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T74536IDO/Tubulin-IN-2;化合物 IDO/Tubulin-IN-2IDO/Tubulin-IN-2
IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC50 values of 0.43, 0.036, 0.041, 0.095, and 1.04 μM. Additionally, IDO/Tubulin-IN-2 markedly enhances antitumor activity [1].
价 格:¥电议型 号:T74536产 地:中国大陆
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T73832Tubulin inhibitor 21;化合物 Tubulin inhibitor 21Tubulin inhibitor 21
Tubulin Inhibitor 21 (compound 6f), a hybrid based on chalcone and melatonin, exhibits potent tubulin inhibition properties. It demonstrates significant cytotoxic activity against SW480 cells (IC 50 =0.26?μM) while showing lesser effects on nonmalignant cells [1].
价 格:¥电议型 号:T73832产 地:中国大陆
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T72719Tubulin/MMP-IN-2;化合物 Tubulin/MMP-IN-2Tubulin/MMP-IN-2
Tubulin/MMP-IN-2, a dual inhibitor of tubulin and matrix metalloproteinases (MMPs), effectively inhibits tubulin polymerization and induces cell apoptosis. It demonstrates inhibitory activities against MMP-2, MMP-3, and MMP-9, with IC50 values of 24.95 μM, 31.60 μM, and 22.37 μM, respectively. This compound is utilized in cancer research.
价 格:¥电议型 号:T72719产 地:中国大陆
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T72676Tubulin/MMP-IN-1;化合物 Tubulin/MMP-IN-1Tubulin/MMP-IN-1
Tubulin/MMP-IN-1, a potent inhibitor of both tubulin and MMP, holds promise for cancer research. It effectively suppresses tubulin polymerization, induces G2/M phase cell cycle arrest, and promotes reactive oxidative stress (ROS) generation in HepG2 cells, ultimately triggering apoptosis via the mitochondrial-dependent apoptotic pathway.
价 格:¥电议型 号:T72676产 地:中国大陆
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T72503Antitubulin agent 1;化合物 Antitubulin agent 1Antitubulin agent 1
Antitubulin Agents-1, an antitubulin agent, disrupts microtubules (Microtubule/Tubulin) and enhances α-tubulin acetylation, exhibiting anticancer effects.
价 格:¥电议型 号:T72503产 地:中国大陆
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T72449Tubulin inhibitor 31;化合物 Tubulin inhibitor 31Tubulin inhibitor 31
Tubulin Inhibitor 31 is a potent compound with an inhibitory concentration (IC 50) of 4 ?M, demonstrating significant anti-proliferative activity and the ability to inhibit HUVEC migration.
价 格:¥电议型 号:T72449产 地:中国大陆
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T72445Tubulin inhibitor 30;化合物 Tubulin inhibitor 30Tubulin inhibitor 30
Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.
价 格:¥电议型 号:T72445产 地:中国大陆
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T72169Tubulin polymerization-IN-40;化合物 Tubulin polymerization-IN-40Tubulin polymerization-IN-40
Tubulin Polymerization-IN-40 is an acridane-based inhibitor that potently disrupts tubulin polymerization, exhibiting an IC50 of 1.5 μM. It halts cancer cell progression at the G2/M phase, triggers apoptosis, and possesses anti-cancer properties along with immunopotentiating effects [1].
价 格:¥电议型 号:T72169产 地:中国大陆
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T72167Tubulin polymerization-IN-39;化合物 Tubulin polymerization-IN-39Tubulin polymerization-IN-39
Tubulin polymerization-IN-39, a tubulin polymerization inhibitor with an IC50 of 4.9 μM, targets the colchicine-binding site to hinder tubulin polymerization. This compound effectively suppresses cancer cell proliferation.
价 格:¥电议型 号:T72167产 地:中国大陆
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T67935Tubulin inhibitor 11;Tubulin抑制剂11Tubulin inhibitor 11
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis.
价 格:¥电议型 号:T67935产 地:中国大陆
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T63849Tubulin polymerization-IN-34;化合物 Tubulin polymerization-IN-34Tubulin polymerization-IN-34
Tubulin polymerization-IN-34 is an inhibitor of [1,2] oxazolylisoindole microtubulin polymerization and is highly selective for marginal zone lymphoma VL51 cell lines.
价 格:¥电议型 号:T63849产 地:中国大陆
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T63836Tubulin polymerization-IN-7;化合物 Tubulin polymerization-IN-7Tubulin polymerization-IN-7
Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.
价 格:¥电议型 号:T63836产 地:中国大陆
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T63725Tubulin polymerization-IN-35;化合物 Tubulin polymerization-IN-35Tubulin polymerization-IN-35
Tubulin polymerization-IN-35 is [1,2] an inhibitor of oxazolylisoindole microtubulin polymerization that acts highly selectively on the marginal zone lymphoma VL51 cell line.
价 格:¥电议型 号:T63725产 地:中国大陆
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T63611Tubulin polymerization-IN-32;化合物 Tubulin polymerization-IN-32Tubulin polymerization-IN-32
Tubulin polymerization-IN-32 is a tubulin polymerization inhibitor that inhibits the proliferation of cancer cells and can be used to study cancers such as lymphoma.
价 格:¥电议型 号:T63611产 地:中国大陆
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T63580Tubulin polymerization-IN-21;化合物 Tubulin polymerization-IN-21Tubulin polymerization-IN-21
Tubulin polymerization-IN-21 is an inhibitor of microtubulin polymerization that disrupts cell integrity and affects glucose metabolism, and has anticancer effects.
价 格:¥电议型 号:T63580产 地:中国大陆
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T63120Tubulin inhibitor 23;化合物 Tubulin inhibitor 23Tubulin inhibitor 23
Tubulin inhibitor 23 is a potent Tubulin inhibitor (IC50: 4.8 μM). Tubulin inhibitor 23 exhibited antiangiogenic effects in a dose-dependent manner and could induce apoptosis. Tubulin inhibitor 23 has potential for leukemia research.
价 格:¥电议型 号:T63120产 地:中国大陆
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T63111Tubulin polymerization-IN-33;化合物 Tubulin polymerization-IN-33Tubulin polymerization-IN-33
Tubulin polymerization-IN-33 is an [1,2] inhibitor of oxazoloisoindole microtubulin polymerization and is a good anti-proliferative agent for NCI series cancer cells.
价 格:¥电议型 号:T63111产 地:中国大陆
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T62971Tubulin polymerization-IN-16;化合物 Tubulin polymerization-IN-16Tubulin polymerization-IN-16
Tubulin aggregation-IN-16 (compound 5g) is a potent inhibitor of tubulin aggregation. 16 effectively disrupts microtubule/tubulin dynamics and induces cell cycle arrest at G2/M phase in SGC-7901 cells.
价 格:¥电议型 号:T62971产 地:中国大陆
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T62922Tubulin inhibitor 25;化合物 Tubulin inhibitor 25Tubulin inhibitor 25
Tubulin inhibitor 25 is a potent inhibitor of tubulin (IC50: 0.98 μM) and significantly inhibits HT29 cells. tubulin inhibitor 25 inhibits cell migration and microtubule formation and contributes to anti-angiogenesis.
价 格:¥电议型 号:T62922产 地:中国大陆
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T62693Tubulin polymerization-IN-29;化合物 Tubulin polymerization-IN-29Tubulin polymerization-IN-29
Tubulin polymerization-IN-29 is a potent inhibitor of microtubule protein polymerization and shows potent anti-proliferative effects.Tubulin polymerization-IN-29 induces cell cycle arrest in HeLa cells at G2/M phase.
价 格:¥电议型 号:T62693产 地:中国大陆