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T11137(E)-GABAB receptor antagonist 1;(E)-GABAB受体拮抗剂-1(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11137产 地:中国大陆
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T11077Dopamine D2 receptor antagonist-1;多巴胺D2受体拮抗剂-1Dopamine D2 receptor antagonist-1
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
价 格:¥电议型 号:T11077产 地:中国大陆
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T10911H3 receptor antagonist 1;化合物 T10911H3 receptor antagonist 1
H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.
价 格:¥电议型 号:T10911产 地:中国大陆
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T10889CRTh2 antagonist 2;CRTh2拮抗剂2CRTh2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
价 格:¥电议型 号:T10889产 地:中国大陆
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T10820L1Ciraparantag acetate;化合物Ciraparantag acetateCiraparantag acetate(1438492-26-2 Free base);Ciraparanta
Ciraparantag acetate, an anticoagulant reversal agent, is a small molecule specifically designed to bind noncovalently by charge-charge interaction to unfractionated heparin and low-molecular-weight heparin.?It shows binding characteristics that are similar to those of direct oral anticoagulants (DOACs).
价 格:¥电议型 号:T10820L1产 地:中国大陆
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T10820LCiraparantag TFA;化合物 T10820LPER977 TFA;PER977 TFA
Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820L产 地:中国大陆
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T10820Ciraparantag化合物 T10820PER977
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820产 地:中国大陆
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T10714CCR5 antagonist 1;化合物 T10714CCR5 antagonist 1
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
价 格:¥电议型 号:T10714产 地:中国大陆
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T10713CCR4 antagonist 2;化合物 T10713CCR4 antagonist 2
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
价 格:¥电议型 号:T10713产 地:中国大陆
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T10712CCR2 antagonist 3;化合物CCR2 antagonist 3AZD-2927|||AZD2927;AZD-2927|||AZD2927
CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.
价 格:¥电议型 号:T10712产 地:中国大陆
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T10711CCR2 antagonist 1;化合物 T10711CCR2 antagonist 1
CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).
价 格:¥电议型 号:T10711产 地:中国大陆
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T10710CCR1 antagonist 9;化合物 T10710CCR1 antagonist 9
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
价 格:¥电议型 号:T10710产 地:中国大陆
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T10709CCR1 antagonist 7;化合物 T10709CCR1 antagonist 7
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
价 格:¥电议型 号:T10709产 地:中国大陆
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T10708CCR1 antagonist 6;CCR1拮抗剂6CCR1 antagonist 6
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
价 格:¥电议型 号:T10708产 地:中国大陆
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T10707CCK-B Receptor Antagonist 2;化合物 T10707CCK-B Receptor Antagonist 2
CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).
价 格:¥电议型 号:T10707产 地:中国大陆
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T10665Calcium-Sensing Receptor Antagonists I;化合物 T10665Calcium-Sensing Receptor Antagonists I
Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.
价 格:¥电议型 号:T10665产 地:中国大陆
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T10560P2X3 antagonist 34;化合物 T10560BLU-5937;BLU-5937
P2X3 antagonist 34, a potent, selective, and orally active antagonist, targets the P2X3 homotrimeric receptor, exhibiting IC50s of 25 nM, 92 nM, and 126 nM for human, rat, and guinea pig P2X3 receptors respectively. It shows reduced activity against P2X2/3 heterotrimeric receptors across human, rat, and guinea pig models. Notably, this compound demonstrates a significant anti-tussive effect without altering taste[1].
价 格:¥电议型 号:T10560产 地:中国大陆
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T10510CB1 antagonist 1;化合物 T10510CB1 antagonist 1
CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and gastrointestinal disorders, psychosis, and cardiovascular.
价 格:¥电议型 号:T10510产 地:中国大陆
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T104985-HT2A antagonist 1;化合物 T104985-HT2A antagonist 1
5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.
价 格:¥电议型 号:T10498产 地:中国大陆
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T10359AR antagonist 1;化合物AR antagonist 1AR antagonist 1
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.
价 格:¥电议型 号:T10359产 地:中国大陆