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T6287TariquidarTariquidar,XR9576,
Tariquidar(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.
价 格：￥电议型 号：T6287产 地：美洲
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T6337RepSoxRepSox,SJN 2511,E-616452
RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.
价 格：￥电议型 号：T6337产 地：美洲
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T83908DXR Inhibitor 11a (free acid)；化合物 DXR Inhibitor 11a (free acid)1-Deoxy-D-Xylulose-5-phosphate Reduct
DXR inhibitor 11a, with an IC50 of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrating an IC50 of 0.37 ?M.
价 格：￥电议型 号：T83908产 地：中国大陆
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T83885DXR Inhibitor 11a sodium；化合物 DXR Inhibitor 11a sodium1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
DXR inhibitor 11a, with an IC50 value of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum´s growth in isolated human erythrocytes, with an IC50 of 0.37 ?M.
价 格：￥电议型 号：T83885产 地：中国大陆
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T83128Aminooxy CatB-LXR；化合物 Aminooxy CatB-LXRAminooxy CatB-LXR
Compound 10, Aminooxy CatB-LXR, constitutes an agent-linker conjugate for antibody-drug conjugates (ADC) [1].
价 格：￥电议型 号：T83128产 地：中国大陆
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T78781TrxR1-IN-1；化合物 TrxR1-IN-1TrxR1-IN-1
Compound 5j, also known as TrxR1-IN-1, is a TrxR1 inhibitor with an IC50 of 8.8 μM. It exhibits anticancer activity, demonstrating IC50 values of 1.5 μM in MCF-7, 1.7 μM in HeLa, 2.4 μM in BGC-823, 2.8 μM in SW-480, and 2.1 μM in A549 cells. Additionally, TrxR1-IN-1 possesses antioxidant activity, effectively scavenging the DPPH radical [1].
价 格：￥电议型 号：T78781产 地：中国大陆
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T7768RGX-104；化合物RGX-104 free AcidRGX 104|||inhibit|||RGX-104 free Acid|||LXR|||RGX-104 free Acid|||RGX-10
RGX-104 (RGX-104 free Acid) free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)
价 格：￥电议型 号：T7768产 地：中国大陆
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T76213HXR9 hydrochloride；化合物 HXR9 hydrochlorideHXR9 hydrochloride
HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells.
价 格：￥电议型 号：T76213产 地：中国大陆
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T75160FXR agonist 5；化合物 FXR agonist 5FXR agonist 5
FXR agonist 5 (compound 1), an FXR agonist, is utilized in research targeting diseases or disorders associated with metabolic inflammation [1].
价 格：￥电议型 号：T75160产 地：中国大陆
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T74996FXR agonist 3；化合物 FXR agonist 3FXR agonist 3
FXR agonist 3, an anti-NASH (Non-Alcoholic Steatohepatitis) agent, functions by activating FXR. It demonstrates anti-fibrogenic activity by inhibiting the expression of COL1A1, TGF-β1, α-SMA, and TIMP1. Additionally, it significantly mitigates liver steatosis and inflammation and enhances the liver fibrosis level [1].
价 格：￥电议型 号：T74996产 地：中国大陆
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T74754FXR antagonist 2；化合物 FXR antagonist 2FXR antagonist 2
Compound A-26, also known as FXR antagonist 2, is a diarylamide derivative that functions as a moderate FXR antagonist. It is utilized in researching hyperlipidemia and type 2 diabetes [1].
价 格：￥电议型 号：T74754产 地：中国大陆
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T73254TrxR-IN-4；化合物 TrxR-IN-4TrxR-IN-4
Compound 1b (TrxR-IN-4) is a potent TrxR inhibitor that activates endoplasmic reticulum stress (ERS) to induce apoptosis in HepG2 cells and mitigates CCl4-induced liver damage in vivo through TrxR expression down-regulation and reduced inflammation [1].
价 格：￥电议型 号：T73254产 地：中国大陆
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T72889FXR agonist 4；化合物 FXR agonist 4FXR agonist 4
FXR agonist 4 with an EC 50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD) [1] .
价 格：￥电议型 号：T72889产 地：中国大陆
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T72186Tariquidar dihydrochloride；化合物 Tariquidar dihydrochlorideXR9576 dihydrochloride；XR9576 dihydrochlori
Tariquidar dihydrochloride, also known as XR9576 dihydrochloride, is a potent, specific P-glycoprotein (P-gp) inhibitor exhibiting high affinity (Kd = 5.1 nM).
价 格：￥电议型 号：T72186产 地：中国大陆
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T71189RX 809055AX；化合物 RX 809055AXRX 809055AX
RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.
价 格：￥电议型 号：T71189产 地：中国大陆
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T70417XR 1853；化合物 XR 1853XR 1853
XR 1853 is a low molecular weight modulator of human plasminogen activator inhibitor-1 activity.
价 格：￥电议型 号：T70417产 地：中国大陆
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T69618XR3054；化合物 XR3054XR3054
XR3054 is a novel inhibitor of farnesyl protein transferase (FPTase). XR3054 inhibited the proliferation of the prostatic cancer cell lines LnCAP and PC3 and the colon carcinoma SW480 and HT1080 (IC50 values of 12.4, 12.2, 21.4 and 8.8 microM, respectively) but was relatively inactive when tested against a panel of breast carcinoma cell lines. The activity did not relate to the presence of mutant or wild-type ras in the cell lines tested. In conclusion XR3054 inhibits ras farnesylation, MAP kina
价 格：￥电议型 号：T69618产 地：中国大陆
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T69273Mexrenoate potassium；化合物 Mexrenoate potassiumMexrenoate potassium
Mexrenoate potassium is a steroidal aldosterone antagonist and antihypertensive.
价 格：￥电议型 号：T69273产 地：中国大陆
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T68737XR9051；化合物 XR9051XR9051
XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 +/- 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein.
价 格：￥电议型 号：T68737产 地：中国大陆
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T6467Cardioxane；右雷佐生盐酸盐ADR-529 Hydrochloride|||ICRF-187 hydrochloride|||ADR-529|||Dexrazoxane HCl|||Cardi
Cardioxane (ADR-529) is a cardio-protective drug.
价 格：￥电议型 号：T6467产 地：中国大陆
