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  • T6186TRAM-34TRAM-34,TRAM34,TRAM 34

    TRAM-34(Kd=20 nM),an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1),does not block cytochrome P450. The selective activity of TRAM-34 is 200 to 1500-fold than other ion channels.

    价 格：￥电议型 号：T6186产 地：美洲

  • T8531m-3M3FBS2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺

    m-3M3FBS is a phospholipase C (PLC) activator.

    价 格：￥电议型 号：T8531产 地：中国大陆

  • T8511TM38837；化合物TM38837TM38837

    TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.

    价 格：￥电议型 号：T8511产 地：中国大陆

  • T8426Encequidar；化合物EncequidarHM30181|||HM30181A；HM30181|||HM30181A

    Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor.

    价 格：￥电议型 号：T8426产 地：中国大陆

  • T83630STM3006；化合物 STM3006STM3006

    STM3006 is an orally active, selective and and potent METTL3 inhibitor with antitumor activity for the study of acute myeloid leukemia (AML).

    价 格：￥电议型 号：T83630产 地：中国大陆

  • T82436Etigilimab；化合物 EtigilimabOMP-313M32；OMP-313M32

    Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, inhibits TIGIT from interacting with PVR (CD155; poliovirus receptor) and suppresses subsequent signaling, resulting in target cell death [1].

    价 格：￥电议型 号：T82436产 地：中国大陆

  • T82006JM3A；化合物 JM3AJM3A

    JM3A, a highly specific peptoid reagent, selectively targets cell surface vimentin (CSV) on early lung cancer cells undergoing tumor transformation. By conjugating with fluorophores [1], JM3A detects and stains CSV, enabling identification of these cells.

    价 格：￥电议型 号：T82006产 地：中国大陆

  • T81892M351-110；化合物 M351-110M351-110

    M351-110 is an agonist of the V-domain Ig suppressor of T cell activation (VISTA) designed for oncological studies [1].

    价 格：￥电议型 号：T81892产 地：中国大陆

  • T81559Pam3-Cys-Ala-Gly；化合物 Pam3-Cys-Ala-GlyPam3-Cys-Ala-Gly

    Pam3-Cys-Ala-Gly, a synthetic bacterial lipopeptide, serves as a powerful activator of both macrophages and B cells [1].

    价 格：￥电议型 号：T81559产 地：中国大陆

  • T81098Stapokibart；化合物 StapokibartCM310；CM310

    Stapokibart (CM310), a humanized monoclonal antibody, selectively binds to IL-4Rα, inhibiting the cytokines IL-4 and IL-13 from interacting with their shared co-receptor subunit, IL-4Rα. This compound demonstrates cross-species reactivity by interacting with IL-4Rα in humans, cynomolgus monkeys, and rats [1].

    价 格：￥电议型 号：T81098产 地：中国大陆

  • T80954TREM-1 inhibitory peptide M3；化合物 TREM-1 inhibitory peptide M3TREM-1 inhibitory peptide M3

    TREM-1 inhibitory peptide M3 acts as a ligand-dependent antagonist of TREM-1, capable of suppressing systemic and pulmonary pro-inflammatory cytokine and chemokine production, thereby mitigating acute lung injury [1].

    价 格：￥电议型 号：T80954产 地：中国大陆

  • T80519m3-Huwentoxin IV；化合物 m3-Huwentoxin IVm3-HwTx-IV；m3-HwTx-IV

    m3-Huwentoxin IV (m3-HwTx-IV) is a potent inhibitor of sodium channels (NaV), exhibiting half-maximal inhibitory concentrations (IC50s) of 3.3 nM for hNaV1.7, 6.8 nM for hNaV1.6, 7.2 nM for hNaV1.3, 8.4 nM for hNaV1.1, 11.9 nM for hNaV1.2, and 369 nM for hNaV1.4 in the QPatch assay. It also dose-dependently alleviates spontaneous pain in a rodent model when induced by the NaV1.7 activator OD1 [1].

    价 格：￥电议型 号：T80519产 地：中国大陆

  • T80429π-TRTX-Hm3a；化合物 π-TRTX-Hm3aπ-TRTX-Hm3a

    π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion channel 1a (ASIC1a) in a pH-dependent manner, with an inhibitory concentration half-max (IC50) of 1-2 nM, and also potentiates the activity of acid-sensing ion channel 1b (ASIC1b) with an effective concentration half-max (EC50) of 46.5 nM [1].

    价 格：￥电议型 号：T80429产 地：中国大陆

  • T80238NODAGA-LM3 TFA；化合物 NODAGA-LM3 TFANODAGA-LM3 TFA

    NODAGA-LM3 TFA, a SSTR2 antagonist, can be radiolabeled with ^68Ga for PET imaging applications, particularly in the visualization of SSTR-positive paragangliomas [1] [2].

    价 格：￥电议型 号：T80238产 地：中国大陆

  • T80237NODAGA-LM3；化合物 NODAGA-LM3NODAGA-LM3

    NODAGA-LM3, when labeled with ^68Ga, serves as a PET imaging agent. As an SSTR2 antagonist, ^68Ga-NODAGA-LM3 is utilized for the visualization of SSTR-positive paragangliomas [1] [2].

    价 格：￥电议型 号：T80237产 地：中国大陆

  • T80155DOTA-LM3；化合物 DOTA-LM3DOTA-LM3

    DOTA-LM3 is a somatostatin receptor (SSTR) antagonist, with LM3 denoting the peptide sequence p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2. It is utilized in the isotopic labeling of tumors for in vivo tracing, notably with 177Lu-DOTA-LM3 and 68Ga-DOTA-LM3. The derivative 68Ga-DOTA-LM3 exhibits promising biodistribution, high tumor uptake, efficient tumor retention, and minimal safety concerns, while 177Lu-DOTA-LM3 is applied in research on DOTATOC-negative liver metas

    价 格：￥电议型 号：T80155产 地：中国大陆

  • T79618M3/PDE4 modulator-1；化合物 M3/PDE4 modulator-1M3/PDE4 modulator-1

    M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor. When administered intravenously at concentrations ranging from 10 to 1000 nM/kg, this compound effectively diminishes eosinophil influx into cysts within the OVA rat model [1].

    价 格：￥电议型 号：T79618产 地：中国大陆

  • T78121SSM3 tetraTFA hydrate；化合物 SSM3 tetraTFA hydrateSSM3 tetraTFA hydrate

    SSM3 tetraTFA hydrate is a potent synthetic inhibitor of furin, exhibiting an EC50 of 54 nM and a Ki of 12 nM. It effectively inhibits the furin-dependent cell surface processing of anthrax protective antigen-83 in vitro [1] [2].

    价 格：￥电议型 号：T78121产 地：中国大陆

  • T78110DOTA-LM3 TFA；化合物 DOTA-LM3 TFADOTA-LM3 TFA

    DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2. It is effectively used in tracing tumors in vivo through isotopic labeling, examples being 177Lu-DOTA-LM3 TFA and 68Ga-DOTA-LM3 TFA. The 68Ga-labeled compound demonstrates favorable biodistribution, high tumor uptake, good tumor retention, and minimal safety concerns. Meanwhile, the 177Lu-labeled variant is utilized in research targeting

    价 格：￥电议型 号：T78110产 地：中国大陆

  • T77713BTM-3566；化合物BTM-3566BTM 3566|||BTM3566；BTM 3566|||BTM3566

    BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to study DLBCL.

    价 格：￥电议型 号：T77713产 地：中国大陆

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