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T6272Fosbretabulin Disodium;福他布林Combretastatin A4 Phosphate|||CA 4DP|||CA 4P|||Combretastatin A4 disodium
Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 μM), and also disrupts tumor vasculature.
价 格:¥电议型 号:T6272产 地:中国大陆
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T62331Autophagy-IN-1;化合物 Autophagy-IN-1Autophagy-IN-1
Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in the HCT116 mouse xenograft tumour model with low toxicity.Autophagy-IN-1 can be used to study colorectal cancer.
价 格:¥电议型 号:T62331产 地:中国大陆
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T6206PHA-767491;化合物PHA767491CAY10572|||PHA767491|||PHA 767491;CAY10572|||PHA767491|||PHA 767491
PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
价 格:¥电议型 号:T6206产 地:中国大陆
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T61987PHA 568487;化合物 PHA 568487PHA 568487
PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor ( α-7 nAchR ). PHA-568487 shows rapid brain penetration. PHA 568487 reduces oxidative stress and neuroinflammation.
价 格:¥电议型 号:T61987产 地:中国大陆
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T61834trans-Cephalosporin;化合物 trans-Cephalosporintrans-Cephalosporin
Trans-substituted cephalosporin is an efficient inhibitor of NDM-1, demonstrating an IC50 value of 0.13 μM.
价 格:¥电议型 号:T61834产 地:中国大陆
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T61580Autophagy inducer 3;化合物 Autophagy inducer 3Autophagy inducer 3
Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal autophagy through the formation of distinct autophagic vacuoles, LC3 puncta formation, and upregulation of signature autophagy markers such as Beclin and Atg family proteins [1].
价 格:¥电议型 号:T61580产 地:中国大陆
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T6128PHA-665752;化合物PHA665752PHA 665752|||PHA665752;PHA 665752|||PHA665752
PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.
价 格:¥电议型 号:T6128产 地:中国大陆
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T6127Rucaparib Phosphate;瑞卡帕布磷酸盐AG-014699 phosphate|||PF-01367338|||AG-014699|||PF-01367338 phosphate;AG-
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:中国大陆
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T6112Doxercalciferol;度骨化醇TSA 840|||Hectorol|||1.alpha.-Hydroxyvitamin D2|||1α-hydroxyvitamin D2;TSA 840||
Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
价 格:¥电议型 号:T6112产 地:中国大陆
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T6081Milciclib;化合物MilciclibPHA-848125;PHA-848125
Milciclib (PHA-848125) (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2.
价 格:¥电议型 号:T6081产 地:中国大陆
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T60749Autophagy-IN-2;化合物 Autophagy-IN-2Autophagy-IN-2
Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for the research of triple-negative breast cancer [1].
价 格:¥电议型 号:T60749产 地:中国大陆
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T60709Acyclovir monophosphate;化合物 Acyclovir monophosphateAcyclovir monophosphate
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agen which also has antitumor activity. Acyclovir monophosphate blocks synthesis of DNA by inhibiting the viral DNA polymerase and terminates the chain elongation of the viral DNA [1] [2].
价 格:¥电议型 号:T60709产 地:中国大陆
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T60276Cyclocreatine phosphate;化合物 Cyclocreatine phosphateCyclocreatine phosphate
Cyclocreatine phosphate is an anti-tumor agent. Cyclocreatine phosphate(CCrP) is the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. Cyclocreatine and its water-soluble derivative, cyclocreatine phosphate (CCrP), are potent cardioprotective drugs. Cyclocreatine phosphate can be used for the research of cancer[1].
价 格:¥电议型 号:T60276产 地:中国大陆
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T60254Calcium glycerophosphate;甘油磷酸钙Calcium glycerophosphate
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].
价 格:¥电议型 号:T60254产 地:中国大陆
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T5S1981alpha-Cyperone;α-香附酮(+)-α-Cyperone|||α-Cyperone;(+)-α-Cyperone|||α-香附酮|||α-Cyperone
1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of
价 格:¥电议型 号:T5S1981产 地:中国大陆
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T5S1679Acetylshengmanol Arabinoside;乙酰升麻醇-3-O-α-L-阿拉伯糖苷Acetylcimigenol 3-O-alpha-L-arabinopyran;乙酰升麻醇-3-O-α
Acetylcimigenol 3-O-alpha-L-arabinopyranoside is an extract derived from Cimicifuga.
价 格:¥电议型 号:T5S1679产 地:中国大陆
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T5S0814Berberine hydrogen sulphate;硫酸小檗碱Berberine Bisulfate|||Umbellatine Sulfate;Berberine Bisulfate|||硫酸氢
Berberine hydrogen sulphate (Umbellatine Sulfate) , an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
价 格:¥电议型 号:T5S0814产 地:中国大陆
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T5S0273Hypaphorine;刺桐碱Lenticin|||Glyyunnanenine|||Tryptophan Betaine;Lenticin|||Glyyunnanenine|||Tryptophan
1. Hypaphorine (Lenticin) is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.
价 格:¥电议型 号:T5S0273产 地:中国大陆
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T59802-Ketoglutaric acidα-酮戊二酸α-酮戊二酸|||alpha-酮戊二酸
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
价 格:¥电议型 号:T5980产 地:中国大陆
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T5954Methyldopa hydrate;L-甲基多巴Alpha-Methyldopa Sesquihydrate|||L-(-)-α-Methyldopa hydrate|||MK-351 hydrat
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
价 格:¥电议型 号:T5954产 地:中国大陆