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T10585Bozitinib；化合物BozitinibCBT-101|||PLB-1001；CBT-101|||PLB-1001
Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier permeability. Bozitinib binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.
价 格：￥电议型 号：T10585产 地：中国大陆
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T10426AZ12601011；化合物 T10426AZ12601011
AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
价 格：￥电议型 号：T10426产 地：中国大陆
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T10199GNF-PF-3777；化合物GNF-PF-37778-Nitrotryptanthrin；8-Nitrotryptanthrin
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).
价 格：￥电议型 号：T10199产 地：中国大陆
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T101988-M-PDOT；8-甲氧基-2-丙胺四氢萘8-Methoxy-2-propionamidotetralin|||AH-002；8-Methoxy-2-propionamidotetralin|||A
8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors.8-M-PDOT has anxiolytic activity and may be used to study MT2-induced neuropathic pain.
价 格：￥电议型 号：T10198产 地：中国大陆
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T101978,?9-?Epoxy-?3-?isobutyryloxy-?10-?(2-?methylbutanoyl)?thymol；8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚8-9-epoxy
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.
价 格：￥电议型 号：T10197产 地：中国大陆
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T101967α-Hydroxy-4-cholesten-3-one；化合物 T101967α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in the synthesis of bile acids from cholesterol. It is a PXR agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss and other diseases associated with defective bile acid biosynthesis.It is the physiological substrate for CYP8B1.
价 格：￥电议型 号：T10196产 地：中国大陆
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T101957-O-Geranylscopoletin；化合物 T101957-Geranyloxy-6-methoxycoumarin；7-Geranyloxy-6-methoxycoumarin
7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and stimulant.
价 格：￥电议型 号：T10195产 地：中国大陆
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T101947-Methylguanine；化合物 T101947-Methylguanine
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method.
价 格：￥电议型 号：T10194产 地：中国大陆
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T10191L7-Chlorokynurenic acid；7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA；7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格：￥电议型 号：T10191L产 地：中国大陆
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T101917-Chlorokynurenic acid sodium salt化合物 T101917-CKA sodium salt
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles (Ki: 0.59 μM).
价 格：￥电议型 号：T10191产 地：中国大陆
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T101907-BIA；化合物7-BIA7-BIA
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain.
价 格：￥电议型 号：T10190产 地：中国大陆
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T101897-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene；化合物 T101897-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifen
7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist (IC50: 3.1 μM).
价 格：￥电议型 号：T10189产 地：中国大陆
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T101886RK73；化合物6RK736RK73
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 ?M). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 ?M).
价 格：￥电议型 号：T10188产 地：中国大陆
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T101866-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-化合物 T101866-Quinoxalinecarboxylic-acid,-2,3-bis_b
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, displays antibacterial properties.
价 格：￥电议型 号：T10186产 地：中国大陆
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T101856-Phosphogluconic acid；6-磷酸葡萄糖酸6-Phosphogluconic acid
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.
价 格：￥电议型 号：T10185产 地：中国大陆
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T101846-Methyl-5-azacytidine；化合物 T101846-Methyl-5-azacytidine
6-Methyl-5-azacytidine is a potent DNMT inhibitor.
价 格：￥电议型 号：T10184产 地：中国大陆
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T101836-Methoxytricin；6-甲氧基哌啶6-Methoxytricin
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
价 格：￥电议型 号：T10183产 地：中国大陆
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T101826-Hydroxybenzbromarone；6-羟基苯并溴马隆6-Hydroxybenzbromarone
6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 μM). It is an angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting.
价 格：￥电议型 号：T10182产 地：中国大陆
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T101816-beta-Naloxol D5 hydrochloride；化合物 T101816β-Naloxol D5 hydrochloride；6β-Naloxol D5 hydrochloride
6-beta-Naloxol D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research.
价 格：￥电议型 号：T10181产 地：中国大陆
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T101806-Alpha Naloxol；化合物 T10180Alpha-Naloxol；Alpha-Naloxol
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist and is a human metabolite of naloxone.
价 格：￥电议型 号：T10180产 地：中国大陆
