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T40151Thalidomide-5-propargyne-NH2 hydrochloride;Thalidomide-5-propargyne-NH2 hydrochlorideThalidomide-5-p
Thalidomide-5-propargyne-NH2 hydrochloride is a cereblon ligand derived from Thalidomide that is utilized in the recruitment of CRBN protein. It can be linked to the protein ligand through a linker to produce PROTACs, which are compounds used for protein degradation.
价 格:¥电议型 号:T40151产 地:中国大陆
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T40139H-Asn-Arg-OH;H-Asn-Arg-OHH-Asn-Arg-OH
H-Asn-Arg-OH is used for the solid-phase peptide synthesis.
价 格:¥电议型 号:T40139产 地:中国大陆
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T4008Metergoline;甲麦角林Methergoline|||Liserdol;甲麦角林|||Methergoline|||Liserdol
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder therapy.
价 格:¥电议型 号:T4008产 地:中国大陆
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T3S0364L-Arginine;L-精氨酸L-Arg|||(S)-(+)-Arginine;L-精氨酸|||L-Arg|||(S)-(+)-Arginine
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway. 4. A combination of oral L-citrulline and L-Arginine effectively and rapidly augments NO-dependent responses at the acute stage.
价 格:¥电议型 号:T3S0364产 地:中国大陆
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T39939Propargyl-PEG10-alcohol;Propargyl-PEG10-alcoholPropargyl-PEG10-alcohol;Propargyl-PEG10-alcohol
Propargyl-PEG10-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39939产 地:中国大陆
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T39932ARG1-IN-1ARG1-IN-1ARG1-IN-1
ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.
价 格:¥电议型 号:T39932产 地:中国大陆
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T39880Propargyl-Tos;Propargyl-TosPropargyl-Tos
Propargyl-Tos is a cleavable linker vital in ADC synthesis. Propargyl-Tos joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T39880产 地:中国大陆
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T39849Propargite;炔螨特Propargite
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] .
价 格:¥电议型 号:T39849产 地:中国大陆
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T39801Azido-PEG12-propargyl;Azido-PEG12-propargylAzido-PEG12-propargyl;Azido-PEG12-propargyl
Azido-PEG12-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39801产 地:中国大陆
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T39766Nor-NOHA monoacetate;nor-NOHA醋酸盐Nor NOHA monoacetate|||Nω-Hydroxy-nor-L-arginine monoacetate;Nor NOH
nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat hepatic arginase and inhibits the hydrolysis of L-arginine, which can be used to study cardiovascular and obstructive airway diseases.
价 格:¥电议型 号:T39766产 地:中国大陆
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T39712RGLS4326RGLS4326RG4326|||RGLS4326
RGLS4326 (RG4326) is a short oligonucleotide inhibitor of microRNA-17 (miR-17), with a pioneering role in its class. This compound, with a research focus on autosomal dominant polycystic kidney disease (ADPKD), effectively suppresses the activity of miR-17 in HeLa cells, displaying an EC50 value of 28.3 nM.
价 格:¥电议型 号:T39712产 地:中国大陆
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T39678Multitarget AD inhibitor-1;Multitarget AD inhibitor-1Multitarget AD inhibitor-1
Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 μM and 1.55 μM for human BuChE (hBuChE) and equine serum BuChE (eqBuChE), respectively. Additionally, it exhibits inhibitory activity towards β-secretase (IC50 value of 41.60 μM), amyloid β aggregation (IC50 value of 3.09 μM), and tau aggregation. As a diphenylpropylamine derivative, Multitarget AD inhibitor-1 holds promise for research pertaining to the multifunctional, d
价 格:¥电议型 号:T39678产 地:中国大陆
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T39655Arg-Gly-Asp-Cys TFA;Arg-Gly-Asp-Cys TFAArg-Gly-Asp-Cys TFA
Arg-Gly-Asp-Cys TFA serves as the binding motif through which fibronectin interacts with cell adhesion molecules. This compound has the ability to hinder platelet aggregation and fibrinogen binding.
价 格:¥电议型 号:T39655产 地:中国大陆
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T39633Navocaftor;NavocaftorGLPG 3067|||ABBV-3067;GLPG 3067|||ABBV-3067
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
价 格:¥电议型 号:T39633产 地:中国大陆
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T39617Propargyl-PEG5-PFP ester;Propargyl-PEG5-PFP esterPropargyl-PEG5-PFP ester;Propargyl-PEG5-PFP ester
Propargyl-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39617产 地:中国大陆
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T39616Propargyl-PEG3-PFP ester;Propargyl-PEG3-PFP esterPropargyl-PEG3-PFP ester;Propargyl-PEG3-PFP ester
Propargyl-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39616产 地:中国大陆
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T3957Farampator;化合物FarampatorOrg24448|||CX-691;Org24448|||CX-691
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
价 格:¥电议型 号:T3957产 地:中国大陆
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T39540Propargyl-O-C1-amido-PEG3-C2-NHS ester;Propargyl-O-C1-amido-PEG3-C2-NHS esterPropargyl-O-C1-amido-PE
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3-unit polyethylene glycol (PEG) linker employed for the chemical synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T39540产 地:中国大陆
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T3947Nonanoic acid;壬酸pelargonic acid|||Nonoic acid;pelargonic acid|||Nonoic acid|||壬酸
Nonanoic acid (Nonoic acid) is a fatty acid which occurs naturally as esters are the oil of pelargonium. Synthetic esters, such as methyl nonanoate, are used as flavorings. Pelargonic acid is an organic compound composed of a nine-carbon chain terminating in a carboxylic acid. It is an oily liquid with an unpleasant, rancid odor. It is nearly insoluble in water, but well soluble in chloroform and ether.
价 格:¥电议型 号:T3947产 地:中国大陆
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T39441L-Arginine-15N4 hydrochlorideL-Arginine-15N4 hydrochlorideL-Arginine-15N4 hydrochloride|||(S)-(+)-Ar
L-Arginine-15N4 ((S)-(+)-Arginine-15N4) hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished.
价 格:¥电议型 号:T39441产 地:中国大陆