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T17997HO-PEG-amine (MW 1000);化合物 T17997HO-PEG-amine (MW 1000)
HO-PEG-amine (MW 1000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17997产 地:中国大陆
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T1776LPlerixafor octahydrochloride;盐酸普乐沙福JM3100 octahydrochloride|||Plerixafor 8HCl (AMD3100 8HCl)|||Pleri
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity.
价 格:¥电议型 号:T1776L产 地:中国大陆
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T1776Plerixafor;普乐沙福JM3100|||AMD 3100|||AMD-3329;普乐沙福|||JM3100|||AMD 3100|||AMD-3329
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
价 格:¥电议型 号:T1776产 地:中国大陆
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T17553Biotin-PEG-triethoxysilane (MW 1000);化合物 T17553Biotin-PEG-triethoxysilane (MW 1000)
Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17553产 地:中国大陆
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T17552Biotin-PEG-Biotin (MW 1000);化合物 T17552Biotin-PEG-Biotin (MW 1000)
Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker employed in PROTAC synthesis[1].
价 格:¥电议型 号:T17552产 地:中国大陆
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T17460Azide-PEG-azide (MW 10000);化合物 T17460Azide-PEG-azide (MW 10000)
Azide-PEG-azide (MW 10000) is a polyethylene glycol (PEG)-based linker for PROTACs synthesis. It serves as an essential component in assembling PROTAC molecules[1].
价 格:¥电议型 号:T17460产 地:中国大陆
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T17360Acrylate-PEG-OH (MW 10000);化合物 T17360Acrylate-PEG-OH (MW 10000)
Acrylate-PEG-OH (MW 10000) is a Polyethylene Glycol (PEG) derived PROTAC linker utilized for synthesizing PROTACs[1].
价 格:¥电议型 号:T17360产 地:中国大陆
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T17358Acrylate-PEG-NH2 (MW 10000);化合物 T17358Acrylate-PEG-NH2 (MW 10000)
Acrylate-PEG-NH2 (MW 10000) is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17358产 地:中国大陆
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T17238VU0152100;化合物VU0152100VU152100;VU152100
VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).
价 格:¥电议型 号:T17238产 地:中国大陆
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T17100Tin(IV) mesoporphyrin IX dichloride;化合物 T17100Stannsoporfin;Stannsoporfin
Tin(IV) mesoporphyrin IX dichloride is a heme oxygenase inhibitor being developed for the prevention of hyperbilirubinemia in infants at risk of developing jaundice.
价 格:¥电议型 号:T17100产 地:中国大陆
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T16962SW-100;化合物SW-100SW-100
SW-100 is a selective histone deacetylase 6 inhibitor (IC50: 2.3 nM). It also shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays an obviously improved ability to cross the blood-brain-barrier.
价 格:¥电议型 号:T16962产 地:中国大陆
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T16829(S)-BI-1001;化合物 T16829(S)-BI-1001
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
价 格:¥电议型 号:T16829产 地:中国大陆
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T16784Roniciclib;化合物RoniciclibBAY 1000394;BAY 1000394
Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.
价 格:¥电议型 号:T16784产 地:中国大陆
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T16765RNPA1000;化合物 T16765RNPA1000
RNPA1000 is an attractive antimicrobial development candidate and RnpA inhibitor.
价 格:¥电议型 号:T16765产 地:中国大陆
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T16391ON-013100;化合物ON-013100ON-013100
ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.
价 格:¥电议型 号:T16391产 地:中国大陆
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T16100Balamapimod;化合物 T16100MKI 833;MKI 833
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
价 格:¥电议型 号:T16100产 地:中国大陆
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T16022Arhalofenate;芳卤芬酯JNJ 39659100|||MBX 102;JNJ 39659100|||芳卤芬酯|||4-氯-ALPHA-[3-(三氟甲基)苯氧基]苯乙酸 2-(乙酰基氨基)乙酯
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T16022产 地:中国大陆
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T15801LY210073;化合物 T15801LY210073
LY210073 is an antagonist of the Leukotriene B4 (LTB4) receptor (IC50: 6.2 nM).
价 格:¥电议型 号:T15801产 地:中国大陆
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T15748LG100754;化合物LG100754UVI 2112;UVI 2112
LG100754 (UVI 2112) is an insulin sensitizer that functions through RXR. LG100754 is an RXR dimer modulator. LG100754 acts as an RXR: RXR homodimer antagonist, but functions as an agonist towards RXR: PPARα and RXR: PPARγ heterodimers.
价 格:¥电议型 号:T15748产 地:中国大陆
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T15480HG6-64-1;化合物 T15480HMSL 10017-101-1;HMSL 10017-101-1
HG6-64-1 is a potent and selective inhibitor of B-Raf (IC50: 0.09 μM on B-raf V600E transformed Ba/F3 cells).
价 格:¥电议型 号:T15480产 地:中国大陆