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T6274RO4929097；化合物RO4929097RG-4733；RG-4733
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
价 格：￥电议型 号：T6274产 地：中国大陆
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T62576Darglitazone Sodium；化合物 Darglitazone SodiumDarglitazone Sodium
Darglitazone Sodium is a thiazolidinedione, a selective, orally active PPAR-γ (peroxisome proliferator-activated receptor) agonist, which can be used in the study of type II diabetes as it effectively controls glucose and lipid metabolism.
价 格：￥电议型 号：T62576产 地：中国大陆
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T6254Idasanutlin；依达奴林RG7388|||Ro 5503781；RG7388|||Ro 5503781|||依达奴林
Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
价 格：￥电议型 号：T6254产 地：中国大陆
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T6252Ipatasertib；帕他色替GDC-0068|||RG7440；GDC-0068|||RG7440|||帕他色替
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
价 格：￥电议型 号：T6252产 地：中国大陆
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T62464Bz-D-Arg-pNA hydrochloride；化合物 Bz-D-Arg-pNA hydrochlorideBz-D-Arg-pNA hydrochloride
Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.
价 格：￥电议型 号：T62464产 地：中国大陆
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T6242Rupatadine Fumarate；富马酸卢帕他定Rinialer|||Rupafin|||Alergoliber；富马酸卢帕他定|||Rinialer|||Rupafin|||Alergolib
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
价 格：￥电议型 号：T6242产 地：中国大陆
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T62091Anti-hyperglycemic agent-1；化合物 Anti-hyperglycemic agent-1Anti-hyperglycemic agent-1
Anti-hyperglycemic agent 1 is a potent inhibitor of alpha-glucosidase (IC50: 0.53 μM). anti-Hyperglycemic agent 1 can be used to study diabetes.
价 格：￥电议型 号：T62091产 地：中国大陆
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T61786Selnoflast；塞诺司特RG 6418|||RO-7486967；RG 6418|||RO-7486967
Selnoflast (example 6) is a NLRP3 inhibitor[1].
价 格：￥电议型 号：T61786产 地：中国大陆
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T61336Numidargistat dihydrochloride；化合物 Numidargistat dihydrochlorideNumidargistat dihydrochloride
Numidargistat dihydrochloride (CB-1158) is a highly potent and orally active chemical compound that effectively inhibits arginase. It exhibits IC50 values of 86 nM and 296 nM for recombinant human arginase 1 and 2, respectively. Numidargistat dihydrochloride contributes to immuno-oncology, making it a valuable agent in the field [1].
价 格：￥电议型 号：T61336产 地：中国大陆
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T61332MRGPRX4 modulator-1；化合物 MRGPRX4 modulator-1MRGPRX4 modulator-1
MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases including itch, pain, and autoimmune disorders [1].
价 格：￥电议型 号：T61332产 地：中国大陆
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T6120Pralatrexate；普拉曲沙Folotyn|||10-Propargyl-10-deazaaminopterin；Folotyn|||10-炔丙基-10-去氮杂氨基蝶呤|||10-Proparg
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
价 格：￥电议型 号：T6120产 地：中国大陆
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T61183MRGPRX4 modulator-2；化合物 MRGPRX4 modulator-2MRGPRX4 modulator-2
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson´s Syndrome, and various chronic itch conditions is notable [1].
价 格：￥电议型 号：T61183产 地：中国大陆
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T61126Antibacterial synergist 1；化合物 Antibacterial synergist 1Antibacterial synergist 1
Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 of 4.5 μM. Antibacterial synergist 1 shows promise in the research of P. aeruginosa infections [1].
价 格：￥电议型 号：T61126产 地：中国大陆
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T61085TGP-377/421；化合物TGP-377/421Targapre-miR-377/421；Targapre-miR-377/421
TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.
价 格：￥电议型 号：T61085产 地：中国大陆
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T61062ERGi-USU-6 mesylate；化合物 ERGi-USU-6 mesylateERGi-USU-6 mesylate
ERGi-USU-6 (mesylate) is a new selective ERG positive prostate cancer inhibitor with an IC50 value of 0.089 μM that is an ERGi-USU-6 salt derivative.
价 格：￥电议型 号：T61062产 地：中国大陆
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T60870BRG1-IN-1；化合物 BRG1-IN-1BRG1-IN-1
BRG1-IN-1 (Compound 11d) is a potent BRG1 inhibitor with better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the subcutaneous GBM tumors growth[1].
价 格：￥电议型 号：T60870产 地：中国大陆
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T60598Thunbergol；化合物 ThunbergolThunbergol
Thunbergol (Isocembrol) (Compound 17) is a potent inhibitor of TNF-α (IC 50 = 7.2 μM) [1].
价 格：￥电议型 号：T60598产 地：中国大陆
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T60497MRGPRX1 agonist 3；化合物 MRGPRX1 agonist 3MRGPRX1 agonist 3
MRGPRX1 agonist 3 (compound 1f) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC50 of 0.22 μM. MRGPRX1 agonist 3 can be used for neuropathic pain research[1].
价 格：￥电议型 号：T60497产 地：中国大陆
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T60466MRGPRX1 agonist 2；化合物 MRGPRX1 agonist 2MRGPRX1 agonist 2
MRGPRX1 agonist 2 (compound 1a) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC 50 value of 0.48 μM. MRGPRX1 agonist 2 has the potential to be used in neuropathic pain research [1].
价 格：￥电议型 号：T60466产 地：中国大陆
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T6025Danoprevir；丹诺普韦R7227|||ITMN-191|||RG7227|||RO5190591；R7227|||丹诺普韦|||ITMN-191|||RG7227|||RO5190591
Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).
价 格：￥电议型 号：T6025产 地：中国大陆
