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T11057DM3-SMe;化合物 T11057DM3-SMe
DM3-SMe is a maytansine derivative and tubulin inhibitor. It is a cytotoxic part of antibody-drug conjugates (ADCs) and can bind to antibodies via disulfide bonds or stable thioether bonds. DM3-SMe has high cytotoxic activity in vitro with IC50 of 0.0011 nM.
价 格:¥电议型 号:T11057产 地:中国大陆
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T11047DiosMetin 7-O-β-D-Glucuronide;化合物DiosMetin 7-O-β-D-GlucuronideDiosMetin 7-O-β-D-Glucuronide
DiosMetin 7-O-β-D-Glucuronide is an antioxidant constituent in the fruits of Luffa cylindrical. The consumption of sponge gourds can supply some antioxidant constituents to the human body.
价 格:¥电议型 号:T11047产 地:中国大陆
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T11035diABZI STING agonist-1 (Tautomerism);化合物T11035diABZI STING agonist (Compound 3);diABZI STING agonist
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
价 格:¥电议型 号:T11035产 地:中国大陆
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T11008Desmethylnortriptyline;化合物 T11008Desmethylnortriptyline
Desmethylnortriptyline is a metabolite of nortriptyline. Nortriptyline is a tricyclic antidepressant. It is the main active metabolite of amitriptyline and is used to relieve depressive symptoms.
价 格:¥电议型 号:T11008产 地:中国大陆
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T11007Desmethyl Levofloxacin;化合物 T11007Desmethyl Levofloxacin
Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
价 格:¥电议型 号:T11007产 地:中国大陆
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T11005Desmethyl Celecoxib;塞来昔布杂质3Desmethyl Celecoxib
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM). with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
价 格:¥电议型 号:T11005产 地:中国大陆
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T10976DC4SMe;化合物 T10976DC4SMe
The IC50s of DC4SMe on Ramos, Namalwa and HL60 / s cancer cells were 1.9 nM, 2.9 nM and 1.8 nM, respectively. DC4SMe can be used for targeted therapy of tumors. DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格:¥电议型 号:T10976产 地:中国大陆
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T10975DC44SMe;化合物 T10975DC44SMe
The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格:¥电议型 号:T10975产 地:中国大陆
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T10973DC41SMe;化合物 T10973DC41SMe
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer.
价 格:¥电议型 号:T10973产 地:中国大陆
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T10971DC10SMe;化合物 T10971DC10SMe
DC10SMe is a DNA alkylating agent that can be used in the synthesis of antibody-drug conjugates (ADC). The IC50 of DC10SMe for Ramos, Namalwa and HL60 / s cancer cells were 15 pM, 12 pM and 12 pM, respectively.
价 格:¥电议型 号:T10971产 地:中国大陆
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T10969DC1SMe;化合物 T10969DC1SMe
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s and COLO 205 cancer cells of 22pm, 10pm, 32pm and 250pm, respectively.
价 格:¥电议型 号:T10969产 地:中国大陆
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T101394-Desmethyl Istradefylline;化合物 T101394-Desmethyl Istradefylline
4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson´s disease.
价 格:¥电议型 号:T10139产 地:中国大陆
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T101384-Desmethoxy Omeprazole;埃索美拉唑杂质B4-Desmethoxy Omeprazole
4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).
价 格:¥电议型 号:T10138产 地:中国大陆
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T0991Desipramine hydrochloride盐酸去甲咪嗪NSC-114901|||Desmethylimipramine|||盐酸去甲咪嗪|||JB-8181|||EX-4355|||Norim
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.
价 格:¥电议型 号:T0991产 地:中国大陆
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T0878Diosmin;地奥司明Venosmine|||Diosmil|||Barosmin;Venosmine|||Diosmil|||Barosmin|||地奥司明|||地奥司明(7-芸香糖甙)
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.
价 格:¥电议型 号:T0878产 地:中国大陆
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T06323,4,5-Trimethoxybenzoic acid;3,4,5-三甲氧基苯甲酸Gallic acid trimethyl ether|||Eudesmic acid|||Trimethylgal
3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It also exerts hepatoprotective effects in CCl4-induced rats, specifically by modulating oxidative-nitrosative stress and inflammation.
价 格:¥电议型 号:T0632产 地:中国大陆
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T0572Methyl 3,4,5-trimethoxybenzoate甲氧苄啶杂质HMethyl gallate trimethyl ether|||Methyl EudesMate|||3,4,5-Trim
Methyl 3,4,5-trimethoxybenzoate (Methyl EudesMate) is the intermediate of antibacterial efficiency medicine trimethoprim.
价 格:¥电议型 号:T0572产 地:中国大陆
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T0424Bismuth Subsalicylate;次水杨酸铋Bismuth subsalicylat|||Bismuth(III) salicylate basic|||Bismuth oxysalicyl
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
价 格:¥电议型 号:T0424产 地:中国大陆
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T0414D-MannitolD-甘露糖醇Mannite|||Mannitol|||D-甘露糖醇|||Osmitrol
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
价 格:¥电议型 号:T0414产 地:中国大陆
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T02946α-Methylprednisolone 21-hemisuccinate sodium salt甲强龙琥珀酸钠Asmacortone|||Methylprodnisolone Sodium Suc
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
价 格:¥电议型 号:T0294产 地:中国大陆