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T18317MCC-Modified Daunorubicinol;化合物 T18317MCC-Modified Daunorubicinol
Daunorubicinol, a potent antitumor drug-linker conjugate for antibody-drug conjugate (ADC) applications, utilizes Aur0101 (DNA Topoisomerase II inhibitor) connected through the ADC linker[1].
价 格:¥电议型 号:T18317产 地:中国大陆
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T18266Mal-PEG-Succinimidyl Valerate (MW 20000);化合物 T18266Mal-PEG-Succinimidyl Valerate (MW 20000)
Mal-PEG-Succinimidyl Valerate (MW 20000) is a polyethylene glycol (PEG)-based linker with a molecular weight of 20000. It serves as an essential component in the synthesis of PROTACs, which are proteolysis targeting chimeras.
价 格:¥电议型 号:T18266产 地:中国大陆
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T18107m-PEG-Succinimidyl Succinate (MW 5000);化合物 T18107m-PEG-Succinimidyl Succinate (MW 5000)
m-PEG-Succinimidyl Succinate (MW 5000) is a polyethylene glycol (PEG)-based linker featuring succinimidyl succinate functionality, primarily applied in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18107产 地:中国大陆
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T17833DM4-SMCC;化合物 T17833DM4-SMCC
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].
价 格:¥电议型 号:T17833产 地:中国大陆
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T17727CCK2R Ligand-Linker Conjugates 1;化合物 T17727CCK2R Ligand-Linker Conjugates 1
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
价 格:¥电议型 号:T17727产 地:中国大陆
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T17687ACC2;化合物7ACC27ACC2
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
价 格:¥电议型 号:T1768产 地:中国大陆
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T17225Vercirnon;维塞诺CCX282-B|||GSK-1605786|||Traficet-EN;CCX282-B|||维塞诺|||GSK-1605786|||Traficet-EN
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
价 格:¥电议型 号:T17225产 地:中国大陆
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T16899SMCC-DM1;化合物SMCC-DM1DM1-SMCC;DM1-SMCC
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
价 格:¥电议型 号:T16899产 地:中国大陆
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T16726Rebeccamycin;化合物 T16726Rebeccamycin
Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.
价 格:¥电议型 号:T16726产 地:中国大陆
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T16562Ponceau 4R胭脂红Acid Red 18|||New Coccine
Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usually synthesized from aromatic hydrocarbons.
价 格:¥电议型 号:T16562产 地:中国大陆
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T1642Lenalidomide来那度胺来那度胺|||CC-5013
Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.
价 格:¥电议型 号:T1642产 地:中国大陆
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T16251N-Succinimidyl-S-acetylthioacetate;N-丁二酸,S-乙酰基巯基乙二醇酯SATA;SATA|||N-丁二酸,S-乙酰基巯基乙二醇酯
N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as Sulfo-SMCC, Sulfo-MBS, etc.
价 格:¥电议型 号:T16251产 地:中国大陆
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T16250N-Succinimidyl 3-(Bromoacetamido)propionate;化合物 T162503-(2-Bromoacetamido)propanoic acid NHS ester;3
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker employed in the synthesis of PROTACs and antibody-drug conjugates (ADCs) [1, 2]. It acts as a cleavable ADC linker, facilitating the conjugation of drugs to antibodies for targeted delivery [2].
价 格:¥电议型 号:T16250产 地:中国大陆
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T16225N-Hydroxysulfosuccinimide sodium;N-羟基琥珀酰亚胺磺酸钠盐N-Hydroxysulfosuccinimide sodium
N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
价 格:¥电议型 号:T16225产 地:中国大陆
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T16091MK-0812 Succinate;化合物MK-0812 SuccinateMK-0812 Succinate
MK-0812 Succinate is an effective and selective CCR2 antagonist.
价 格:¥电议型 号:T16091产 地:中国大陆
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T1601Lomustine;洛莫司汀CCNU|||NSC 79037;CCNU|||NSC 79037|||洛莫司汀
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
价 格:¥电议型 号:T1601产 地:中国大陆
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T15937m-PEG8-succinimidyl carbonate;化合物 T15937m-PEG8-succinimidyl carbonate
m-PEG8-succinimidyl carbonate is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T15937产 地:中国大陆
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T15901m-PEG5-succinimidyl carbonate;化合物 T15901m-PEG5-succinimidyl carbonate
m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T15901产 地:中国大陆
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T15865m-PEG3-succinimidyl carbonate;化合物 T15865m-PEG3-succinimidyl carbonate
m-PEG3-succinimidyl carbonate is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T15865产 地:中国大陆
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T1580Desvenlafaxine;去甲文拉法辛WY 45233 Succinate|||O-Desmethylvenlafaxine;去甲文拉法辛|||WY 45233 Succinate|||O-Des
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.
价 格:¥电议型 号:T1580产 地:中国大陆