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T16101ML-290；化合物ML-290ML-290
ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.
价 格：￥电议型 号：T16101产 地：中国大陆
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T16090LMK-0773 FA；MK-0773 甲酸盐MK-0773 FA (606101-58-0 Free base)；MK-0773 FA (606101-58-0 Free base)
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) is a selective androgen receptor modulator with an IC50 value of 6.6 nM for AR, which can be used for the prevention and treatment of cancer-related muscle wasting.
价 格：￥电议型 号：T16090L产 地：中国大陆
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T15798LX7101；化合物LX7101LX7101
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
价 格：￥电议型 号：T15798产 地：中国大陆
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T15715LAS101057；化合物LAS101057LAS101057
LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma.
价 格：￥电议型 号：T15715产 地：中国大陆
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T15616JNJ-10198409；化合物JNJ-?10198409JNJ-?10198409；3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基苯基胺|||JNJ-?10198409
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
价 格：￥电议型 号：T15616产 地：中国大陆
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T15480HG6-64-1；化合物 T15480HMSL 10017-101-1；HMSL 10017-101-1
HG6-64-1 is a potent and selective inhibitor of B-Raf (IC50: 0.09 μM on B-raf V600E transformed Ba/F3 cells).
价 格：￥电议型 号：T15480产 地：中国大陆
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T15101Devazepide；地伐西匹L-364,718|||MK-329；L-364,718|||地伐西匹|||MK-329
Devazepide is a competitive and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor (IC50s: 81 pM, 45 pM, and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively).
价 格：￥电议型 号：T15101产 地：中国大陆
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T15034Roluperidone；化合物RoluperidoneCYR-101|||MIN-101|||MT-210；CYR-101|||MIN-101|||MT-210
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and σ2).
价 格：￥电议型 号：T15034产 地：中国大陆
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T14992Raxatrigine hydrochloride；化合物 T14992GSK-1014802 hydrochloride|||CNV1014802 (hydrochloride)；GSK-10148
Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.
价 格：￥电议型 号：T14992产 地：中国大陆
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T14989CMPD101；化合物CMPD101CMPD101
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively.
价 格：￥电议型 号：T14989产 地：中国大陆
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T14680BMS-906024；化合物 BMS-906024Osugacestat|||AL-101|||BM-0018；Osugacestat|||AL-101|||BM-0018
BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively.
价 格：￥电议型 号：T14680产 地：中国大陆
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T1447Fenclonine芬克洛宁Fenchlonine|||PCPA|||CP-10188|||芬克洛宁|||4-Chloro-DL-phenylalanine|||DL-4-Chlorophenylal
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to deplete endogenous levels of serotonin.
价 格：￥电议型 号：T1447产 地：中国大陆
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T14133AEOL-10150 pentachloride；化合物AEOL-10150 pentachlorideAEOL-10150 pentachloride
AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant. AEOL-10150 pentachloride also is a superoxide dismutase mimetic. Which protects lungs from radiation-induced injury.
价 格：￥电议型 号：T14133产 地：中国大陆
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T14101Acid-PEG3-C2-Boc；化合物 T14101Acid-PEG3-C2-Boc
Acid-PEG3-C2-Boc is a compound used as a linker in the synthesis of PROTACs to facilitate the degradation of EGFR and the inhibition of mTOR[1][2]. It is classified as a PEG- and alkyl/ether-based PROTAC linker.
价 格：￥电议型 号：T14101产 地：中国大陆
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T14081Enmetazobactam化合物AAI101AAI101
Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor for the treatment of multi-drug resistant gram-negative bacterial infections.
价 格：￥电议型 号：T14081产 地：中国大陆
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T13362XY101；化合物XY101XY101
XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).
价 格：￥电议型 号：T13362产 地：中国大陆
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T13289EHP-101；化合物VCE-004.8VCE-?004.8；VCE-?004.8
EHP-101 (VCE-?004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity.
价 格：￥电议型 号：T13289产 地：中国大陆
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T13247UK-101；化合物UK-101UK101|||UK 101；UK101|||UK 101
UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM. UK-101 has a 144-fold and 10-fold higher affinity for β1i than for the distribution of β1c and β5 subunits. UK-101 induces apoptosis and can be used to study prostate cancer related diseases.
价 格：￥电议型 号：T13247产 地：中国大陆
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T131659Compound 0449-0101；化合物 0449-0101Compound 0449-0101
Compound 0449-0101 is a useful organic compound for research related to life sciences and the catalog number is T131659.
价 格：￥电议型 号：T131659产 地：中国大陆
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T13101TC-MCH 7c；化合物TC-MCH 7cTC-MCH 7c
TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpyridone derivative with MCH1R Ki of 3.4 nM against human. In mice, MCH1R Ki was 3.0 nM.
价 格：￥电议型 号：T13101产 地：中国大陆
