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T3705GDC0084；化合物GDC-0084GDC-0084|||RG7666|||GDC 0084；GDC-0084|||RG7666|||GDC 0084
GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity. GDC0084 (RG7666) specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in the inhibition of both cell growth and survival in susceptible tumor cell populations.
价 格：￥电议型 号：T3705产 地：中国大陆
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T37038Betulinic Acid propargyl ester；Betulinic Acid propargyl esterBetulinic Acid propargyl ester
Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives.
价 格：￥电议型 号：T37038产 地：中国大陆
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T37034H-Gly-Arg-pNA dihydrochloride；H-Gly-Arg-pNA二盐酸盐H-Gly-Arg-Pna 2HCl；H-Gly-Arg-Pna 2HCl
H-Gly-Arg-pNA dihydrochloride (H-Gly-Arg-Pna 2HCl) belongs to the class of peptides that bind to 1,2 thrombin and can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.
价 格：￥电议型 号：T37034产 地：中国大陆
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T37033H-D-Pro-Phe-Arg-pNA . 2 HCl；H-D-Pro-Phe-Arg-pNA . 2 HClH-D-Pro-Phe-Arg-pNA . 2 HCl
pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9.
价 格：￥电议型 号：T37033产 地：中国大陆
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T36440GS-441524 tris-isobutyryl ester；GS-441524 tris-isobutyryl esterGS-441524 tris-isobutyryl ester
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 μM.
价 格：￥电议型 号：T36440产 地：中国大陆
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T36436Spergualin trihydrochloride；Spergualin trihydrochlorideSpergualin trihydrochloride
Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1].
价 格：￥电议型 号：T36436产 地：中国大陆
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T36417Nargenicin；NargenicinAntibiotic 47444；Antibiotic 47444
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (
价 格：￥电议型 号：T36417产 地：中国大陆
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T363682H-Cho-Arg (trifluoroacetate salt)；2H-Cho-Arg (trifluoroacetate salt)2H-Cho-Arg (trifluoroacetate sa
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and t
价 格：￥电议型 号：T36368产 地：中国大陆
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T36365KAPA (hydrochloride)KAPA (hydrochloride)KAPA (hydrochloride)|||7-keto-8-Aminopelargomic Acid
Biotin is a growth factor that plays an important role in numerous reactions that are critical to microorganisms, plants, and animals. Biotin has a strong affinity for the protein avidin, a trait that has been utilized for many assay reporter applications. KAPA is a key intermediate in the biotin biosynthetic pathway.[1]
价 格：￥电议型 号：T36365产 地：中国大陆
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T36359Dios-Arg (trifluoroacetate salt)Dios-Arg (trifluoroacetate salt)DiosArg (trifluoroacetate salt)|||Di
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4. Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav
价 格：￥电议型 号：T36359产 地：中国大陆
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T36350Cho-Arg (trifluoroacetate salt)Cho-Arg (trifluoroacetate salt)ChoArg (trifluoroacetate salt)|||Cho A
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav
价 格：￥电议型 号：T36350产 地：中国大陆
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T36340Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)；Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gl
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fluorescence measurement of Abz (ex = 320 nm; em = 420 nm).
价 格：￥电议型 号：T36340产 地：中国大陆
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T36339Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp；Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnpAbz-Ala-P
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fluorescence measurement of Abz (ex = 320 nm; em = 420 nm).
价 格：￥电议型 号：T36339产 地：中国大陆
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T36241Arecaidine propargyl ester (hydrobromide)Arecaidine propargyl ester (hydrobromide)Arecaidine proparg
Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 μM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 μM.2Arecai
价 格：￥电议型 号：T36241产 地：中国大陆
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T3623Cobimetinib；考比替尼RG7420|||XL518|||GDC-0973；可美替尼|||考比替尼|||RG7420|||XL518|||GDC-0973
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) phosphorylation and activation and decreased tumor cell proliferation.
价 格：￥电议型 号：T3623产 地：中国大陆
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T3612Carbocisteine；羧甲司坦Carbocysteine|||Broncodeterge|||Mucodyne|||S-Carboxymethyl-L-cysteine；Carbocystein
Carbocisteine (Mucodyne) is commonly used as an anti-infective nasal spray with mucolytic and expectorant effects.
价 格：￥电议型 号：T3612产 地：中国大陆
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T36079Tripelargonin；化合物 TripelargoninTripelargonin
Tripelargonin is a triacylglycerol that contains nonanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass.1 Tripelargonin increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in newborn rhesus monkeys.2
价 格：￥电议型 号：T36079产 地：中国大陆
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T35932Gly-Arg-AMC (hydrochloride)；Gly-Arg-AMC (hydrochloride)Gly-Arg-AMC (hydrochloride)
Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
价 格：￥电议型 号：T35932产 地：中国大陆
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T35886L-hydroxy Arginine (acetate)；L-hydroxy Arginine (acetate)L-hydroxy Arginine (acetate)
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.
价 格：￥电议型 号：T35886产 地：中国大陆
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T35666PRGL493；化合物PRGL493PRGL493
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 μM. PRGL493 (5 μM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg.
价 格：￥电议型 号：T35666产 地：中国大陆
