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T83724TPP-1 hydrochloride；化合物 TPP-1 hydrochlorideTargeting PD-L1 Peptide；Targeting PD-L1 Peptide
TPP-1, a peptide inhibitor, targets the interaction between programmed cell death protein 1 (PD-1) and its ligand (PD-L1), binding specifically to PD-L1 with a dissociation constant (Kd) of 94.67 nM. At a concentration of 20 ?M, TPP-1 effectively counteracts the PD-L1-induced suppression of IFN-γ production in anti-CD3-stimulated isolated human CD4+ T cells. Furthermore, TPP-1 demonstrates significant efficacy in reducing tumor volume in a mouse xenograft model of HL-60 leukemia. This model invo
价 格：￥电议型 号：T83724产 地：中国大陆
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T83705BING TFA；化合物 BING TFABlocker of Inter-membrane Stress Responses of Gram-negative Bacteria；Blocker of
BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 ?g/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin
价 格：￥电议型 号：T83705产 地：中国大陆
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T83670F1 TFA；化合物 F1 TFATat-IKIP (46-60)|||Tat-Inhibitor of NF-κB Kinase-interacting Peptide；Tat-IKIP (46-6
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectively blocks LPS-induced phosphorylation of IκB kinase α (IKKα) and IKKβ, along with the nuclear translocation of NF-κB (p65) in mouse peritoneal macrophages at 5 ?M concentration. F1, administered at 5 mg/kg in vivo, significantly reduces IL-6, TNF-α, and IL-1β serum levels and enha
价 格：￥电议型 号：T83670产 地：中国大陆
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T83665α-Helical CRF (9-41) TFA；化合物 α-Helical CRF (9-41) TFAα-Helical Corticotropin-Releasing Factor (9-41)
α-Helical CRF (9-41) is a synthetic peptide antagonist that targets corticotropin-releasing factor (CRF), effectively inhibiting CRF-induced adrenocorticotropic hormone (ACTH) release both in vitro, with isolated rat anterior pituitary cells at concentrations of 0.5 to 5 ?M, and in vivo, in non-anesthetized, intact rats at doses ranging from 0.02 to 0.6 ?mol/kg. Moreover, it prevents stress-induced ACTH release at a dose of 0.6 ?mol/kg in rats and demonstrates the ability to enhance social inter
价 格：￥电议型 号：T83665产 地：中国大陆
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T83663Mn(III) Protoporphyrin IX Chloride；化合物 Mn(III) Protoporphyrin IX ChlorideManganese(III) Protoporphyr
Mn(III) protoporphyrin IX chloride is a metalloporphyrin that, at a concentration of 10 ?M, promotes mRNA expression of δ-aminolevulinate synthase and heme oxygenase (HO) in chick embryo liver cells, enzymes crucial for the initial steps in heme biosynthesis and breakdown, respectively. Additionally, this compound has been incorporated into nanobialys for magnetic resonance imaging (MRI) of fibrin clots in vitro and utilized in the creation of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histi
价 格：￥电议型 号：T83663产 地：中国大陆
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T83601(+)-Diasyringaresinol；化合物 (+)-Diasyringaresinol(+)-Diasyringaresinol
(+)-Diasyringaresinol, a lignan derived from Aquilaria agallocha seeds [1], exhibits potential pharmacological properties.
价 格：￥电议型 号：T83601产 地：中国大陆
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T83545(E)-(-)-Aspongopusamide B；化合物 (E)-(-)-Aspongopusamide B(E)-(-)-Aspongopusamide B
(E)-(-)-Aspongopusamide B (Compound 9), a natural product, is isolated from the insect Aspongopus chinensis [1].
价 格：￥电议型 号：T83545产 地：中国大陆
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T83527(Rac)-Neurodegenerative Disorder-Targeting Compound 1；化合物 (Rac)-Neurodegenerative Disorder-Targeting
(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
价 格：￥电议型 号：T83527产 地：中国大陆
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T83516(Z)-2-Angeloyloxymethyl-2-butenoic；化合物 (Z)-2-Angeloyloxymethyl-2-butenoic(Z)-2-Angeloyloxymethyl-2-b
(Z)-2-Angeloyloxymethyl-2-butenoic acid is a naturally occurring compound isolated from the roots of Anthriscus sylvestris Hoffm. [1].
价 格：￥电议型 号：T83516产 地：中国大陆
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T83509[Arg6]-β-Amyloid (1-40), england mutation；化合物 [Arg6]-β-Amyloid (1-40), england mutation[Arg6]-β-Amyl
β-Amyloid (1-40), England mutation, is a biologically active peptide with a histidine (His) to arginine (Arg) substitution at position 6, known to enhance oligomerization kinetics that serve as fibril seeds and increase neurotoxicity in cultured neurons. This alteration is one of several mutations in the beta-amyloid precursor gene implicated in autosomal dominant Alzheimer´s Disease across multiple kindreds.
价 格：￥电议型 号：T83509产 地：中国大陆
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T83508[Arg6]-β-Amyloid (1-42), england mutation；化合物 [Arg6]-β-Amyloid (1-42), england mutation[Arg6]-β-Amyl
[Arg6]-β-Amyloid (1-42), England mutation, is a biologically active peptide associated with autosomal dominant Alzheimer´s Disease in various kindreds. The English (H6R) mutation disrupts H6 interactions due to several mutations in the beta-amyloid precursor gene.
价 格：￥电议型 号：T83508产 地：中国大陆
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T83484[Tyr0] Corticotropin Releasing Factor, ovine；化合物 [Tyr0] Corticotropin Releasing Factor, ovine[Tyr0]
[Tyr^0] Corticotropin Releasing Factor, ovine, is a hypothalamic hormone sourced from sheep that prompts the secretion of adrenocorticotropic hormone (ACTH) and β-endorphin [1] [2].
价 格：￥电议型 号：T83484产 地：中国大陆
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T83483[Val4] Angiotensin III；化合物 [Val4] Angiotensin III[Val4] Angiotensin III
[Val4] Angiotensin III is an angiotensin III peptide variant and a potent full agonist for Gαq and βarr2 signaling pathways, exhibiting pEC50 values of 8.31 and 8.44, respectively [1].
价 格：￥电议型 号：T83483产 地：中国大陆
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T8346211-O-Syringylbergenin；化合物 11-O-Syringylbergenin11-O-Syringylbergenin
11-O-Syringylbergenin, a bergenin derivative, has been isolated from the entire plant of Corylopsis willmottiae Rehd. et Wils [1].
价 格：￥电议型 号：T83462产 地：中国大陆
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T8343917α-Deacetyltanghinin；化合物 17α-Deacetyltanghinin17α-Deacetyltanghinin
17α-Deacetyltanghinin is a monoxide isolated from the air-dried leaves of Cerbera odollam [1].
价 格：￥电议型 号：T83439产 地：中国大陆
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T8343817β-Tanghinigenin；化合物 17β-Tanghinigenin17β-Tanghinigenin
17β-Tanghinigenin is a glucos-3-ulosyl-thevetoside [1].
价 格：￥电议型 号：T83438产 地：中国大陆
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T8339823-Acetylshengmanol 3-O-β-D-xylopyranoside；化合物 23-Acetylshengmanol 3-O-β-D-xylopyranosideAcetylsheng
23-Acetylshengmanol 3-O-β-D-xylopyranoside (Acetylshengmanol xyloside), a 9,19-cyclolanostane type triterpenoid, is isolated from the roots of Actaea pachypoda [1].
价 格：￥电议型 号：T83398产 地：中国大陆
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T833653′-O-Angeloylhamaudol；化合物 3′-O-Angeloylhamaudol3′-O-Angeloylhamaudol
3′-O-Angeloylhamaudol, a coumarin derivative, is isolated from Radix Saposhnikoviae [1].
价 格：￥电议型 号：T83365产 地：中国大陆
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T833005′-Des-O-methylharringtonine；化合物 5′-Des-O-methylharringtonine5′-Des-O-methylharringtonine
5′-Des-O-methylharringtonine, a natural product, can be isolated from Cephalotaxus harringtonia [1].
价 格：￥电议型 号：T83300产 地：中国大陆
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T8328STING agonist-1；化合物STING agonist-1G10；G10
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
价 格：￥电议型 号：T8328产 地：中国大陆
