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T11351Galanthamine N-Oxide;加兰他明 N-氧化物Galanthamine N-Oxide
Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate accommodation within the active sites of Torpedo californica AChE (TcAChE), human AChE (hAChE), and human BChE (hBChE) enzymes.
价 格:¥电议型 号:T11351产 地:中国大陆
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T11350GABAB receptor antagonist 1;化合物 T11350GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11350产 地:中国大陆
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T1135Vitamin D3;维生素D3Cholecalciferol|||Colecalciferol;维生素D3|||Cholecalciferol|||Colecalciferol
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
价 格:¥电议型 号:T1135产 地:中国大陆
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T11348G907;化合物G907G907
G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli MsbA with an IC50 value of 18 nM.
价 格:¥电议型 号:T11348产 地:中国大陆
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T11347G6PD activator AG1;化合物 T11347G6PD activator AG1
G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 μΜ.
价 格:¥电议型 号:T11347产 地:中国大陆
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T11346LG3-C12 acetate(848301-94-0 free base);化合物G3-C12 acetateG3-C12 acetate(848301-94-0 free base)
G3-C12 acetate shows anticancer activity.?is a galectin-3 binding peptide, with Kd of 88 nM.
价 格:¥电议型 号:T11346L产 地:中国大陆
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T11346G3-C12;化合物 T11346G3-C12
G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
价 格:¥电议型 号:T11346产 地:中国大陆
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T11345LLerociclib dihydrochloride;化合物Lerociclib dihydrochlorideG1T38 dihydrochloride;G1T38 dihydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
价 格:¥电议型 号:T11345L产 地:中国大陆
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T11345Lerociclib;化合物 T11345G1T38;G1T38
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 2nM, 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
价 格:¥电议型 号:T11345产 地:中国大陆
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T11344G150;化合物G150G150
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
价 格:¥电议型 号:T11344产 地:中国大陆
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T11343G0507;化合物 T11343G0507
G0507 is a pyrrolopyrimidinedione compound that serves as a potent inhibitor of Escherichia coli growth, effectively inducing the extracytoplasmic σE stress response. It acts as a valuable chemical probe, specifically designed to dissect lipoprotein trafficking in Gram-negative bacteria. Notably, G0507 demonstrates strong inhibitory activity against the LolCDE ABC Transporter.
价 格:¥电议型 号:T11343产 地:中国大陆
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T11342LG-5555;化合物G-5555G-5555
G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).
价 格:¥电议型 号:T11342L产 地:中国大陆
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T11342G-5555 hydrochloride (1648863-90-4 free base);化合物 T11342G-5555 hydrochloride;G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
价 格:¥电议型 号:T11342产 地:中国大陆
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T11341FXIa-IN-1;化合物 T11341FXIa-IN-1
FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.
价 格:¥电议型 号:T11341产 地:中国大陆
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T11340Furprofen;化合物 FurprofenFurprofen
Furprofen is a non-steroidal anti-inflammatory agent that inhibits prostate (PGE) synthesis and is used in the study of rheumatoid arthritis and osteoarthritis.
价 格:¥电议型 号:T11340产 地:中国大陆
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T1134Clofoctol氯福克酚叔辛酚氯|||氯福克酚
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections.
价 格:¥电议型 号:T1134产 地:中国大陆
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T11339LFuregrelate;呋格雷酸Furegrelate
FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.
价 格:¥电议型 号:T11339L产 地:中国大陆
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T11339Furegrelate sodium;化合物Furegrelate sodiumU-63557A;U-63557A
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.
价 格:¥电议型 号:T11339产 地:中国大陆
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T11338Furamidine;化合物 T11338DB75|||NSC 305831;DB75|||NSC 305831
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and
价 格:¥电议型 号:T11338产 地:中国大陆
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T11337Fumarate hydratase-IN-1;Fumarate hydratase 抑制剂1Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
价 格:¥电议型 号:T11337产 地:中国大陆