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T21561WAY-100635;化合物 T21561WAY-100635
WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 of 0.91 nM and Ki of 0.39 nM. It exhibits pIC50 values of 8.9 and 6.6 for 5-HT1A and α1-adrenergic receptors, respectively. Moreover, WAY-100635 acts as a potent agonist of the dopamine D4 receptor [1] [2] [3].
价 格:¥电议型 号:T21561产 地:中国大陆
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T21448Abafungin;阿巴芬净Bay w 6341|||UNII-11DI31LWXF;阿巴芬净|||Bay w 6341|||UNII-11DI31LWXF
Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum.
价 格:¥电议型 号:T21448产 地:中国大陆
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T21410Triptorelin acetate(57773-63-4 free base);醋酸曲普瑞林Wy 42422|||Triptorelin Acetate|||CL 118532|||AY 2565
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stimulation of the pituitary. Triptorelin acetate(57773-63-4 free base) may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, precocious puberty, estrogen-dependent conditions, and assisted reproduction.
价 格:¥电议型 号:T21410产 地:中国大陆
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T21395Finerenone;化合物FinerenoneBAY948862|||BAY-948862|||BAY94-8862|||BAY 94-8862|||BAY-94-8862|||BAY 948862
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
价 格:¥电议型 号:T21395产 地:中国大陆
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T21351Maytansine;美坦新NSC-153858|||NSC153858|||Maitansina|||NSC 153858|||Maitansine;NSC-153858|||NSC153858||
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
价 格:¥电议型 号:T21351产 地:中国大陆
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T21016Cyproterone;化合物 T21016BAY 94-8367|||Ciproterone|||Androcur|||SH 80881;BAY 94-8367|||Ciproterone|||An
Cyproterone, an anti-androgen, is used in combination with estrogen for the therapy of hirsutism and severe acne in females and as a palliative in prostatic carcinoma.
价 格:¥电议型 号:T21016产 地:中国大陆
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T209452,4-D;2,4-二氯苯氧乙酸Hedonal|||Macondray|||2,4-D acid|||Chloroxone;Hedonal|||Macondray|||2,4-D acid|||Chl
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the actin cytoskeleton for the control of root elongation and cell production.
价 格:¥电议型 号:T20945产 地:中国大陆
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T20770BAY32-59158-羟基喹啉-2-羧酸BAY-32-5915|||BAY 32-5915|||8-羟基喹啉-2-羧酸|||BAY 32 5915
BAY32-5915 is a selective inhibitor of IKKalpha.
价 格:¥电议型 号:T20770产 地:中国大陆
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T20600Kaolin;高岭土Clay 347|||Hydrated aluminum silicate|||Bolus alba|||HSDB 630|||Altowhite|||China clay;Cla
Kaolin (Bolus alba) is a clay dominated by minerals of the kaolinite family. Kaolin increased the sensitivity of this method for monitoring hemophilia therapy.
价 格:¥电议型 号:T20600产 地:中国大陆
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T20260Risocaine化合物 T20260Propylcain|||Raythesin|||Risocaina
Risocaine is an agent of local anesthetic.
价 格:¥电议型 号:T20260产 地:中国大陆
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T20231Cellufluor;化合物 T20231Phorwite AR|||Paper White BP|||Kayaphor FB|||Tinopal 5BMS;Phorwite AR|||Paper W
Cellufluor is a fluorochrome. It has an affinity for chitin and cellulose.
价 格:¥电议型 号:T20231产 地:中国大陆
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T1992Mertansine;化合物MertansineDM1|||Maytansinoid DM1;DM1|||Maytansinoid DM1
Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2´-deacetyl-N2´-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an antibody-drug conjugate or ADC. Experimental ADCs with the SPP-DM1 design include lorvotuzumab mertansine.
价 格:¥电议型 号:T1992产 地:中国大陆
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T1984LCinaciguat hydrochloride;化合物 T1984LBAY582667|||BAY58-2667|||BAY 582667|||BAY-582667|||BAY 58-2667|||
Cinaciguat( BAY582667, BAY58-2667) is a soluble guanosine cyclase activator that can prevent cardiac dysfunction in rat models of type 1 diabetes.
价 格:¥电议型 号:T1984L产 地:中国大陆
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T1984Cinaciguat;化合物CinaciguatBAY 58-2667;BAY 58-2667
Cinaciguat (BAY 58-2667) (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
价 格:¥电议型 号:T1984产 地:中国大陆
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T1983CAY10603;化合物CAY10603HDAC6 Inhibitor|||BML-281;HDAC6 Inhibitor|||BML-281
CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.
价 格:¥电议型 号:T1983产 地:中国大陆
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T1971WAY-262611;化合物WAY-262611WAY-262611
WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.
价 格:¥电议型 号:T1971产 地:中国大陆
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T1934Bay 11-7085;化合物Bay 11-7085BAY 11-7083;BAY 11-7083
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
价 格:¥电议型 号:T1934产 地:中国大陆
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T19202BAY-678 racemate;化合物 T19202BAY-678 racemate
BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, selective and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).
价 格:¥电议型 号:T19202产 地:中国大陆
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T1902BAY 11-7082化合物BAY 11-7082BAY 11-7821
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM). BAY 11-7082 is also an inhibitor of the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
价 格:¥电议型 号:T1902产 地:中国大陆
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T1792Regorafenib;瑞戈非尼BAY 73-4506|||Fluoro-Sorafenib;BAY 73-4506|||瑞戈非尼|||Fluoro-Sorafenib|||瑞格非尼
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.
价 格:¥电议型 号:T1792产 地:中国大陆