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T19450N-desmethyl Enzalutamide；化合物N-desmethyl EnzalutamideN-desmethyl MDV 3100；4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide.
价 格：￥电议型 号：T19450产 地：中国大陆
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T19449N-desmethyl Enzalutamide D6；化合物 T19449N-desmethyl MDV 3100 D6；N-desmethyl MDV 3100 D6
N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
价 格：￥电议型 号：T19449产 地：中国大陆
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T19448N-Desmethyl Clomipramine-d3；化合物 N-Desmethyl Clomipramine-d3Desmethylclomipramine D3 hydrochloride；De
N-Desmethyl Clomipramine-d is the deuterium labeled N-Desmethyl Clomipramine.
价 格：￥电议型 号：T19448产 地：中国大陆
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T1926Sonidegib；化合物SonidegibErismodegib|||NVP-LDE225|||LDE225；Erismodegib|||NVP-LDE225|||LDE225
Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
价 格：￥电议型 号：T1926产 地：中国大陆
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T19214Bredinin aglycone；5-羟基-1H-咪唑-4-甲酰胺5-Hydroxy-1H-imidazole-4-carboxamide|||SM-108；5-Hydroxy-1H-imidazo
Bredinin aglycone (SM-108) is a purine nucleotide analog. It can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogs.
价 格：￥电议型 号：T19214产 地：中国大陆
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T191627-Desmethyl-agomelatine D3；化合物 T191627-Desmethyl-agomelatine D3
7-Desmethyl-agomelatine D3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine.
价 格：￥电议型 号：T19162产 地：中国大陆
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T18856trans-Sulfo-SMCC；化合物 T18856trans-Sulfo-SMCC
trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.
价 格：￥电议型 号：T18856产 地：中国大陆
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T18728Sulfo-SMCC sodium；化合物Sulfo-SMCC sodiumSulfo-SMCC sodium
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable it to specifically react with primary amines and sulfhydryl groups, respectively.
价 格：￥电议型 号：T18728产 地：中国大陆
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T18683SMPT；化合物 T18683SMPT
SMPT, a non-cleavable ADC linker, is utilized in the production of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18683产 地：中国大陆
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T18601Desmethyl-QCA276；化合物 T18601PROTAC BRD4-binding moiety 4；PROTAC BRD4-binding moiety 4
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
价 格：￥电议型 号：T18601产 地：中国大陆
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T18361MMAE-SMCC；化合物 T18361MMAE-SMCC
MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs.
价 格：￥电议型 号：T18361产 地：中国大陆
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T17833DM4-SMCC；化合物 T17833DM4-SMCC
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].
价 格：￥电议型 号：T17833产 地：中国大陆
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T1779SAG；化合物Smoothened AgonistSmoothened Agonist (SAG) HCl|||Smoothened Agonist；Smoothened Agonist (SAG)
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
价 格：￥电议型 号：T1779产 地：中国大陆
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T1735Lurasidone hydrochloride；盐酸鲁拉西酮Lurasidone HCl|||SM-13496 (Hydrochloride)|||SM-13496；Lurasidone HCl||
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antagonist, an antagonist of the adrenergic α2A and α2C receptors, as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder.
价 格：￥电议型 号：T1735产 地：中国大陆
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T17233Vipivotide tetraxetan Linker；化合物 T17233PSMA-617 Linker；PSMA-617 Linker
Vipivotide tetraxetan Linker (PSMA-617 Linker) is a noncleavable peptide linker utilized in the synthesis of Vipivotide tetraxetan (PSMA-617), a ligand instrumental in producing 177Lu-PSMA-617. This radioactive molecule is applied in the treatment of prostate cancer[1].
价 格：￥电议型 号：T17233产 地：中国大陆
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T1704Diosmetin；香叶木素Luteolin 4-methyl ether；Luteolin 4-methyl ether|||香叶木素
Diosmetin (Luteolin 4-methyl ether) has been found to act as a weak TrkB receptor agonist.
价 格：￥电议型 号：T1704产 地：中国大陆
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T16904Smurf1-IN-A01；化合物Smurf1-IN-A01A01；A01
Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
价 格：￥电议型 号：T16904产 地：中国大陆
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T16903SMPH Crosslinker；化合物 T16903SMPH Crosslinker
SMPH Crosslinker is an alkyl/ether-based PROTAC linker utilized for synthesizing PROTACs[1].
价 格：￥电议型 号：T16903产 地：中国大陆
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T16901SMIP004；化合物SMIP004SMIP004
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
价 格：￥电议型 号：T16901产 地：中国大陆
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T16900SMER18；化合物 T16900SMER18
SMER18 is a small molecule enhancer of rapamycin which acts as an mTOR-independent autophagy inducer.
价 格：￥电议型 号：T16900产 地：中国大陆
