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T38694Sp-8-CPT-cAMPS；Sp-8-CPT-cAMPSSp-8-CPT-cAMPS
Sp-8-CPT-cAMPS is a powerful and specific cAMP analog that activates cAMP-dependent protein kinase A (PKA I and PKA II) selectively and effectively. It exhibits a 153-fold preference for site A of RI over site A of RII, and a 59-fold preference for site B of RII over site B of RI.
价 格：￥电议型 号：T38694产 地：中国大陆
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T36678Rp-8-CPT-cAMPS sodium；Rp-8-CPT-Cyclic AMP (sodium salt)Rp-8-CPT-cAMPS sodium
Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II.2 By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.[2],[3]
价 格：￥电议型 号：T36678产 地：中国大陆
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T2764(S)-10-Hydroxycamptothecin；10-羟基喜树碱10-Hydroxycamptothecin|||10-HCPT；10-羟喜树碱|||10-羟基喜树碱|||10-Hydroxyc
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
价 格：￥电议型 号：T2764产 地：中国大陆
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T270768-Cyclopentyl-1,3-dimethylxanthineA1受体拮抗剂,CPTCPT|||A1受体拮抗剂,CPT
8-Cyclopentyl-1,3-dimethylxanthine (CPT)?is a potent antagonist of adenosine A1 receptor.
价 格：￥电议型 号：T27076产 地：中国大陆
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T24610Pegamotecan；化合物PegamotecanProthecan|||PEG-camptothecin|||PEG-beta-CPT；Prothecan|||PEG-camptothecin||
Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell lung and pancreatic cancers.
价 格：￥电议型 号：T24610产 地：中国大陆
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T22698TLR3-IN-1；化合物CU CPT 4aCU CPT 4a；CU CPT 4a
TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.
价 格：￥电议型 号：T22698产 地：中国大陆
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T22693CPTH2 (hydrochloride) (357649-93-5 free base)；化合物 T22693CPTH2 (hydrochloride)；CPTH2 (hydrochloride)
CPTH2 is an inhibitor of the HAT activity of Gcn5.
价 格：￥电议型 号：T22693产 地：中国大陆
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T225368-pCPT-2-O-Me-cAMP-AM；化合物 T225368 pCPT 2 O Me cAMP AM|||8-pCPT-2-O-Me-cAMP-AM|||8pCPT2OMecAMPAM；8 pC
Epac activator
价 格：￥电议型 号：T22536产 地：中国大陆
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T220148-CPT-2Me-cAMP, sodium salt；化合物 T220148-CPT-2Me-cAMP, sodium salt
8-CPT-2Me-cAMP sodium is a sodium salt compound that selectively activates exchange proteins activated by cAMP (Epac). These Epac proteins are cAMP-sensitive guanine nucleotide exchange factors (GEFs) responsible for activating small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium specifically activates Epac1 with an EC50 value of 2.2 μM, while showing no activation of PKA with an EC50 value greater than 10 μM [1]. Additionally, 8-CPT-2Me-cAMP sodium stimulates the Epac-mediated release of calcium
价 格：￥电议型 号：T22014产 地：中国大陆
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T217058-CPT-Cyclic AMP (sodium salt)；化合物 T217058-CPT-Cyclic AMP (sodium salt)
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium functions dually as a selective activator of cyclic AMP-dependent protein kinase (PKA) and as a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA), demonstrating an inhibitory concentration (IC 50) of 0.9 μM. Additionally, this compound inhibits PDE III and PDE IV, while significantly activating Epac, showcasing its diverse pharmacological activities [1] [2].
价 格：￥电议型 号：T21705产 地：中国大陆
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T15020CU-CPT22；化合物CU-CPT22CU-CPT22
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 μM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 μM).
价 格：￥电议型 号：T15020产 地：中国大陆
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T1123Camptothecin喜树碱NSC-100880|||Campathecin|||喜树碱|||(S)-(+)-Camptothecin|||CPT
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
价 格：￥电议型 号：T1123产 地：中国大陆
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T10899CU-CPT17e；化合物CU-CPT17eCU-CPT17e
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
价 格：￥电议型 号：T10899产 地：中国大陆
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T0486LIrinotecan Hydrochloride；伊立替康盐酸盐Camptothecin 11 hydrochloride|||CPT-11 hydrochloride；盐酸伊立替康|||伊立替康盐酸
Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replicat
价 格：￥电议型 号：T0486L产 地：中国大陆
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T0486Irinotecan hydrochloride trihydrate；盐酸伊立替康三水合物Irinotecan HCl Trihydrate|||CPT-11 HCl Trihydrate；Irin
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.
价 格：￥电议型 号：T0486产 地：中国大陆
