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  • T37127L-AP4 monohydrate；L-AP4 monohydrateL-AP4 monohydrate；L-AP4 monohydrate

    L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively[1][2].

    价 格：￥电议型 号：T37127产 地：中国大陆

  • T369735-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)；5-Phospho-D-ribose 1-diphosphate (sodium salt

    5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase.

    价 格：￥电议型 号：T36973产 地：中国大陆

  • T36917Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)；Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)Ethynyl E

    Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2

    价 格：￥电议型 号：T36917产 地：中国大陆

  • T36916Estrone-3-Glucuronide (sodium salt hydrate)；Estrone-3-Glucuronide (sodium salt hydrate)Estrone-3-Glu

    Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women.

    价 格：￥电议型 号：T36916产 地：中国大陆

  • T36911Pramlintide (acetate hydrate)；Pramlintide (acetate hydrate)Pramlintide (acetate hydrate)

    Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively). Pramlintide inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner.

    价 格：￥电议型 号：T36911产 地：中国大陆

  • T36827Acetoacetyl Coenzyme A (sodium salt hydrate)；Acetoacetyl Coenzyme A (sodium salt hydrate)Acetoacetyl

    Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis.[3],[4] Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.[5]

    价 格：￥电议型 号：T36827产 地：中国大陆

  • T36807Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)；Estradiol 17-(β-D-Glucuronide) (sodium salt hyd

    Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2

    价 格：￥电议型 号：T36807产 地：中国大陆

  • T36779NG 25 (hydrochloride hydrate)；NG 25 (hydrochloride hydrate)NG 25 (hydrochloride hydrate)

    NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38α (IC50s = 56.4, 82.3, and 102 nM, respectively). NG 25 (100 nM) prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectiv

    价 格：￥电议型 号：T36779产 地：中国大陆

  • T36740Guanosine 5’-diphosphate (sodium salt hydrate)；Guanosine 5’-diphosphate (sodium salt hydrate)Guanosi

    Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.3

    价 格：￥电议型 号：T36740产 地：中国大陆

  • T36639Donecopride (fumarate hydrate)；Donecopride (fumarate hydrate)Donecopride (fumarate hydrate)

    Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= 3,530 nM) but does bind to 5-HT2Band sigma-2 (σ2) receptors (Ki= 1.6 nM for both) in a panel of 42 neurotransmitter receptors and transporters. Donecopride induces release of soluble amyloid precursor protein-α (sAPP-α) in COS-7 cells transiently expressing 5-HT4with an EC50value

    价 格：￥电议型 号：T36639产 地：中国大陆

  • T36600Cefsulodin (sodium salt hydrate)；Cefsulodin (sodium salt hydrate)Cefsulodin (sodium salt hydrate)

    Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2

    价 格：￥电议型 号：T36600产 地：中国大陆

  • T36503Sodium Hydrogen Sulfide (hydrate)；硫氢化钠水合物Sodium Hydrogen Sulfide (hydrate)

    Sodium Hydrogen Sulfide (hydrate) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has been used to suggest that H2S promotes neutrophil migration, reduces airway inflammation, and protects neurites, heart, and intestine from chemical or ischemic-repe

    价 格：￥电议型 号：T36503产 地：中国大陆

  • T36300Uridine-5’-monophosphate (sodium salt hydrate)；Uridine-5’-monophosphate (sodium salt hydrate)Uridine

    Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements.

    价 格：￥电议型 号：T36300产 地：中国大陆

  • T36296BIO5192 hydrate；BIO5192 hydrateBIO5192 hydrate

    BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2].

    价 格：￥电议型 号：T36296产 地：中国大陆

  • T36268VH 032 Linker 3 (hydrate)；VH 032 Linker 3 (hydrate)VH 032 Linker 3 (hydrate)

    VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1.

    价 格：￥电议型 号：T36268产 地：中国大陆

  • T36224N-Hippuryl-His-Leu (hydrate)；N-Hippuryl-His-Leu (hydrate)N-Hippuryl-His-Leu (hydrate)

    N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors.,

    价 格：￥电议型 号：T36224产 地：中国大陆

  • T361223-O-methyl-L-DOPA (hydrate)；3-O-methyl-L-DOPA (hydrate)3-O-methyl-L-DOPA (hydrate)

    3-O-methyl-L-DOPA is a metabolite of L-DOPA , produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.

    价 格：￥电议型 号：T36122产 地：中国大陆

  • T36081Trehalose 6-phosphate (potassium salt hydrate)；Trehalose 6-phosphate (potassium salt hydrate)Trehalo

    Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).5In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucro

    价 格：￥电议型 号：T36081产 地：中国大陆

  • T36066NADP+ (sodium salt hydrate)；NADP+ (sodium salt hydrate)NADP+ (sodium salt hydrate)

    NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth

    价 格：￥电议型 号：T36066产 地：中国大陆

  • T36024FR179642 (hydrate)；FR179642 (hydrate)FR179642 (hydrate)；FR179642 (hydrate)

    FR179642 is the cyclic peptide nucleus of the lipopeptide antifungal FR901379 and an intermediate in the synthesis of the echinocandin antifungal FK463 .1,2

    价 格：￥电议型 号：T36024产 地：中国大陆

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