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T22612BMY-14802 hydrochloride
BMY-14802 hydrochloride is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A.
价 格:¥电议型 号:T22612产 地:中国大陆
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T7512BMS-191011Potassium Channel,rodent models of stroke,Panc-1,neuroprotective activity,inhibit,IGR39,BM
BMS-191011 is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
价 格:¥电议型 号:T7512产 地:中国大陆
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T9636DalpiciclibMCF7,BT-474/T,Cyclin dependent kinase,Eca 109,MCF7/TR,and KYSE-510 ESCC,SHR6390,Inhibitor
Dalpiciclib is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4?nM and 9.9?nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
价 格:¥电议型 号:T9636产 地:中国大陆
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T22192BMS 195614
BMS 195614 is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.
价 格:¥电议型 号:T22192产 地:中国大陆
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T8716physalin Fcytokine,PBMC,physalin F,HTLV-1,infection,inflammatory,Inhibitor,Apoptosis,immunomodulator
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection
价 格:¥电议型 号:T8716产 地:中国大陆
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T8390CefazolinBacterial,Cefazolin,C8-B4,post-operative cognitive dysfunction,Antibiotic,PBMC,Inhibitor,an
Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.
价 格:¥电议型 号:T8390产 地:中国大陆
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T8882Vodobatinibmyeloid,Inhibitor,inhibit,Vodobatinib,chronic,K0706,Bcr-Abl,K 0706,Bcr-Abl1,leukemia,TKI
Vodobatinib is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
价 格:¥电议型 号:T8882产 地:中国大陆
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T8342BRD9876Kinesin,microtubule,Inhibitor,BRD9876,BMSC,multiple,myeloma,α4-α6,CD34,tyrosine,ATP,MM1S,G2/M
BRD9876 is a selective inhibitor of MM1S growth.
价 格:¥电议型 号:T8342产 地:中国大陆
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T36964BML-259BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent k
BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
价 格:¥电议型 号:T36964产 地:中国大陆
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TQ0306MLN120BMLN120B,ML120B,Inhibitor,I kappa B kinase,inhibit,IKK,IκB kinase,MLN-120B
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
价 格:¥电议型 号:TQ0306产 地:中国大陆
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T9220Naftopidil hydrochlorideBM-15275,BM15275,canine,prostatic,Naftopidil,prostate,hyperplasia,inhibit,In
Naftopidil hydrochloride is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respectively. Naftopidil hydrochloride has antiproliferative effects.
价 格:¥电议型 号:T9220产 地:中国大陆
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T8542BMS-345541 hydrochlorideI kappa B kinase,BMS345541 hydrochloride,Inhibitor,BMS345541,BMS-345541,BMS
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).
价 格:¥电议型 号:T8542产 地:中国大陆
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T30544BMS-919373
BMS-919373 is a potassium channel Kv1.5 (KCNA5) inhibitor for atrial fibrillation and acute coronary syndrome.
价 格:¥电议型 号:T30544产 地:中国大陆
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T6419BMS-536924inhibit,Insulin Receptor,Inhibitor,Apoptosis,insulin-like,BMS536924,BMS-536924,IGF-1R,canc
BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
价 格:¥电议型 号:T6419产 地:中国大陆
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T9125Tolebrutinibmultiple,PRN 2246,SAR-442168,inhibit,Bruton tyrosine kinase,Tolebrutinib,sclerosis,Bruto
Tolebrutinib is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).
价 格:¥电议型 号:T9125产 地:中国大陆
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T2545Lomitapide MesylateInhibitor,Lomitapide,Lomitapide Mesylate,AEGR-733,inhibit,AEGR 733,BMS-201038,AEG
Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
价 格:¥电议型 号:T2545产 地:中国大陆
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T11961MBM-55SMBM 55S,MBM55S
MBM-55S is an effective inhibitor of Nek2 with an IC50 of 1 nM. MBM-55S indecus cell cycle arrest and apoptosis thereby inhibiting the proliferation of cancer cells. MBM-55S shows antitumor activities.
价 格:¥电议型 号:T11961产 地:中国大陆
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T6326BMS-345541BMS345541;IKK Inhibitor III;BMS 345541;BMS-345541 free base
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
价 格:¥电议型 号:T6326产 地:中国大陆
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T6297Alvespimycin hydrochlorideAlvespimycin (17-DMAG) HCl;NSC 707545;17-DMAG hydrochloride;KOS-1022;BMS 8
17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
价 格:¥电议型 号:T6297产 地:中国大陆
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T6267Lomitapide洛美他派;AEGR-733;BMS-201038
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) i
价 格:¥电议型 号:T6267产 地:中国大陆