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产品数：86101
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T15612JH-VIII-157-02CD246,Cluster of differentiation 246,inhibit,Anaplastic lymphoma kinase,Anaplastic lym
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
价 格：￥电议型 号：T15612产 地：中国大陆
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T60156PBRM1-BD2-IN-2PBRM1BD2IN2
PBRM1-BD2-IN-2 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-2 has binding affinity and inhibitory activity for PBRM1-BD2 with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. PBRM1-BD2-IN-2 can be used for the research of cancer.
价 格：￥电议型 号：T60156产 地：中国大陆
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T13456(S)-Willardiine
(S)-Willardiine is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).
价 格：￥电议型 号：T13456产 地：中国大陆
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T15608Jarin-1Jarin 1,Jarin1
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
价 格：￥电议型 号：T15608产 地：中国大陆
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TQ0082AticaprantCERC 501,inhibit,LY2456302,Opioid Receptor,Aticaprant,Inhibitor,CERC501,LY 2456302
Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).
价 格：￥电议型 号：TQ0082产 地：中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格：￥电议型 号：T6561产 地：中国大陆
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T64337PF-04745637PF04745637,Inhibitor,bowel,TRPA1,disease,inhibit,respiratory,PF-04745637,Transient recept
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
价 格：￥电议型 号：T64337产 地：中国大陆
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T15615JND3229JND-3229,JND3229
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
价 格：￥电议型 号：T15615产 地：中国大陆
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TP1561123C4Inhibitor,123C-4,123C4,Ephrin Receptor,inhibit
123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase?EPHA4 (Ki=0.65 μM)[1].
价 格：￥电议型 号：TP1561产 地：中国大陆
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TP1543LG280-9 acetate(156761-76-1 free base)G280 9 acetate(156761 76 1 free base),G-280-9 acetate(156761-76
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.
价 格：￥电议型 号：TP1543L产 地：中国大陆
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TN1563Dehydropachymic acidAutophagy,inhibit,Inhibitor,Dehydropachymic acid
Dehydropachymic acid shows antiinflammatory activity.
价 格：￥电议型 号：TN1563产 地：中国大陆
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TP1238LACTH 1-14 acetate(25696-21-3 free base)ACTH 1 14 acetate(25696 21 3 free base),ACTH 114 acetate(2569
ACTH (1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress.
价 格：￥电议型 号：TP1238L产 地：中国大陆
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T9756AZD-9574PPAR,Peroxisome proliferator-activated receptors,breast cancer,inhibit,AZD-9574,HRR,HRR-defi
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.
价 格：￥电议型 号：T9756产 地：中国大陆
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TJS0856Dalbergininhibit,Dalbergin,Inhibitor
1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin prevents some effects of photoaging and maintain skin integrity by regulating the degradation of the extracellular matrix proteins.
价 格：￥电议型 号：TJS0856产 地：中国大陆
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T6568LicofeloneLicofelone,Lipoxygenase,ML 3000,LOX,Apoptosis,COX,Inhibitor,inhibit,ML3000,Cyclooxygenase
Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase).
价 格：￥电议型 号：T6568产 地：中国大陆
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T6S1256Ruscogenininhibit,Ruscogenin,Inhibitor,NOD-like Receptor (NLR)
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.
价 格：￥电议型 号：T6S1256产 地：中国大陆
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T6569Mimosineanti-fibrosis,Fe(III),Anti-cancer,herbicida,inhibit,Apoptosis,iron-binding,insecticidal,Mimo
L-Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
价 格：￥电议型 号：T6569产 地：中国大陆
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T6457CTEPMetabotropic glutamate receptors,CTEP,RO4956371,inhibit,mGluR,Inhibitor,RO-4956371
CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.
价 格：￥电议型 号：T6457产 地：中国大陆
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T9568SGC-SMARCA-BRDVIIIEpigenetic Reader Domain,adipogenesis,SMARCA2/4,inhibit,PB1,SGCSMARCABRDVIII,Inhib
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
价 格：￥电议型 号：T9568产 地：中国大陆
