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T8973HS-1793HIF-1α,Inhibitor,MCF-7,HS 1793,breast cancer,inhibit,ERK,HCT116,resveratrol,VEGF,Apoptosis,HS
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model
价 格:¥电议型 号:T8973产 地:中国大陆
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T7727Se-Methylselenocysteinecaspase-3,A253,neck,SKOV-33,FaDu,Apoptosis,chemopreventive,cancer,cells,Se-Me
Se-Methylselenocysteine is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.
价 格:¥电议型 号:T7727产 地:中国大陆
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T8742G5-7antiangiogenic,inhibit,Apoptosis,JAK,Glioma,G-5-7,cycle,G5 7,phase,G57,STAT3,cell,Inhibitor,EGFR
JAK2 inhibitor G5-7 is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study
价 格:¥电议型 号:T8742产 地:中国大陆
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T8934(6R)-FR054inhibit,ERS,(6R)-FR054,Inhibitor,(6R) FR054,Apoptosis,TNBC,(6R)-FR-054,cancer,breast,(6R)F
FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
价 格:¥电议型 号:T8934产 地:中国大陆
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TN1493Chrysosplenol Dcancer,Apoptosis,inhibit,ERK1/2,Inhibitor,antitrypanosomal,breast,Chrysosplenol D,ant
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
价 格:¥电议型 号:TN1493产 地:中国大陆
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TN11468-?Prenylnaringenininhibit,Apoptosis,8?Prenylnaringenin,8-?Prenylnaringenin,Inhibitor,8 ?Prenylnarin
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
价 格:¥电议型 号:TN1146产 地:中国大陆
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T7127DC260126stress,DC260126,DC-260126,FFAR,Inhibitor,insulin,inhibit,secretion,Apoptosis,DC 260126,Free
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
价 格:¥电议型 号:T7127产 地:中国大陆
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TN2080Pinoresinolapoptotic,sensitizer,Pinoresinol,caterpillar,inhibit,cancer,Apoptosis,Inhibitor,lignol,gl
Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activa
价 格:¥电议型 号:TN2080产 地:中国大陆
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T9541CTBHATs,Inhibitor,neurons,CTB,Apoptosis,MCF-7 cell,cancer,potent,HAT,autophagic flux,inhibit,Histone
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.
价 格:¥电议型 号:T9541产 地:中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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T13867RH01386RH 01386,βTC6 cells,RH01386,RH-01386,inhibit,Apoptosis,Inhibitor,type 2 diabetes,β cell
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.
价 格:¥电议型 号:T13867产 地:中国大陆
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TQ0060LY2857785Cyclin dependent kinase,LY 2857785,CDK,Apoptosis,LY2857785,Inhibitor,inhibit,LY-2857785
LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).
价 格:¥电议型 号:TQ0060产 地:中国大陆
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T6919OmaveloxoloneInhibitor,Omaveloxolone,Apoptosis,RTA 408,RTA408,ERIS,STING,inhibit,Stimulator of Inter
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
价 格:¥电议型 号:T6919产 地:中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格:¥电议型 号:T6481产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T6473DioscinAutophagy,CCRIS-4123,CCRIS4123,Apoptosis,Dioscin,inhibit,Inhibitor
Dioscin is a saponin with antitumor activities.
价 格:¥电议型 号:T6473产 地:中国大陆
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T8464RA-9Unfolded,RA-9,cancer,RA 9,DUBs,Inhibitor,Apoptosis,Response,Deubiquitinase,cells,inhibit,Protein
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
价 格:¥电议型 号:T8464产 地:中国大陆
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T2085PQ401MCF-7,PQ401,IGF-1R,cells,breast,PQ-401,PQ 401,inhibit,caspase,Apoptosis,autophosphorylation,can
PQ401 suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
价 格:¥电议型 号:T2085产 地:中国大陆
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T9243PFI-90antitumor,Inhibitor,PFI 90,differentiation,PAX3-FOXO1,demethylase,PFI-90,apoptosis,histone,His
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the potential for the antitumor activity. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.
价 格:¥电议型 号:T9243产 地:中国大陆
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T8838CCI-007CCI 007,MLL-r,CALM-AF10,HOXA9,MEIS1,Apoptosis,CMYC,CCI-007,SET-NUP214,inhibit,Inhibitor,CCI00
CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485
价 格:¥电议型 号:T8838产 地:中国大陆