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T7700LersivirineHIV,non-nucleoside reverse transcription,Reverse Transcriptase,HIV virus,UK 453061,Inhibi
Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
价 格:¥电议型 号:T7700产 地:中国大陆
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TN1770Isomogroside VInhibitor,inhibit,Isomogroside V
Isomogroside V is a sweetener extracted from Siraitia grosvenorii that is approximately 500 times sweeter than 0.5% (w/v) sucrose.
价 格:¥电议型 号:TN1770产 地:中国大陆
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T9980AVJ16AVJ16
AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.
价 格:¥电议型 号:T9980产 地:中国大陆
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TP1174Endothelin-2 (49-69), humanpeptide,21-amino,inhibit,Human endothelin 2,vasoactive,acid,ET-RB,Endothe
Endothelin-2, human is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
价 格:¥电议型 号:TP1174产 地:中国大陆
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T6440CGP 57380CGP-57380,CGP 57380,Mitogen activated protein kinase interacting kinase,Inhibitor,MAPK inte
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
价 格:¥电议型 号:T6440产 地:中国大陆
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TN2423SafranalSafranal,disease,inhibit,anti-inflammatory,Saffron,Inhibitor,Parkinson’s,neuroprotective,ora
Safranal is the special volatile aroma compound of saffron.Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinson’s disease research.
价 格:¥电议型 号:TN2423产 地:中国大陆
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T13173TMPAinhibit,hepatic LO2,AMPKα,TMPA,type II diabetes,AMPK,T cells,Inhibitor,AMP-activated protein kin
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
价 格:¥电议型 号:T13173产 地:中国大陆
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T18870Vc-MMADVc MMAD,VcMMAD
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a drug-linker conjugate for ADC.
价 格:¥电议型 号:T18870产 地:中国大陆
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T8469LQZ-7ILQZ7I,inhibit,Survivin,LQZ 7I,Inhibitor,tumor,LQZ-7I,dimerization
LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors
价 格:¥电议型 号:T8469产 地:中国大陆
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T9066MerafloxacinMerafloxacin,frameshifting,SARS-CoV,bacteria,antibacterial,fluoroquinolone,Inhibitor,CI9
Merafloxacin is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.
价 格:¥电议型 号:T9066产 地:中国大陆
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T8374LJ570inhibit,Peroxisome proliferator-activated receptors,LJ-570,LJ 570,LJ570,Inhibitor,PPAR
LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)
价 格:¥电议型 号:T8374产 地:中国大陆
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T9088TopovaleTopovale
Topovale is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibited low nM cytotoxicity against a panel of cancer cells. Topovale cytotoxicity as well as Topovale-induced apoptosis was reduced > 100-fold in CPT-resistant topoisomerase I (TOP1)-deficient P388/CPT45 cells as compared with P388 cells.
价 格:¥电议型 号:T9088产 地:中国大陆
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T7581voxelotorGBT440,voxelotor,polymerization,haemoglobin,sickle,GBT-440,SCD,inhibit,cell,disease,Inhibit
voxelotor is an inhibitor of sickle hemoglobin (HbS)
价 格:¥电议型 号:T7581产 地:中国大陆
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T60016VV116VV116
VV116 is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection.
价 格:¥电议型 号:T60016产 地:中国大陆
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T8840PF-543 hydrochlorideNrf-2,PF543 hydrochloride,anti-cancer,sphingosine-competitive,S1P,Sphingosine Ki
PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
价 格:¥电议型 号:T8840产 地:中国大陆
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T6S2227SpinosinInhibitor,neuroprotective,Spinosin,inhibit,Aβ1-42
1. Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher
价 格:¥电议型 号:T6S2227产 地:中国大陆
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TQ0200ParicalcitolVitamin D receptor,Paricalcitol,Vitamin D,Inhibitor,VD/VDR,inhibit
Paricalcitol is a vitamin D receptor agonist. It is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
价 格:¥电议型 号:TQ0200产 地:中国大陆
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T6909NSC348884lymphoma,cancer,inhibit,SKOV3,MOSEC/Luc cell,NSC-348884,NSC 348884,LNCaP,doxorubicin,NSC348
NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.
价 格:¥电议型 号:T6909产 地:中国大陆
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T9377ASK1-IN-2colitis,ulcerative,signal-regulating,ASK1 IN 2,ASK1IN2,inhibit,MAP kinase kinase kinase, ME
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
价 格:¥电议型 号:T9377产 地:中国大陆
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T9956VK-28VK28,VK 28
VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.
价 格:¥电议型 号:T9956产 地:中国大陆