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T16899SMCC-DM1;化合物SMCC-DM1DM1-SMCC;DM1-SMCC
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
价 格:¥电议型 号:T16899产 地:中国大陆
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T16897SM-6586;化合物SM-6586SM-6586
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases.
价 格:¥电议型 号:T16897产 地:中国大陆
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T16752Rimacalib化合物 T16752SMP 114
Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).
价 格:¥电议型 号:T16752产 地:中国大陆
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T16748Ridinilazole;化合物RidinilazoleSMT19969;SMT19969
Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L) or vancomycin (MIC90 = 2 mg/L).
价 格:¥电议型 号:T16748产 地:中国大陆
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T16409OSMI-1;化合物OSMI-1OSMI-1
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.
价 格:¥电议型 号:T16409产 地:中国大陆
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T16369O-Desmethyl gefitinib;O-去甲基吉非替尼O-Desmethyl gefitinib
O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 activity.
价 格:¥电议型 号:T16369产 地:中国大陆
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T16290NIK SMI1;化合物NIK SMI1NIK SMI1
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).
价 格:¥电议型 号:T16290产 地:中国大陆
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T1580Desvenlafaxine;去甲文拉法辛WY 45233 Succinate|||O-Desmethylvenlafaxine;去甲文拉法辛|||WY 45233 Succinate|||O-Des
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.
价 格:¥电议型 号:T1580产 地:中国大陆
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T15774Losmiprofen;氯米洛芬Losmiprofen
Losmiprofen is a nonsteroidal compound of antiinflammatory.
价 格:¥电议型 号:T15774产 地:中国大陆
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T15727Sonidegib diphosphate;化合物Erismodegib diphosphateNVP-LDE 225 diphosphate|||Erismodegib diphosphate|||
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively).
价 格:¥电议型 号:T15727产 地:中国大陆
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T15268FAAH-IN-2;4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇O-Desmorpholinopropyl Gefitinib;O-Desmorpholinopropyl Gefitinib
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).
价 格:¥电议型 号:T15268产 地:中国大陆
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T15173DSM265;化合物 DSM265PfSPZ;PfSPZ
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
价 格:¥电议型 号:T15173产 地:中国大陆
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T15161Doxorubicin-SMCC;化合物 T15161Doxorubicin-SMCC
Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15161产 地:中国大陆
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T15117Didesmethyl cariprazine;二去甲基卡利拉嗪Didesmethyl cariprazine
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3/D2 receptor partial agonist of dopamine for the treatment of schizophrenia, bipolar mania, and depression, with a high affinity for d3 and d2 receptors and a moderate affinity for 5-HT 1A receptors.
价 格:¥电议型 号:T15117产 地:中国大陆
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T15100Desmethyl cariprazine;化合物 T15100Desmethyl cariprazine
Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).
价 格:¥电议型 号:T15100产 地:中国大陆
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T15028Cyclopropavir;化合物 T15028MBX-400|||Filociclovir|||ZSM-I-62;MBX-400|||Filociclovir|||ZSM-I-62
Cyclopropavir (Filociclovir; MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 μM to 8 μM).
价 格:¥电议型 号:T15028产 地:中国大陆
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T14923Cefpiramide sodium头孢匹胺钠头孢匹胺钠|||SM-1652|||Wy-44635
Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin. It has a broad spectrum of antibacterial activity.
价 格:¥电议型 号:T14923产 地:中国大陆
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T1472Trospium chloride;曲司氯铵Spasmex|||Sanctura;Spasmex|||Sanctura|||曲司氯铵|||曲司氯胺
Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.
价 格:¥电议型 号:T1472产 地:中国大陆
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T13890SMARCA-BD ligand 1 for Protac dihydrochloride;化合物T13890SMARCA-BD ligand 1 for Protac dihydrochloride
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
价 格:¥电议型 号:T13890产 地:中国大陆
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T13848SMARCA-BD ligand 1 for Protac;化合物SMARCA-BD ligand 1 for ProtacSMARCA-BD ligand 1 for Protac
SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2
价 格:¥电议型 号:T13848产 地:中国大陆