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T1713IBMXIBMX,3-异丁基-1-甲基黄嘌呤;3-Isobutyl-1-methylxanthine;Methylisobutylxanthine;Isobutylmethylxanthine;1-M
IBMX is a pan-phosphodiesterase (PDE) inhibitor (IC50s: 6.5/26.3/31.7 μM for PDE3/PDE4/PDE5).
价 格:¥电议型 号:T1713产 地:中国大陆
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T16754RIPGBM
RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).
价 格:¥电议型 号:T16754产 地:中国大陆
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T1615Irbesartan厄贝沙坦;SR-47436;BMS-186295
Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T15352FTBMT
FTBMT is a selective GPR52 agonist (EC50: 75 nM) and it also has antipsychotic and procognitive properties.
价 格:¥电议型 号:T15352产 地:中国大陆
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T15286FlindokalnerBMS-204352
Flindokalner is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner displays a negat
价 格:¥电议型 号:T15286产 地:中国大陆
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T14692BMX-IN-1BMX kinase inhibitor
BMX-IN-1 is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec acti
价 格:¥电议型 号:T14692产 地:中国大陆
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T14687DeucravacitinibBMS-986165
BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) a
价 格:¥电议型 号:T14687产 地:中国大陆
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T14685BMS-986158
BMS-986158 is a potent BET inhibitor with IC50s of 6.6 and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.
价 格:¥电议型 号:T14685产 地:中国大陆
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T1448LDasatinib monohydrateBMS-354825 Monohydrate;达沙替尼
Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for
价 格:¥电议型 号:T1448L产 地:中国大陆
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T1448Dasatinib达沙替尼;BMS-354825
Dasatinib is a potent inhibitor of the Bcr-Abl and Src family (IC50s: 0.6, 0.8, 79 and 37 nM for Abl, Src, c-Kit, and c-KitD816V, respectively).
价 格:¥电议型 号:T1448产 地:中国大陆
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T1425Pemirolast potassium吡嘧司特钾;TWT-8152;BMY 26517
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells.
价 格:¥电议型 号:T1425产 地:中国大陆
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T1404Stavudine司他夫定;Sanilvudine;BMY-27857;NSC 163661;d4T
Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
价 格:¥电议型 号:T1404产 地:中国大陆
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T13584BMVC-8C3O
BMVC-8C3O is a DNA G-quadruplexe (G4) ligand, can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s.
价 格:¥电议型 号:T13584产 地:中国大陆
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T13306LVapreotide acetateRC-160 acetate;BMY-41606 acetate;醋酸伐普肽
Vapreotide acetate is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).
价 格:¥电议型 号:T13306L产 地:中国大陆
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T1293Gatifloxacin加替沙星;CG5501;AM-1155;BMS-206584;BMS 206584-01;PD 135432
Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
价 格:¥电议型 号:T1293产 地:中国大陆
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T11960MBM-55
MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice. MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM.
价 格:¥电议型 号:T11960产 地:中国大陆
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T1185RofecoxibMK 966;MK-0966;罗非昔布;罗非考昔
Rofecoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyret
价 格:¥电议型 号:T1185产 地:中国大陆
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T11740DelcasertibBMS-875944;KAI-9803
Delcasertib is a potent and selective inhibitor of δ-protein kinase C (δPKC).
价 格:¥电议型 号:T11740产 地:中国大陆
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T10573BMT-145027
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
价 格:¥电议型 号:T10573产 地:中国大陆
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T10570Fostemsavir TrisBMS-663068 Tris
Fostemsavir Tris is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
价 格:¥电议型 号:T10570产 地:中国大陆