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T69607Dersimelagon phosphate;化合物 Dersimelagon phosphateDersimelagon phosphate
Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP/XLP patients.
价 格:¥电议型 号:T69607产 地:中国大陆
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T6944Thiophanate-Methyl;甲基硫菌灵Thiophanate-Methyl
Thiophanate-Methyl (TM), a methyl benzimidazole carbamate (MBC) fungicide,
价 格:¥电议型 号:T6944产 地:中国大陆
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T6940PHA-767491 hydrochloride;化合物PHA767491 HClCAY10572|||PHA-767491|||PHA767491 HCl|||CAY-10572 hydrochlo
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
价 格:¥电议型 号:T6940产 地:中国大陆
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T69296PHA-680626;化合物 PHA-680626PHA-680626
PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases. PHA-680626 inhibits Plk1 (IC50 = 0.53 μM), Plk2 (IC50 = 0.07 μM) and Plk3 (IC50 = 1.61 μM).
价 格:¥电议型 号:T69296产 地:中国大陆
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T69264Aristeromycin diphosphate;化合物 Aristeromycin diphosphateAristeromycin diphosphate
Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibition of prostate cancer.
价 格:¥电议型 号:T69264产 地:中国大陆
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T69060Dextrallorphan;化合物 DextrallorphanDextrallorphan
Dextrallorphan (DXA) is an chemical of the morphinan class that is used in scientific research. It acts as a σ1 receptor agonist and NMDA receptor antagonist. It has no significant affinity for the σ2, μ-opioid, or δ-opioid receptor, or for the serotonin or norepinephrine transporter. As an NMDA receptor antagonist, in vivo, it is approximately twice as potent as dextromethorphan, and five-fold less potent than dextrorphan. Dextrallorphan was found to have a half maximal inhibitory concentration
价 格:¥电议型 号:T69060产 地:中国大陆
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T68963alpha-Clopenthixol dihydrochloride;化合物 alpha-Clopenthixol dihydrochloridealpha-Clopenthixol dihydroc
alpha-Clopenthixol dihydrochloride is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
价 格:¥电议型 号:T68963产 地:中国大陆
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T68867Trimethaphan camsylate;化合物 Trimethaphan camsylateTrimethaphan camsylate
Trimethaphan camsylate is a nicotinic antagonist that has been used as a ganglionic blocker in hypertension.
价 格:¥电议型 号:T68867产 地:中国大陆
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T68811Trimetaphan camsilate;化合物 Trimetaphan camsilateTrimetaphan camsilate
Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system. It acts as a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptor, is short-acting, and is given intravenously.
价 格:¥电议型 号:T68811产 地:中国大陆
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T68656Brivudine monophosphate;化合物 Brivudine monophosphateBrivudine monophosphate
Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator
价 格:¥电议型 号:T68656产 地:中国大陆
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T68601Azidothiorphan;化合物 AzidothiorphanAzidothiorphan
Azidothiorphan is a photoaffinity ligand for the active site of the neutral endopeptidase 24.11. After ultraviolet irradiation the inhibitor binds irreversibly to the enzyme, and photolabeling occurs at the active site. The competitive inhibitor thiorphan protects the endopeptidase from inactivation.
价 格:¥电议型 号:T68601产 地:中国大陆
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T68551Cabergoline diphosphate;化合物 Cabergoline diphosphateCabergoline diphosphate
Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
价 格:¥电议型 号:T68551产 地:中国大陆
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T68495Ganciclovir triphosphate;化合物 Ganciclovir triphosphateGanciclovir triphosphate
Ganciclovir triphosphate is a synthetic analog of 2´-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.
价 格:¥电议型 号:T68495产 地:中国大陆
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T6820D-α-Hydroxyglutaric acid disodium;(R)-2-羟基戊二酸二钠盐D-alpha-Hydroxyglutaric acid disodium salt|||Disodiu
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
价 格:¥电议型 号:T6820产 地:中国大陆
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T67906Bis(2-methoxy-5-((Z)-3,4,5-trimethoxystyryl)phenyl) hydrogen phosphate;化合物 T67906Bis(2-methoxy-5-((Z
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1´-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.
价 格:¥电议型 号:T67906产 地:中国大陆
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T67888LSamidorphan HCl;沙米多芬盐酸盐Samidorphan HCl(852626-89-2 free base);Samidorphan HCl(852626-89-2 free base)
Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors. Samidorphan HCl is a novel μ-opioid receptor antagonist, a partial agonist for k-opioid and delta-opioid receptors. Samidorphan HCl can be used to prevent and treat schizophrenia.
价 格:¥电议型 号:T67888L产 地:中国大陆
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T67888Iso-Samidorphan;沙米多芬异构体(9ξ,13ξ,14ξ)-17-(Cyclopropylmethyl)-4,14-dihydroxy-6-oxomorphinan-3-carboxami
Iso-Samidorphan is a biochemical reagent that can be used in biological experiments.
价 格:¥电议型 号:T67888产 地:中国大陆
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T67739BMY-14802;化合物BMY-14802alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol;alpha-(
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
价 格:¥电议型 号:T67739产 地:中国大陆
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T67689Sodium 4-nitrophenyl phosphate hexahydrate;化合物 Sodium 4-nitrophenyl phosphate hexahydrateSodium 4-ni
Sodium 4-nitrophenyl phosphate hexahydrate is a useful organic compound for research related to life sciences. The catalog number is T67689 and the CAS number is 333338-18-4.
价 格:¥电议型 号:T67689产 地:中国大陆
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T67238Acetonitrilebis[2-diphenylphosphino-6-t-butylpyridine]cyclopentadienylruthenium(II) hexafluorophosph
Acetonitrilebis[2-diphenylphosphino-6-t-butylpyridine]cyclopentadienylruthenium(II) hexafluorophosphate is a useful organic compound for research related to life sciences and the catalog number is T67238.
价 格:¥电议型 号:T67238产 地:中国大陆