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T35964MitoTEMPO hydrate;MitoTEMPO (hydrate)MitoTEMPO hydrate
MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. Mitochondrial targeting of superoxide scavenging via mitoTEMPO has been examined for potential therapeutic benefit to a variety of mitochondrial dysfunctions arising from
价 格:¥电议型 号:T35964产 地:中国大陆
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T357204’-hydroxy Atomoxetine Glucuronide (hydrate);4’-hydroxy Atomoxetine Glucuronide (hydrate)4’-hydroxy
4’-hydroxy Atomoxetine glucuronide is a metabolite of the norepinephrine transporter (NET) inhibitor atomoxetine .1It is formed from atomoxetine by glucuronidation of the intermediate metabolite 4-hydroxy atomoxetine.2
价 格:¥电议型 号:T35720产 地:中国大陆
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T35718N-desmethyl Rosuvastatin (sodium salt hydrate);N-desmethyl Rosuvastatin (sodium salt hydrate)N-desme
N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP2C19 and CYP3A4.1
价 格:¥电议型 号:T35718产 地:中国大陆
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T35691Myristoyl Coenzyme A (hydrate);Myristoyl Coenzyme A (hydrate)Myristoyl Coenzyme A (hydrate)
Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells. It is also a substrate in the de novo synthesis of phosphatidylinositol .
价 格:¥电议型 号:T35691产 地:中国大陆
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T35630bpV(pic) (potassium hydrate);bpV(pic) (potassium hydrate)bpV(pic) (potassium hydrate)
bpV(pic) (potassium hydrate) can be used in related research in the field of life sciences. Its product number is T35630 and CAS number is 148556-27-8.
价 格:¥电议型 号:T35630产 地:中国大陆
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T35573Adenosine 5’-methylenediphosphate (hydrate);Adenosine 5’-methylenediphosphate (hydrate)Adenosine 5’m
Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or adenosine 5’-triphosphate but not adenosine in VA-13 human fibroblasts when used at a concentration of 100 μM. Adenosine 5’-methylenediphosphate reduces proliferation of U138MG glioma cells, as well as inhibits the invasion and migration of MHCC97H hepatocellular carcinoma (HCC)
价 格:¥电议型 号:T35573产 地:中国大陆
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T35571Adenosine 3’-monophosphate (sodium salt hydrate);Adenosine 3’-monophosphate (sodium salt hydrate)Ade
Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .
价 格:¥电议型 号:T35571产 地:中国大陆
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T35567BIX01294 (hydrochloride hydrate)BIX01294 (hydrochloride hydrate)BIX-01294 (hydrochloride hydrate)|||
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294 (hydrochloride hydrate) is a selective inhibitor of G9a HMTase (IC50 = 1.7 μM). It less effectively inhibits the HMTase G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other
价 格:¥电议型 号:T35567产 地:中国大陆
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T35538HPI-1 (hydrate);HPI-1 (hydrate)HPI-1 hydrate;HPI-1 hydrate
HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss of Suppressor of Fused or by Gli overexpression, suggesting action at posttranslational modification of Gli protein or at the interaction of Gli with a co-factor.1HPI-1 (hydrate) also inhibits signaling through the oncogenic Smoothened (Smo) mutant SmoM2 in neuron precursors, prev
价 格:¥电议型 号:T35538产 地:中国大陆
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T35416α-D-Glucose-1-phosphate (sodium salt hydrate);α-D-Glucose-1-phosphate (sodium salt hydrate)α-D-Gluco
α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2α-D-Glucose-1-phosphate can be formed during glycogen breakdownviaphosphorolytic cleavage of glycogen by glycogen phosphorylase.1It can be converted to glucose-6-phosphate by phosphoglucomutase. α-D-Glucose-1-phosphate is combined with CTP by α-D-glucose-1-phosphate cytidylyltransferase to form CDP-glucose in the first step of CDP-
价 格:¥电议型 号:T35416产 地:中国大陆
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T35415α-D-Glucose-1,6-bisphosphate (potassium salt hydrate);α-D-Glucose-1,6-bisphosphate (potassium salt h
α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism.
价 格:¥电议型 号:T35415产 地:中国大陆
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T35414α-Cyclodextrin (hydrate);α-Cyclodextrin (hydrate)α-Cyclodextrin (hydrate)
α-Cyclodextrin (α-CD) is a saccharide comprised of six glucose subunits linked by α-1,4 bonds, which results in a cone-shaped molecule.1It contains a hydrophobic interior and hydrophilic exterior, which allow it to form inclusion complexes with wide variety of molecules, conferring enhanced solubility and stabilization to the molecules. α-CD has commonly been used in the separation and purification of chemicals on an industrial scale.1,2Formulations containing α-CD have been used in the pharmace
价 格:¥电议型 号:T35414产 地:中国大陆
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T35375Zinc acetate dihydrateZinc acetate dihydrateAcetic acid zinc salt dihydrate|||Dicarbomethoxyzinc dih
Zinc acetate dihydrate (Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate) 通过靶向逆转录酶的锌促进杀菌剂凝胶的抗病毒活性。
价 格:¥电议型 号:T35375产 地:中国大陆
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T35369L(+)-Monosodium glutamate monohydrate;L(+)-Monosodium glutamate monohydrateL(+)-Monosodium glutamate
L(+)-Monosodium glutamate monohydrate (MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate)是一种广泛使用的营养添加剂和调味剂。L(+)-Monosodium glutamate monohydrate 可导致氧化应激介导的 DNA 损伤和细胞凋亡。
价 格:¥电议型 号:T35369产 地:中国大陆
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T35350Calcium gluconate monohydrate;Calcium gluconate monohydrateCalciofon|||Calcium gluconate anhydrous||
Calcium gluconate (Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen)是维持正常神经、肌肉和心脏功能所必需的元素或矿物质。葡萄糖钙可维持体内钙平衡,口服可阻止骨质疏松。
价 格:¥电议型 号:T35350产 地:中国大陆
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T35339Mometasone Furoate HydrateMometasone Furoate HydrateSCH 32088 hydrate|||Mometasone Furoate Hydrate
Mometasone Furoate (SCH 32088) Hydrate 是一种具有抗炎活性的合成糖皮质激素。
价 格:¥电议型 号:T35339产 地:中国大陆
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T34832Tezampanel hydrate;化合物 T34832LY293558|||NGX 424|||NGX424|||LY-293558|||NGX-424|||LY 293558;LY293558|
Tezampanel is used for the treatment of migraine, neuropathic pain.
价 格:¥电议型 号:T34832产 地:中国大陆
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T34610Semapimod hydrochloride dihydrate;化合物 T34610Semapimod hydrochloride dihydrate
Semapimod hydrochloride dihydrate is a biochemical.
价 格:¥电议型 号:T34610产 地:中国大陆
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T34265LRaunescine monoacetate monohydrate;化合物 T34265LRaunescine monoacetate monohydrate
Raunescine monoacetate monohydrate is a biochemical.
价 格:¥电议型 号:T34265L产 地:中国大陆
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T34265Raunescine monohydrate;化合物 T34265Raunescine monohydrate
Raunescine monohydrate is a biochemical.
价 格:¥电议型 号:T34265产 地:中国大陆