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  • T76724Nemolizumab；奈莫利珠单抗CIM331；CIM331

    Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be used to study atopic dermatitis with pruritus.

    价 格：￥电议型 号：T76724产 地：中国大陆

  • T74916ODN M362；化合物 ODN M362ODN M362

    ODN M362, a class C oligodeoxynucleotide and TLR-9 agonist, serves as a vaccine adjuvant and induces apoptosis in cancer cells [1] [2].

    价 格：￥电议型 号：T74916产 地：中国大陆

  • T7359CAY10471 Racemate；化合物CAY10471 RacemateTM30089 Racemate；TM30089 Racemate|||3-[[(4-氟苯基)磺酰基]甲基氨基]-1,2,3

    CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectively)

    价 格：￥电议型 号：T7359产 地：中国大陆

  • T73559M3913；化合物 M3913M3913

    M3913 is an antitumor compound with antiproliferative activity against cancer cells.

    价 格：￥电议型 号：T73559产 地：中国大陆

  • T73546WM382；化合物 WM382WM382

    WM382, a potent orally active dual plasmepsin IX/X (PMIX/X) inhibitor, demonstrates significant efficacy across multiple stages of the malaria parasite life cycle with IC50 values of 1.4 nM and 0.03 nM, respectively. It also exhibits an excellent resistance profile.

    价 格：￥电议型 号：T73546产 地：中国大陆

  • T71949CM304；化合物 CM304CM304

    CM304 is a highly selective sigma-1 receptor antagonist.

    价 格：￥电议型 号：T71949产 地：中国大陆

  • T71650BDM31369；化合物 BDM31369BDM31369

    BDM31369 is an activator of ethionamide.

    价 格：￥电议型 号：T71650产 地：中国大陆

  • T71649BDM31343；化合物 BDM31343BDM31343

    BDM31343 is an EthR inhibitor, boosting antituberculous activity of ethionamide.

    价 格：￥电议型 号：T71649产 地：中国大陆

  • T70873M3541；化合物M3541M3541

    M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells.

    价 格：￥电议型 号：T70873产 地：中国大陆

  • T69366CM39；化合物 CM39CM39

    CM39 is an ALDH inhibitor. Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer stem-like cells and in chemoresistance.

    价 格：￥电议型 号：T69366产 地：中国大陆

  • T68492AM 374；化合物AM374HDSF|||Hexadecanesulfonyl fluoride；HDSF|||Hexadecanesulfonyl fluoride

    AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM. This compound is potentially applicable in neurological disease research.

    价 格：￥电议型 号：T68492产 地：中国大陆

  • T68339SSM3 TFA；化合物 SSM3 TFASSM3 TFA

    SSM3 TFA is a potent furin inhibitor, blocking furin-dependent cell surface processing of anthrax protective antigen-83 in vitro..

    价 格：￥电议型 号：T68339产 地：中国大陆

  • T67835LKM38；化合物LKM38LKM38

    LKM38, a novel diazolidinyl cholesterol probe, is a promising cholesterol mimetic.LKM38 both maintains cholesterol-resistant cell growth and appropriately regulates key cholesterol homeostatic pathways.LKM38 can be a powerful tool for studying cholesterol protein interactions and trafficking.

    价 格：￥电议型 号：T67835产 地：中国大陆

  • T6454CORM-3；(OC-6-44)-三羰基氯(甘氨酸基)钌CORM3；CORM3|||(OC-6-44)-三羰基氯(甘氨酸基)钌

    CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.

    价 格：￥电议型 号：T6454产 地：中国大陆

  • T62149ALM301；化合物 ALM301ALM301

    ALM301 is a highly specific, orally active AKT inhibitor that acts on AKT1 (IC50: 0.13 μM), AKT2 (IC50: 0.09 μM) and AKT3 (IC50: 2.75 μM). ALM301 inhibits AKT phosphorylation in vitro and has a regulatory effect on downstream signalling. ALM301 exhibits inhibitory effects on cancer cell proliferation and tumor growth.

    价 格：￥电议型 号：T62149产 地：中国大陆

  • T6186TRAM-34；化合物TRAM34Triarylmethane-34|||TRAM 34；Triarylmethane-34|||TRAM 34

    TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34(TRAM 34) is 200 to 1500-fold than other ion channels.

    价 格：￥电议型 号：T6186产 地：中国大陆

  • T61846CM398；化合物 CM398CM398

    CM398 is an orally active chemical compound that acts as a highly selective ligand for the sigma-2 receptor (K i =0.43 nM), demonstrating a significant ratio of selectivity between sigma-1 and sigma-2 receptors (1000-fold). Moreover, CM398 exhibits notable affinity towards dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). In addition, CM398 has shown promising efficacy as an anti-inflammatory analgesic in a mouse model of inflammatory pain induced by formalin [1].

    价 格：￥电议型 号：T61846产 地：中国大陆

  • T6145ZM39923 hydrochloride化合物ZM 39923 HClJAK3 Inhibitor IV|||ZM 39923 HCl

    ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

    价 格：￥电议型 号：T6145产 地：中国大陆

  • T60085MM3122；化合物MM3122GTPL11533|||MM-3122|||Ac-GQFR-kbt；GTPL11533|||MM-3122|||Ac-GQFR-kbt

    MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.

    价 格：￥电议型 号：T60085产 地：中国大陆

  • T5091FM-381；化合物FM381FM381；FM381

    FM381 is a potent covalent reversible inhibitor of JAK3. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.

    价 格：￥电议型 号：T5091产 地：中国大陆

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