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T10157Regorafénib N-oxyde (M2)瑞戈非尼杂质 13瑞戈非尼杂质 13
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).
价 格：￥电议型 号：T10157产 地：中国大陆
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T10156CCR3 antagonist 1；CCR3 拮抗剂1CCR3 antagonist 1
CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases.
价 格：￥电议型 号：T10156产 地：中国大陆
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T10154MAO-B-IN-1；化合物 T10154MAO-B-IN-1
MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.
价 格：￥电议型 号：T10154产 地：中国大陆
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T101534-O-Methyl honokiol；4--O-甲基和厚朴酚4-O-Methyl honokiol
4-O-Methyl honokiol, a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist and inhibits NF-κB activity, used for cancer and inflammation research.
价 格：￥电议型 号：T10153产 地：中国大陆
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T10152L4-Methylamino antipyrine hydrochloride；化合物 T10152L4-Methylamino antipyrine hydrochloride
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak anti-inflammatory properties.
价 格：￥电议型 号：T10152L产 地：中国大陆
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T101524-Methylamino antipyrine；4-(甲氨基)安替比林4-Methylamino antipyrine
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak anti-inflammatory properties.
价 格：￥电议型 号：T10152产 地：中国大陆
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T101515-Lipoxygenase-In-1；化合物 T101515-Lipoxygenase-In-1
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
价 格：￥电议型 号：T10151产 地：中国大陆
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T101494-Hydroxypropranolol-d7 hydrochloride；化合物 T10149(±)-4-hydroxy Propranolol D7 hydrochloride|||4-Hydro
4-Hydroxypropranolol D7 hydrochloride is deuterium-labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).
价 格：￥电议型 号：T10149产 地：中国大陆
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T101484-Hydroxynonenal；4-羟基壬烯醛4-HNE；4-羟基壬烯醛|||4-HNE
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
价 格：￥电议型 号：T10148产 地：中国大陆
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T101464-Hydroxyderricin；4-羟基德里辛4-Hydroxyderricin
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-hydroxylase (DBH) activity and possesses antidepressant activity.
价 格：￥电议型 号：T10146产 地：中国大陆
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T101444-Hydroxyatomoxetine D3；化合物 T101444-Hydroxyatomoxetine D3
4-Hydroxyatomoxetine D3 is a deuterium labeled 4-Hydroxyatomoxetine. 4-Hydroxyatomoxetine is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.
价 格：￥电议型 号：T10144产 地：中国大陆
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T10142Lp-Ethynylphenylalanine hydrochloride化合物p-Ethynylphenylalanine hydrochloride4-Ethynyl-L-phenylalanine
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the biosynthesis of serotonin may contribute to the characterization of the role of serotonin in behavioral and physiological activities[1].
价 格：￥电议型 号：T10142L产 地：中国大陆
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T10142p-Ethynylphenylalanine；4-乙炔基苯丙氨酸4-Ethynyl-L-phenylalanine；4-Ethynyl-L-phenylalanine
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.
价 格：￥电议型 号：T10142产 地：中国大陆
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T101404-Diethylaminobenzaldehyde；N,N-二乙基-4-氨基苯甲醛4-Diethylaminobenzaldehyde
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μM).
价 格：￥电议型 号：T10140产 地：中国大陆
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T101394-Desmethyl Istradefylline；化合物 T101394-Desmethyl Istradefylline
4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson´s disease.
价 格：￥电议型 号：T10139产 地：中国大陆
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T101384-Desmethoxy Omeprazole；埃索美拉唑杂质B4-Desmethoxy Omeprazole
4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).
价 格：￥电议型 号：T10138产 地：中国大陆
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T101374-Bromo A23187；化合物 T101374-?Bromo A23187；4-?Bromo A23187
4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.
价 格：￥电议型 号：T10137产 地：中国大陆
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T101364-Acetylsimvastatin；化合物 T101364-Acetylsimvastatin
4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).
价 格：￥电议型 号：T10136产 地：中国大陆
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T101354-Acetamidophenyl acetate；化合物 T101354-Acetamidophenyl acetate
4-Acetamidophenyl acetate is an impurity of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50: 25.8 μM) and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
价 格：￥电议型 号：T10135产 地：中国大陆
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T101344,7,10,13,16-Docosapentaenoic acid；化合物 T101344,7,10,13,16-Docosapentaenoic acid
4,7,10,13,16-Docosapentaenoic acid is an endogenous metabolite.
价 格：￥电议型 号：T10134产 地：中国大陆
