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T11976Mcl1-IN-4;化合物 T11976Mcl1-IN-4
Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).
价 格:¥电议型 号:T11976产 地:中国大陆
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T11975PROTAC Mcl1 degrader-1;化合物 T11975PROTAC Mcl1 degrader-1
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
价 格:¥电议型 号:T11975产 地:中国大陆
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T11974Mcl1-IN-12;化合物 T11974Mcl1-IN-12
Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.
价 格:¥电议型 号:T11974产 地:中国大陆
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T11973Mcl1-IN-11;化合物 T11973Mcl1-IN-11
Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.
价 格:¥电议型 号:T11973产 地:中国大陆
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T11972Mcl-1 inhibitor 3;化合物 T11972Mcl-1 inhibitor 3
Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay).
价 格:¥电议型 号:T11972产 地:中国大陆
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T11971MCL-1/BCL-2-IN-4;化合物 T11971MCL-1/BCL-2-IN-4
MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.
价 格:¥电议型 号:T11971产 地:中国大陆
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T11970MCL-1/BCL-2-IN-3;化合物 T11970MCL-1/BCL-2-IN-3
MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.
价 格:¥电议型 号:T11970产 地:中国大陆
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T11969MCL-1/BCL-2-IN-2;化合物 T11969MCL-1/BCL-2-IN-2
MCL-1/BCL-2-IN-2 is a potent and selective Bcl-2 and Mcl-1 dual inhibitor.
价 格:¥电议型 号:T11969产 地:中国大陆
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T11968MCL-1/BCL-2-IN-1化合物 T11968MCL1/BCL2IN1|||MCL 1/BCL 2 IN 1
MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].
价 格:¥电议型 号:T11968产 地:中国大陆
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T11967Mcl-1 antagonist 1;化合物 T11967Mcl-1 antagonist 1
Mcl-1 antagonist 1 is a Mcl-1 protein antagonist.
价 格:¥电议型 号:T11967产 地:中国大陆
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T11966MCHR1 antagonist 2;化合物MCHR1 antagonist 2MCHR1 antagonist 2
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
价 格:¥电议型 号:T11966产 地:中国大陆
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T11964MCH-1 antagonist 1;化合物 T11964MCH-1 antagonist 1
MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM).
价 格:¥电议型 号:T11964产 地:中国大陆
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T11963MCB-3681;化合物 T11963MCB-3681
MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin´s active substance.
价 格:¥电议型 号:T11963产 地:中国大陆
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T11962MC3482;化合物MC3482MC3482
MC3482 is a specific inhibitor of sirtuin5 (SIRT5).
价 格:¥电议型 号:T11962产 地:中国大陆
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T11917Lys-SMCC-DM1;化合物Lys-SMCC-DM1Lys-Nε-MCC-DM1;Lys-Nε-MCC-DM1
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1.
价 格:¥电议型 号:T11917产 地:中国大陆
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T11662LINT-777;化合物INT-777S-EMCA;S-EMCA
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.
价 格:¥电议型 号:T11662L产 地:中国大陆
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T11662INT-777 R-enantiomer;化合物 T11662S-EMCA R enantiomer;S-EMCA R enantiomer
INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.
价 格:¥电议型 号:T11662产 地:中国大陆
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T11386LGemcabene;化合物GemcabenePD-72953;PD-72953
Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-inflammatory acute-phase protein, C-reactive protei
价 格:¥电议型 号:T11386L产 地:中国大陆
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T11386Gemcabene calcium化合物 T11386PD-72953 calcium
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
价 格:¥电议型 号:T11386产 地:中国大陆
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T11247Etravirine D4;依曲韦林 D4R-165335 D4|||TMC-125 D4;R-165335 D4|||TMC-125 D4|||依曲韦林 D4
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
价 格:¥电议型 号:T11247产 地:中国大陆