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T1529Miglitol米格列醇BAY1099|||米格列醇|||BAY-m1099
Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
价 格：￥电议型 号：T1529产 地：中国大陆
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T15215Emiglitate；化合物 T15215BAY o 1248；BAY o 1248
Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor.
价 格：￥电议型 号：T15215产 地：中国大陆
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T14998Copanlisib dihydrochloride；库潘尼西盐酸BAY 80-6946 dihydrochloride；库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格：￥电议型 号：T14998产 地：中国大陆
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T14974Citenamide；西替酰胺Cytenamide|||AY-15613；Cytenamide|||AY-15613
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.
价 格：￥电议型 号：T14974产 地：中国大陆
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T14878CAY10566；化合物CAY10566CAY10566
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..
价 格：￥电议型 号：T14878产 地：中国大陆
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T14511BAY1082439化合物BAY1082439N-[8-[[(2R)-2-羟基-3-(吗啉-4-基)丙基]氧基]-7-甲氧基-2,3-二氢咪唑并[1,2-C]喹唑啉-5-基]-2-甲基吡啶-3-甲酰胺
BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms of PIK3CA.
价 格：￥电议型 号：T14511产 地：中国大陆
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T14510BAY-850；化合物BAY-850BAY-850
BAY-850 is a selective and potent inhibitor of adenosine triphosphatase family protein 2 (ATAD2) (IC50: 166 nM) that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.
价 格：￥电议型 号：T14510产 地：中国大陆
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T14509BAY-707；化合物 T14509BAY-707
BAY-707, a highly potent and selective substrate-competitive inhibitor of MTH1 (NUDT1) with an IC50 of 2.3 nM, is well-tolerated in mice and exhibits a favorable pharmacokinetic (PK) profile compared to other MTH1 compounds. However, it demonstrates a clear lack of anticancer efficacy both in vitro and in vivo[1].
价 格：￥电议型 号：T14509产 地：中国大陆
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T14508Bay 65-1942 hydrochloride；化合物 T14508Bay 65-1942 hydrochloride
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
价 格：￥电议型 号：T14508产 地：中国大陆
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T14507Bay 60-7550；化合物 Bay 60-7550BAY 607550；BAY 607550
Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and memory disorders.
价 格：￥电议型 号：T14507产 地：中国大陆
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T14506BAY 60-6583；化合物BAY 60-6583BAY 60-6583
BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively.
价 格：￥电议型 号：T14506产 地：中国大陆
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T14505BAY-524；化合物BAY524BAY-524
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).
价 格：￥电议型 号：T14505产 地：中国大陆
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T14504BAY 38-7271；化合物 T14504BAY 38-7271
BAY 38-7271 has strong neuroprotective properties.[1] BAY 38-7271 is selective and highly potent and cannabinoid CB1/CB2 receptor agonist. With Kis of 1.85 nM and 5.96 nM for recombinant human CB1 receptor and CB2 receptor, respectively.
价 格：￥电议型 号：T14504产 地：中国大陆
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T14503BAY-320；化合物 T14503BAY-320
BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.
价 格：￥电议型 号：T14503产 地：中国大陆
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T14502BAY-299；化合物BAY-299BAY299|||BAY 299；BAY299|||BAY 299
BAY-299 is an effecitve inhibitor of the bromodomain and PHD finger family member BRPF2 and the TATA box binding protein-associated factors TAF1 and TAF1L with IC50s of 67 nM, 8 nM, and 106 nM, respectively.
价 格：￥电议型 号：T14502产 地：中国大陆
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T14501BAY-2402234；化合物BAY-2402234BAY-2402234
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.
价 格：￥电议型 号：T14501产 地：中国大陆
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T14500BAY-1316957；化合物 T14500BAY-1316957
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
价 格：￥电议型 号：T14500产 地：中国大陆
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T14362LAY 9944 dihydrochloride；化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格：￥电议型 号：T14362L产 地：中国大陆
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T14362AY 9944；化合物AY 9944AY 9944
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
价 格：￥电议型 号：T14362产 地：中国大陆
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T14324Artemisone；青蒿酮BAY 44-9585|||Artemifone；BAY 44-9585|||Artemifone|||青蒿酮
Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
价 格：￥电议型 号：T14324产 地：中国大陆
