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T40248JNK3 inhibitor-1JNK3 inhibitor-1JNK3 inhibitor-1
JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 μM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent oral bioavailability and the ability to efficiently penetrate the brain.
价 格:¥电议型 号:T40248产 地:中国大陆
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T40206MEK4 inhibitor-1MEK4 inhibitor-1MEK4 inhibitor-1
MEK4 inhibitor-1 is a newly developed compound specifically designed to inhibit the activity of MEK4, a key enzyme involved in pancreatic adenocarcinoma, with an IC 50 value of 61 nM.
价 格:¥电议型 号:T40206产 地:中国大陆
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T40083GLUT inhibitor-1;GLUT抑制剂1GLUT inhibitor-1
GLUT inhibitor-1 is an orally active GLUT inhibitor with IC50 s of 242 nM and 179 nM for GLUT1 and GLUT3. GLUT inhibitor-1 can be used in studies about cancers and autoimmune diseases.
价 格:¥电议型 号:T40083产 地:中国大陆
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T39741SSAO inhibitor-1;SSAO inhibitor-1SSAO inhibitor-1
SSAO inhibitor-1 is a compound that acts as an inhibitor of semicarbazide-sensitive amine oxidase (SSAO). It exhibits anti-inflammatory properties and is commonly employed in research pertaining to liver diseases.
价 格:¥电议型 号:T39741产 地:中国大陆
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T39678Multitarget AD inhibitor-1;Multitarget AD inhibitor-1Multitarget AD inhibitor-1
Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 μM and 1.55 μM for human BuChE (hBuChE) and equine serum BuChE (eqBuChE), respectively. Additionally, it exhibits inhibitory activity towards β-secretase (IC50 value of 41.60 μM), amyloid β aggregation (IC50 value of 3.09 μM), and tau aggregation. As a diphenylpropylamine derivative, Multitarget AD inhibitor-1 holds promise for research pertaining to the multifunctional, d
价 格:¥电议型 号:T39678产 地:中国大陆
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T38931Calpain Inhibitor-1;Calpain Inhibitor-1Calpain Inhibitor-1
Calpain Inhibitor-1 (compound 36) is a highly potent and selective inhibitor of Calpain 1 (Cal1), which is a cysteine protease. It exhibits an IC50 value of 100 nM and a Ki value of 2.89 μM.
价 格:¥电议型 号:T38931产 地:中国大陆
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T38367CAY10640;化合物CAY10640sEH inhibitor-1;sEH inhibitor-1
CAY10640 (sEH inhibitor-1) is a potent, orally active, water-soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in humans and mice with IC50s of 0.4 and 5.3 nM, respectively.
价 格:¥电议型 号:T38367产 地:中国大陆
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T37426FIIN-1;化合物FIIN-1FGFR irreversible inhibitor-1;FGFR irreversible inhibitor-1
FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2, FGFR3, FGFR4, with IC50 of 9.2, 6.2, 11.9 and 189 nM. FIIN-1 inhibited FGFR1, FGFR2, FGFR3 and FGFR4, with IC50s of 9.2, 6.2, 11.9 and 189 nM, respectively.
价 格:¥电议型 号:T37426产 地:中国大陆
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T36761KRAS inhibitor-10;KRAS inhibitor-10KRAS inhibitor-10
KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer research, specifically in pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer. KRAS inhibitor-10 is classified as a tetrahydroisoquinoline compound. Its inhibitory properties provide valuable insights and potential therapeutic applications in the field of
价 格:¥电议型 号:T36761产 地:中国大陆
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T36527IL-4-inhibitor-1;化合物IL-4-inhibitor-1IL-4-inhibitor-1
IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.
价 格:¥电议型 号:T36527产 地:中国大陆
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T35566RBPJ Inhibitor-1;化合物RBPJ Inhibitor-1RIN1;RIN1
RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell proliferation[1].
价 格:¥电议型 号:T35566产 地:中国大陆
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T28788SK-216;化合物 T28788SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor;SK216.Plasminogen activat
SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the degree of bleomycin-induced pulmonary fibrosis in mice.
价 格:¥电议型 号:T28788产 地:中国大陆
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T28286P2Y1-IN-16;化合物 T28286P2Y1 inhibitor-16|||P2Y1 inhibitor 16;P2Y1 inhibitor-16|||P2Y1 inhibitor 16
P2Y1-IN-16 is a novel antagonist of P2Y1.
价 格:¥电议型 号:T28286产 地:中国大陆
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T28219NusB-NusE interaction inhibitor-1;化合物 T28219NusB-NusE interaction inhibitor-1
NusB-NusE interaction inhibitor-1 is a modulator of the NusB-NusE interaction.
价 格:¥电议型 号:T28219产 地:中国大陆
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T28148NDM-1 inhibitor-1;化合物 T28148NDM-1 inhibitor-1
NDM-1 inhibitor-1 is an inhibitor of new delhi metallo-β-lactamase-1 (NDM-1).
价 格:¥电议型 号:T28148产 地:中国大陆
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T28089mPGES-1 Inhibitor-1;mPGES-1 抑制剂1mPGES-1 Inhibitor-1
mPGES-1 Inhibitor-1 is a novel selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) with anti-inflammatory and analgesic activity for the study of acute liver injury.
价 格:¥电议型 号:T28089产 地:中国大陆
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T28045miR-21 Inhibitor-1;化合物 T28045miR-21 Inhibitor-1
miR-21 Inhibitor-1 is a microRNA-21 (miR-21) inhibitor.
价 格:¥电议型 号:T28045产 地:中国大陆
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T27997MDK-3345;化合物 T27997MDK 3345|||Mcl-1 Inhibitor11|||Mcl-1 Inhibitor 11|||Mcl-1 Inhibitor-11;MDK 3345||
MDK-3345 is a reversible covalent inhibitor for Mcl-1.
价 格:¥电议型 号:T27997产 地:中国大陆
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T27194DNA Primase Inhibitor-13;化合物 T27194DNA Primase Inhibitor-13
DNA Primase Inhibitor-13 is a novel inhibitor of DNA primase.
价 格:¥电议型 号:T27194产 地:中国大陆
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T26282TNIK-IN-1;化合物 T26282TNIK-inhibitor-1|||TNIK inhibitor 1;TNIK-inhibitor-1|||TNIK inhibitor 1
TNIK-IN-1 is an inhibitor of Traf2- and Nck-interacting kinase (TNIK).
价 格:¥电议型 号:T26282产 地:中国大陆