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T6278SotrastaurinSotrastaurin,AEB071,
Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
价 格:¥电议型 号:T6278产 地:美洲
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T6280EnzastaurinEnzastaurin,LY317615,
Enzastaurin (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.
价 格:¥电议型 号:T6280产 地:美洲
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T6405Bepotastine BesilateBepotastine Besilate,Bepotastine Beslilate,TAU 284
Bepotastine is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).
价 格:¥电议型 号:T6405产 地:美洲
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T83858Tauro-Obeticholic Acid sodium;化合物 Tauro-Obeticholic Acid sodiumTauro-6-Ethylchenodeoxycholic Acid|||
Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.
价 格:¥电议型 号:T83858产 地:中国大陆
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T81097Stauntoside M;化合物 Stauntoside MStauntoside M
Stauntoside M, a steroidal glycoside, is isolated from the roots of Cynanchum stauntonii [1].
价 格:¥电议型 号:T81097产 地:中国大陆
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T81031tau protein/α-synuclein-IN-1;化合物 tau protein/α-synuclein-IN-1tau protein/α-synuclein-IN-1
Tau protein/α-synuclein-IN-1 is a dual inhibitor that not only impedes tau protein and α-synuclein but also reduces the development of α-syn inclusions in M17D neuroblastoma cells, making it a useful agent in the study of Alzheimer´s disease [1].
价 格:¥电议型 号:T81031产 地:中国大陆
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T81030Tauro-β-muricholic acid;化合物 Tauro-β-muricholic acidTβMCA;TβMCA
Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic effects by inhibiting bile acid-induced hepatocellular apoptosis and preserving mitochondrial membrane potential [1] [2].
价 格:¥电议型 号:T81030产 地:中国大陆
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T8092Taurohyodeoxycholic acid sodium salt牛磺猪去氧胆酸钠Sodium taurohyodeoxycholate hydrate
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.
价 格:¥电议型 号:T8092产 地:中国大陆
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T79038Tau protein aggregation-IN-1;化合物 Tau protein aggregation-IN-1Tau protein aggregation-IN-1
Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer´s disease, dementia, Parkinson´s disease, Huntington´s disease, and prion-based spongiform encephalopathies [1].
价 格:¥电议型 号:T79038产 地:中国大陆
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T78173Aβ/tau aggregation-IN-3;化合物 Aβ/tau aggregation-IN-3Aβ/tau aggregation-IN-3
Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 ?M in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activity [1].
价 格:¥电议型 号:T78173产 地:中国大陆
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T77991Glutaurine TFA;化合物 Glutaurine TFALitoralon TFA;Litoralon TFA
Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in the study of antiepileptic and anti-amnesia treatments, as evidenced by references [1] [2] [3] [4].
价 格:¥电议型 号:T77991产 地:中国大陆
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T76661Acetyl-Tau Peptide (273-284) amide;化合物 Acetyl-Tau Peptide (273-284) amideAcetyl-Tau Peptide (273-284
Acetyl-Tau Peptide (273-284) amide, an acetylated fragment of the Tau peptide, acts as an inhibitor to prevent significant aggregation of Ac-Aβ(25–35)-NH2. Furthermore, it serves as a model for studying the cross-interaction between Aβ and Tau [1] [2].
价 格:¥电议型 号:T76661产 地:中国大陆
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T7533Taurolidine;牛磺罗定Taurolidine
Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.
价 格:¥电议型 号:T7533产 地:中国大陆
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T75319Taurodeoxycholic acid;牛磺异熊去氧胆酸Taurodeoxychloic acid;Taurodeoxychloic acid
Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic acid inhibits apoptosis by blocking calcium-mediated apoptotic pathways and by activation of caspase-12. Taurodeoxycholic acid has neuroprotective activity and has been used to study 3-nitropropionic acid-induced or stabilized hereditary Huntington´s chorea (HD).
价 格:¥电议型 号:T75319产 地:中国大陆
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T74811tau/Aβ40 aggregation-IN-1;化合物 tau/Aβ40 aggregation-IN-1tau/Aβ40 aggregation-IN-1
Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1].
价 格:¥电议型 号:T74811产 地:中国大陆
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T71853Enzastaurin HCl;化合物 Enzastaurin HClEnzastaurin HCl
Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
价 格:¥电议型 号:T71853产 地:中国大陆
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T69990Ruboxistaurin mesylate monohydrate;化合物 Ruboxistaurin mesylate monohydrateRuboxistaurin mesylate mono
Ruboxistaurin mesylate monohydrate is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
价 格:¥电议型 号:T69990产 地:中国大陆
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T6993Tauroursodeoxycholate sodium;牛磺熊去氧胆酸钠Sodium tauroursodeoxycholate|||Tauroursodeoxycholic acid sodium
Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
价 格:¥电议型 号:T6993产 地:中国大陆
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T69354Enzastaurin 2HCl;化合物 Enzastaurin 2HClEnzastaurin 2HCl
Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
价 格:¥电议型 号:T69354产 地:中国大陆
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T6680Staurosporine;星形孢菌素Antibiotic AM-2282|||AM-2282|||CGP 41251;Antibiotic AM-2282|||星形孢菌素|||AM-2282|||C
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
价 格:¥电议型 号:T6680产 地:中国大陆