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T79861EGFR/ErbB-2 inhibitor-1;EGFR/ErbB-2抑制剂1EGFR/ErbB-2 inhibitor-1
EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.
价 格:¥电议型 号:T79861产 地:中国大陆
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T79686FGFR1 inhibitor-10;化合物 FGFR1 inhibitor-10FGFR1 inhibitor-10
FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation. This compound demonstrates anti-angiogenic and anti-invasion properties, as well as a significant anti-tumor effect [1].
价 格:¥电议型 号:T79686产 地:中国大陆
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T79258sEH inhibitor-16;化合物 sEH inhibitor-16sEH inhibitor-16
sEH Inhibitor-16, a potent soluble epoxide hydrolase (sEH) inhibitor, exhibits an IC50 of 2 nM. It diminishes inflammatory damage associated with cerulein-induced acute pancreatitis (AP) in mice, making it suitable for inflammation and immunology research [1].
价 格:¥电议型 号:T79258产 地:中国大陆
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T79212mTOR inhibitor-12;化合物 mTOR inhibitor-12mTOR inhibitor-12
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to central nervous system (CNS) diseases [1].
价 格:¥电议型 号:T79212产 地:中国大陆
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T79211mTOR inhibitor-11;化合物 mTOR inhibitor-11mTOR inhibitor-11
mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 of 21 nM for pS6. It also exhibits inhibitory activity against pCHK1 and PDE4D with IC50 values of 17.2 μM and 17.0 μM, respectively. This compound is utilized in CNS disease research [1].
价 格:¥电议型 号:T79211产 地:中国大陆
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T79094Bromodomain inhibitor-12 (edisylate);化合物 Bromodomain inhibitor-12 (edisylate)Bromodomain inhibitor-1
Bromodomain Inhibitor-12 Edisylate (example 303) serves as a bromodomain inhibitor applicable to autoimmune and inflammatory disease research [1].
价 格:¥电议型 号:T79094产 地:中国大陆
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T79093Bromodomain inhibitor-12;化合物 Bromodomain inhibitor-12Bromodomain inhibitor-12
Bromodomain Inhibitor-12 (example 303) is a research compound utilized in the study of autoimmune and inflammatory diseases [1].
价 格:¥电议型 号:T79093产 地:中国大陆
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T74501NHEJ inhibitor-1;化合物 NHEJ inhibitor-1NHEJ inhibitor-1
NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-small cell lung cancer (NSCLC). It achieves this by inhibiting the damage repair proteins Ku70 and Rad51, thus re-sensitizing tumors to Cisplatin. Additionally, this compound prompts the generation of reactive oxygen species (ROS) and reduces mitochondrial membrane potential (MMP)
价 格:¥电议型 号:T74501产 地:中国大陆
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T74211HIV-1 inhibitor-12;化合物 HIV-1 inhibitor-12HIV-1 inhibitor-12
HIV-1 inhibitor-12 is a potent inhibitor that targets the HIV-1 capsid protein, effectively preventing its polymerization with an inhibition concentration (IC 50) of 9 nM.
价 格:¥电议型 号:T74211产 地:中国大陆
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T74210HIV-1 inhibitor-11;化合物 HIV-1 inhibitor-11HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.
价 格:¥电议型 号:T74210产 地:中国大陆
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T73830BRD4 Inhibitor-16;化合物 BRD4 Inhibitor-16BRD4 Inhibitor-16
BRD4 Inhibitor-16 (Compound 4) is a potent inhibitor of bromodomain 4 (BRD4), whose overexpression is closely correlated with various human cancers through the regulation of histone post-translational modifications. It serves as a valuable tool for explorative studies focused on BRD4 inhibition, facilitating an enhanced comprehension of BRD4 inhibitor release-related information [1].
价 格:¥电议型 号:T73830产 地:中国大陆
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T72698sEH inhibitor-14;化合物 sEH inhibitor-14sEH inhibitor-14
sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with an IC50 value of 0.39 nM.
价 格:¥电议型 号:T72698产 地:中国大陆
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T72695UCK2 Inhibitor-1;化合物 UCK2 Inhibitor-1UCK2 Inhibitor-1
UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 ?M [1] .
价 格:¥电议型 号:T72695产 地:中国大陆
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T72638iNOS inhibitor-10;化合物 iNOS inhibitor-10iNOS inhibitor-10
iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].
价 格:¥电议型 号:T72638产 地:中国大陆
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T7261Grp94 Inhibitor-1;化合物Grp94 Inhibitor-1Grp94 Inhibitor-1
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
价 格:¥电议型 号:T7261产 地:中国大陆
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T72599KRAS inhibitor-11;化合物 KRAS inhibitor-11KRAS inhibitor-11
KRAS inhibitor-11 is a KRAS inhibitor [1] .
价 格:¥电议型 号:T72599产 地:中国大陆
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T72534HIV-1 inhibitor-10;化合物 HIV-1 inhibitor-10HIV-1 inhibitor-10
HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.
价 格:¥电议型 号:T72534产 地:中国大陆
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T72521Efflux inhibitor-1;化合物 Efflux inhibitor-1Efflux inhibitor-1
Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC 50 s of 0.45 μM and 2.17 μM, respectively .
价 格:¥电议型 号:T72521产 地:中国大陆
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T72380PI3K/mTOR Inhibitor-13;化合物 PI3K/mTOR Inhibitor-13PI3K/mTOR Inhibitor-13
PI3K/mTOR Inhibitor-13, an orally active dual inhibitor targeting phosphoinositol 3-kinase (PI3K) and mTOR kinase, holds potential for treating sexual diseases, solid tumors, and idiopathic pulmonary fibrosis (IPF).
价 格:¥电议型 号:T72380产 地:中国大陆
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T72374PI3K/mTOR Inhibitor-12;化合物 PI3K/mTOR Inhibitor-12PI3K/mTOR Inhibitor-12
PI3K/mTOR Inhibitor-12, a potent and selective orally active inhibitor, exhibits IC50 values of 0.06 nM for PI3Kα and 3.12 nM for mTOR, indicating significant antitumor activity with reduced liver toxicity [1].
价 格:¥电议型 号:T72374产 地:中国大陆