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T65644N-Cyclohexyltaurine;化合物 N-CyclohexyltaurineN-Cyclohexyltaurine
N-Cyclohexyltaurine is a useful organic compound for research related to life sciences. The catalog number is T65644 and the CAS number is 103-47-9.
价 格:¥电议型 号:T65644产 地:中国大陆
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T64377AGI-41998 tautomers;AGI-41998互变异构体AGI-41998 tautomers
AGI-41998 tautomers is a tautomerism of pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]- is a S-adenosylmethionine synthase isoform type-2 inhibitor, IC50= 0.022μM.
价 格:¥电议型 号:T64377产 地:中国大陆
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T6405Bepotastine Besilate苯磺酸贝托司汀Talion|||TAU 284|||苯磺酸贝托司汀|||Bepreve|||Bepotastine Beslilate
Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).
价 格:¥电议型 号:T6405产 地:中国大陆
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T63793Tauro-ω-muricholic acid sodium;化合物 Tauro-ω-muricholic acid sodiumTauro-ω-muricholic acid sodium
Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin. Tauro-ω-muricholic acid sodium can be used as a serum marker for early onset neonatal sepsis (EOS) and biliary stasis.
价 格:¥电议型 号:T63793产 地:中国大陆
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T63481Tau-aggregation-IN-1;化合物 Tau-aggregation-IN-1Tau-aggregation-IN-1
Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).
价 格:¥电议型 号:T63481产 地:中国大陆
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T63013Ruboxistaurin;化合物 RuboxistaurinRuboxistaurin
Ruboxistaurin (LY333531) is a selective, orally active PKC beta inhibitor with a Ki value of 2 nM. Ruboxistaurin competitively inhibits PKC beta I (IC50: 4.7 nM) in an ATP-dependent manner. Ruboxistaurin is able to act on PKC beta II (IC50: 5.9 nM).
价 格:¥电议型 号:T63013产 地:中国大陆
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T62899Tau-aggregation and neuroinflammation-IN-1;Tau蛋白聚集体和神经炎症抑制剂1Tau-aggregation and neuroinflammation-IN
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflammation-IN-1 has anti-inflammatory activity and reduces NO release.Tau-aggregation and neuroinflammation-IN-1 has low cytotoxicity against LSP-stimulated BV2 cells.Tau-aggregation and neuroinflammation-IN-1 reverses okadaic acid-induced memory impairment in rats.
价 格:¥电议型 号:T62899产 地:中国大陆
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T6280Enzastaurin;恩扎妥林LY317615;LY317615|||恩扎妥林
Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.
价 格:¥电议型 号:T6280产 地:中国大陆
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T6278Sotrastaurin;索曲妥林AEB071;索曲妥林|||AEB071
Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
价 格:¥电议型 号:T6278产 地:中国大陆
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T5225Hypotaurine;亚牛磺酸2-Aminoethanesulfinic acid|||2-Aminoethylsulfinic acid;2-Aminoethanesulfinic acid|||
Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor.
价 格:¥电议型 号:T5225产 地:中国大陆
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T4727Taurolithocholic acid sodium salt;牛磺石胆酸钠Sodium taurolithocholate;牛磺石胆酸钠|||Sodium taurolithocholate
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
价 格:¥电议型 号:T4727产 地:中国大陆
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T40409Tau Peptide (275-305) (Repeat 2 domain);Tau Peptide (275-305) (Repeat 2 domain)Tau Peptide (275-305)
Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer´s tau peptide. Tau Peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.
价 格:¥电议型 号:T40409产 地:中国大陆
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T39781Aβ/tau aggregation-IN-1;Aβ/tau aggregation-IN-1Aβ/tau aggregation-IN-1
Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can penetrate the blood-brain barrier efficiently.
价 格:¥电议型 号:T39781产 地:中国大陆
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T39660Tau tracer 1;Tau tracer 1Tau tracer 1
Tau tracer 1 is a radiopharmaceutical agent designed specifically for visualizing Tau protein aggregates, commonly associated with neurodegenerative diseases. Its primary application lies in the diagnosis of these conditions.
价 格:¥电议型 号:T39660产 地:中国大陆
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T37846Taurohyocholic Acid (sodium salt);Taurohyocholic Acid (sodium salt)Taurohyocholic Acid (sodium salt)
Taurohyocholic acid (THCA) is a taurine-conjugated form of the porcine-specific primary bile acid hyocholic acid .1THCA inhibits precipitation of cholesterol crystals by stabilizing cholesterol in the liquid-crystalline phase.2It prevents cholestasis and cellular necrosis induced by taurolithocholic acid in isolated rat livers.3THCA levels are increased in the urine of patients with hepatitis B-induced cirrhosis.4
价 格:¥电议型 号:T37846产 地:中国大陆
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T37845Taurocholic Acid 3-sulfate (sodium salt);Taurocholic Acid 3-sulfate (sodium salt)Taurocholic Acid 3-
Taurocholic acid 3-sulfate (TCA3S) is a metabolite of the conjugated bile acid taurocholic acid .1Plasma levels of TCA3S are elevated in wild-type andSortilin 1(Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated inSort1knockout mice at 24 hours post-BDL.2
价 格:¥电议型 号:T37845产 地:中国大陆
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T37771Taurolithocholic Acid 3-sulfate (sodium salt)Taurolithocholic Acid 3-sulfate (sodium salt)Taurolitho
Taurolithocholic acid 3-sulfate (TLCA3S) is a metabolite of the conjugated bile acid taurolithocholic acid . TLCA3S has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models of bile acid infusion pancreatitis.
价 格:¥电议型 号:T37771产 地:中国大陆
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T37770Taurohyodeoxycholic acid;牛磺猪去氧胆酸Taurohyodeoxycholic acid
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi
价 格:¥电议型 号:T37770产 地:中国大陆
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T37416Tauro-α-muricholic Acid (sodium salt);Tauro-α-muricholic Acid (sodium salt)Tauro-α-muricholic Acid (
Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid . TαMCA is common in rodents but has also been found in small amounts in human serum.
价 格:¥电议型 号:T37416产 地:中国大陆
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T3689LRuboxistaurin mesylate;化合物 T3689LLY-333531|||LY333531|||LY 333531|||LY-333531 Mesylate;LY-333531|||L
Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
价 格:¥电议型 号:T3689L产 地:中国大陆