sq-Cit-PAB-Dolastatin10 is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Dolastatin10 (a tubulin polymerization inhibitor) connected through the MC-Sq-Cit-PAB ADC linker.
价 格:¥电议型 号:T18315产 地:中国大陆
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T18314MC-PEG2-C2-?NHS ester;化合物 T18314MC-PEG2-C2-?NHS ester
MC-PEG2-C2-NHS ester, a noncleavable 2-unit polyethylene glycol (PEG) linker, is employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18314产 地:中国大陆
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T18313Mc-O-Si(di-iso)-Cl;化合物 T18313Mc-O-Si(di-iso)-Cl
Mc-O-Si(di-iso)-Cl is a cleavable ADC linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs) like Gemcitabine-O-Si(di-iso)-O-Mc [1].
价 格:¥电议型 号:T18313产 地:中国大陆