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T0097LPazopanibPazopanib,GW786034,
Pazopanib, a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result in inhibition of angiogenesis in tumors in whic
价 格:¥电议型 号:T0097L产 地:美洲
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T11518GW274150 phosphateGW274150 phosphate
GW274150 phosphate displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation.?GW274150 phosphate is a potent, selective, orally a
价 格:¥电议型 号:T11518产 地:美洲
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T11518LGW274150GW274150
GW274150 shows less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 is a selective and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM).
价 格:¥电议型 号:T11518L产 地:美洲
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T11520GW806742XGW806742X
GW806742X has activity against VEGFR2.?GW806742X is a Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor which binds the MLKL pseudokinase domain with a Kd value of 9.3 μM and has anti-necroptosis activity.?
价 格:¥电议型 号:T11520产 地:美洲
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T11521GW 766994GW 766994,GW 994,
GW 766994 has has the potential for asthma and eosinophilic bronchitis treatment.GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist.
价 格:¥电议型 号:T11521产 地:美洲
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T11525GW311616GW311616
GW-311616 is a orally bioavailable,potent , long duration and selective human neutrophil elastase (HNE) inhibitor with IC50 value of 22 nM and Ki value of 0.31 nM.
价 格:¥电议型 号:T11525产 地:美洲
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T11525LGW311616 hydrochlorideGW311616 hydrochloride,GW311616A,
GW-311616 is a potent, long duration,orally bioavailable and selective human neutrophil elastase (HNE) inhibitor with IC50 value of 22 nM and Ki value of 0.31 nM.
价 格:¥电议型 号:T11525L产 地:美洲
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T12683Radafaxine hydrochlorideRadafaxine hydrochloride,GW-353162A,BW-306U
Radafaxine hydrochloride is an inhibitor of DAT and NET transporters, and nAChR family modulator.
价 格:¥电议型 号:T12683产 地:美洲
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T12720PrinoxodanPrinoxodan,RGW2938,
Prinoxodan is an inhibitor of phosphodiesterase.
价 格:¥电议型 号:T12720产 地:美洲
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T12850DilmapimodDilmapimod,SB-681323,GW 681323
Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
价 格:¥电议型 号:T12850产 地:美洲
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T12970SolabegronSolabegron,GW 427353,
Solabegron is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome.
价 格:¥电议型 号:T12970产 地:美洲
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T13335WEHI-345 alogWEHI-345 alog,WEHI-345 analog,
WEHI-345 analog is an inhibitor of Src.
价 格:¥电议型 号:T13335产 地:美洲
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T15689L-798106L-798106,CM9,GW671021
L-798106 is an effective and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM). It also has micromolar activities at EP4, EP1, and EP2 receptors (Ki: 916 nM, >5000 nM and >5000 nM at EP4, EP1 and EP2, respectively).
价 格:¥电议型 号:T15689产 地:美洲
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T1781GW 9508GW 9508
GW9508 is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
价 格:¥电议型 号:T1781产 地:美洲
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T1800GW 788388GW 788388
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
价 格:¥电议型 号:T1800产 地:美洲
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T1978GW 627368XGW 627368X,GW627368,
GW627368X is a novel, potent and selective antagonist of prostanoid EP4 receptor.
价 格:¥电议型 号:T1978产 地:美洲
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T2233GW 4064GW 4064
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
价 格:¥电议型 号:T2233产 地:美洲
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T2260GW 9662GW 9662,TIMTEC-BB SBB006523,
GW9662 is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.
价 格:¥电议型 号:T2260产 地:美洲
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T2277LosmapimodLosmapimod,GW856553X,SB856553
Losmapimod (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
价 格:¥电议型 号:T2277产 地:美洲