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  • T39480Lexanersen；LexanersenWVE-120102|||Lexanersen；WVE-120102|||Lexanersen

    Lexanersen (WVE-120102), an antisense oligonucleotide, is utilized in Huntington´s disease research.

    价 格：￥电议型 号：T39480产 地：中国大陆

  • T39479Rovanersen；RovanersenWVE-120101|||Rovanersen；WVE-120101|||Rovanersen

    Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.

    价 格：￥电议型 号：T39479产 地：中国大陆

  • T39455Viltolarsen；ViltolarsenNS-065|||NCNP-01；NS-065|||NCNP-01

    Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets the splicing of exon 53 in the dystrophin gene. It is utilized in research related to Duchenne muscular dystrophy (DMD).

    价 格：￥电议型 号：T39455产 地：中国大陆

  • T39304Vutrisiran；VutrisiranALN-TTRsc02；ALN-TTRsc02

    Vutrisiran (ALN-TTRsc02) is an investigational, liver-directed small interfering ribonucleic acid (siRNA) compound designed for research on transthyretin (TTR)-mediated amyloidosis.

    价 格：￥电议型 号：T39304产 地：中国大陆

  • T39295RemlarsenRemlarsenMRG-201

    Remlarsen (MRG-201), a miR-29b mimic, functions as a miR-29b agonist with the potential to prevent the formation of fibrotic scars or cutaneous fibrosis.

    价 格：￥电议型 号：T39295产 地：中国大陆

  • T39294CobomarsenCobomarsenMRG-106|||Cobomarsen

    Cobomarsen (MRG-106) is an oligonucleotide inhibitor targeting miR-155. This compound effectively suppresses various gene pathways involved in cell survival, such as JAK/STAT, MAPK/ERK, and PI3K/AKT. Cobomarsen is particularly valuable in the study of B-cell lymphoma.

    价 格：￥电议型 号：T39294产 地：中国大陆

  • T3925Astragaloside I；黄芪皂苷ICyclosieversioside B|||Astrasieversianin IV；黄芪皂苷I|||Cyclosieversioside B|||Astr

    Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus. It can stimulate osteoblast differentiation through the Wnt/β-catenin signaling pathway and can be used to study osteogenic activity.

    价 格：￥电议型 号：T3925产 地：中国大陆

  • T3924Astragaloside II；黄芪皂苷 IIAstrasieversianin VIII；黄芪皂苷 II|||Astrasieversianin VIII

    Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, proliferation, and mineralization, through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.

    价 格：￥电议型 号：T3924产 地：中国大陆

  • T39166Tominersen；TominersenIONIS-HTTRx|||RG6042；IONIS-HTTRx|||RG6042

    Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen can be used for the research of Huntington’s disease.

    价 格：￥电议型 号：T39166产 地：中国大陆

  • T39108Irsenontrine maleateIrsenontrine maleateE2027 maleate

    Irsenontrine (E2027) maleate is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9). It can be utilized in the study of neurological diseases.

    价 格：￥电议型 号：T39108产 地：中国大陆

  • T39068Fomivirsen sodium；Fomivirsen sodiumFomivirsen sodium

    Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation.

    价 格：￥电议型 号：T39068产 地：中国大陆

  • T3893Forsythoside B连翘酯苷 B连翘酯苷 B|||连翘脂苷B

    Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effects with a favorable therapeutic time-window, reduce of cerebral ischemia and reperfusion injury degree, attenuating blood-brain barrier (BBB) breakdown; Rescued cardiac function from I/R injury. Forsythoside B has antisepsis effect, is mediated by decreasing local and systemic lev

    价 格：￥电议型 号：T3893产 地：中国大陆

  • T38918Revusiran；RevusiranALN-TTRSC；ALN-TTRSC

    Revusiran (ALN-TTRSC) is a first-generation short interfering RNA (siRNA) that specifically targets transthyretin (TTR) mRNA. It is utilized in TTR-mediated amyloidosis research.

    价 格：￥电议型 号：T38918产 地：中国大陆

  • T38909Inotersen sodium；Inotersen sodiumISIS-420915 sodium；ISIS-420915 sodium

    Inotersen sodium, also known as ISIS-420915 sodium, is a 2′-O-methoxyethyl-modified antisense oligonucleotide compound. It effectively inhibits transthyretin (TTR) protein production by targeting the TTR RNA transcript, thereby reducing TTR transcript levels. Inotersen sodium holds potential for research on hereditary TTR amyloidosis polyneuropathy.

    价 格：￥电议型 号：T38909产 地：中国大陆

  • T38860Golodirsen；GolodirsenGolodirsen|||SRP-4053；Golodirsen|||SRP-4053

    Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind and target exon 53 of dystrophin pre-mRNA, with applications in the investigation of Duchenne muscular dystrophy (DMD).

    价 格：￥电议型 号：T38860产 地：中国大陆

  • T38859Casimersen；CasimersenSRP-4045；SRP-4045

    Casimersen (SRP-4045) is an antisense oligonucleotide, specifically belonging to the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, effectively restoring the open-reading frame by skipping exon 45. This action ultimately leads to the production of a functional dystrophin protein, albeit internally truncated. Casimersen finds utility in Duchenne muscular dystrophy (DMD) research.

    价 格：￥电议型 号：T38859产 地：中国大陆

  • T38829Lademirsen；LademirsenRG-012|||SAR339375；RG-012|||SAR339375

    Lademirsen (SAR339375; RG-012) is a highly specific antisense oligonucleotide (ASO) targeting miR-21 . Lademirsen has the potential for Alport nephropathy research.

    价 格：￥电议型 号：T38829产 地：中国大陆

  • T38775LeuRS-IN-1；LeuRS-IN-1LeuRS-IN-1

    LeuRS-IN-1 is a highly potent and orally active inhibitor of the leucyl-tRNA synthetase enzyme derived from Mycobacterium tuberculosis (M.tb LeuRS). It exhibits significant inhibitory activity against M.tb LeuRS with IC 50 and Kd values of 0.06 μM and 0.075 μM, respectively. Additionally, LeuRS-IN-1 effectively inhibits human cytoplasmic LeuRS with an IC 50 value of 38.8 μM and suppresses protein synthesis in HepG2 cells with an EC 50 value of 19.6 μM.

    价 格：￥电议型 号：T38775产 地：中国大陆

  • T38773LeuRS-IN-1 hydrochloride；LeuRS-IN-1 hydrochlorideLeuRS-IN-1 hydrochloride

    LeuRS-IN-1 hydrochloride is a potent and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS). It has IC 50 and Kd values of 0.06 μM and 0.075 μM, respectively, for M.tb LeuRS. Additionally, LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS with an IC 50 of 38.8 μM and HepG2 protein synthesis with an EC 50 of 19.6 μM.

    价 格：￥电议型 号：T38773产 地：中国大陆

  • T38729Melarsonyl dipotassium；美拉胂钾Melarsonic acid dipotassium；美拉胂钾|||Melarsonic acid dipotassium

    Melarsonyl dipotassium, also known as melarsonic acid dipotassium, is a potent anthelmintic agent with the ability to effectively inhibit parasites.

    价 格：￥电议型 号：T38729产 地：中国大陆

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