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T6172MRS 2578;化合物MRS 2578MRS 2578
MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
价 格:¥电议型 号:T6172产 地:中国大陆
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T61704RSV-IN-6;化合物 RSV-IN-6RSV-IN-6
RSV-IN-6 (Compound 53) is a specific agent that effectively inhibits the respiratory syncytial virus (RSV) by targeting the M2-1 protein. It shows strong potency, with EC50 values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strains, respectively [1].
价 格:¥电议型 号:T61704产 地:中国大陆
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T61689ThrRS-IN-1;化合物 ThrRS-IN-1ThrRS-IN-1
ThrRS-IN-1 (Compound 30d) is a potent inhibitor of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica (Se ThrRS), exhibiting an IC50 of 1.4 μM and a Kd of 1.36 μM. It uniquely targets both the tRNA Thr and L-threonine binding sites of ThrRS, demonstrating significant antibacterial activities [1].
价 格:¥电议型 号:T61689产 地:中国大陆
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T61613SARS-CoV-2-IN-17;化合物 SARS-CoV-2-IN-17SARS-CoV-2-IN-17
SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to NPro with a low Kd value of 7.82 μM, highlighting its potency as a NPro ligand [1].
价 格:¥电议型 号:T61613产 地:中国大陆
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T61591SARS-CoV-2-IN-20;化合物 SARS-CoV-2-IN-20SARS-CoV-2-IN-20
SARS-CoV-2-IN-20 (Compound 1a) is a highly effective inhibitor of SARS-CoV-2, displaying an impressive EC50 value of 6.5 μM. With its exceptional inhibitory properties, SARS-CoV-2-IN-20 holds great potential for advancing research on infectious diseases [1].
价 格:¥电议型 号:T61591产 地:中国大陆
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T6146Dorsomorphin dihydrochloride;化合物Dorsomorphin dihydrochlorideBML-275 2HCl|||Compound C dihydrochlorid
Dorsomorphin dihydrochloride (BML-275 2HCl) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin dihydrochloride inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy, and possesses antitumor activity.
价 格:¥电议型 号:T6146产 地:中国大陆
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T61343RSV/IAV-IN-1;化合物 RSV/IAV-IN-1RSV/IAV-IN-1
RSV/IAV-IN-1 (compound 14e) is a potent dual inhibitor of RSV/IAV with lower cytotoxicity compared to Ribavirin, suggesting promising potential for researching RSV and/or IAV infections [1].
价 格:¥电议型 号:T61343产 地:中国大陆
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T61291RSV/IAV-IN-2;化合物 RSV/IAV-IN-2RSV/IAV-IN-2
RSV/IAV-IN-2 (compound 14c) represents a powerful dual inhibitor of RSV/IAV, exhibiting lower cytotoxicity compared to the clinical drug Ribavirin. It holds promise for the research of RSV and/or IAV infections [1].
价 格:¥电议型 号:T61291产 地:中国大陆
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T61217RSV-IN-3;化合物 RSV-IN-3RSV-IN-3
RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1].
价 格:¥电议型 号:T61217产 地:中国大陆
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T6114Nifursol硝呋索尔硝呋索尔|||尼呋索尔
Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
价 格:¥电议型 号:T6114产 地:中国大陆
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T61028Mitiperstat;化合物MitiperstatAZD4831;AZD4831
Mitiperstat is a potent myeloperoxidase (MPO) inhibitor that is effective in preventing cardiovascular diseases such as heart failure and coronary artery disease.
价 格:¥电议型 号:T61028产 地:中国大陆
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T60974MetRS-IN-1;化合物 MetRS-IN-1MetRS-IN-1
MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].
价 格:¥电议型 号:T60974产 地:中国大陆
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T60962SARS-CoV-2-IN-18;化合物 SARS-CoV-2-IN-18SARS-CoV-2-IN-18
SARS-CoV-2-IN-18 (Compound 26) is a potent inhibitor of SARS-CoV-2 3C-like protease (IC50 = 45 nM) [1].
价 格:¥电议型 号:T60962产 地:中国大陆
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T60922RSK-IN-1;化合物 RSK-IN-1RSK-IN-1
RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].
价 格:¥电议型 号:T60922产 地:中国大陆
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T60919SARS-CoV-2-IN-13;化合物SARS-CoV-2-IN-13SARS-CoV-2-IN-13
SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when administered orally. SARS-CoV-2-IN-13 is a potent SARS-CoV-2 inhibitor with an IC 50 of 0.057 μM [1].
价 格:¥电议型 号:T60919产 地:中国大陆
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T60910RSV-IN-4;化合物 RSV-IN-4RSV-IN-4
RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1].
价 格:¥电议型 号:T60910产 地:中国大陆
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T60861SARS-CoV-2 nsp3-IN-1;化合物 SARS-CoV-2 nsp3-IN-1SARS-CoV-2 nsp3-IN-1
SARS-CoV-2 nsp3-IN-1 (Compound 15c) shows significant selectivity for coronavirus macrodomains, especially SARS-CoV-2 Mac1. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity that is an inhibitor of Mac1 (IC50 = 6.1 μM) [1].
价 格:¥电议型 号:T60861产 地:中国大陆
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T60841SARS-CoV-2-IN-23;化合物 SARS-CoV-2-IN-23SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].
价 格:¥电议型 号:T60841产 地:中国大陆
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T60818SARS-CoV-2-IN-15;化合物 SARS-CoV-2-IN-15SARS-CoV-2-IN-15
SARS-CoV-2-IN-15 (compound 11) is a niclosamide analogue that contains higher stability in human plasma and liver S9 enzymes assay than niclosamide. It improves bioavailability and half-life when administered orally. SARS-CoV-2-IN-15 is a potent SARS-CoV-2 inhibitor with an IC 50 of 0.49 μM [1].
价 格:¥电议型 号:T60818产 地:中国大陆
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T60785SARS-CoV-2-IN-6;化合物 SARS-CoV-2-IN-6SARS-CoV-2-IN-6
SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.
价 格:¥电议型 号:T60785产 地:中国大陆