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T15732Ribociclib succinate;瑞博西尼琥珀酸盐LEE011 succinate;LEE011 琥珀酸盐|||瑞博西尼琥珀酸盐|||LEE011 succinate
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
价 格:¥电议型 号:T15732产 地:中国大陆
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T15731Ribociclib succinate hydrate化合物 T15731LEE011 succinate hydrate
Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
价 格:¥电议型 号:T15731产 地:中国大陆
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T1561Clobetasol propionate;丙酸氯倍他索Dermovate|||Clobetasol 17-propionate|||CGP9555|||Temovate|||CCl 4725;Der
Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clo
价 格:¥电议型 号:T1561产 地:中国大陆
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T15499HOOCCH2O-PEG4-CH2COOH;化合物 T15499HOOCCH2O-PEG4-CH2COOH
HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.
价 格:¥电议型 号:T15499产 地:中国大陆
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T15161Doxorubicin-SMCC;化合物 T15161Doxorubicin-SMCC
Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15161产 地:中国大陆
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T14909CCX140;化合物CCX140CCX140-B;3-三氟甲基-4-氯-N-[2-[7H-吡咯并[2,3-D]嘧啶-4-羰基]-5-甲基-3-吡啶基]苯磺酰胺|||CCX140-B
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.
价 格:¥电议型 号:T14909产 地:中国大陆
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T14908CCT367766;化合物CCT367766CCT367766
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low conc
价 格:¥电议型 号:T14908产 地:中国大陆
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T14907CCT251545;化合物CCT251545CCT251545
CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).
价 格:¥电议型 号:T14907产 地:中国大陆
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T14906CCT251455;化合物 T14906CCT251455
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
价 格:¥电议型 号:T14906产 地:中国大陆
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T14905CCT251236;化合物 CCT251236CCT251236
CCT251236 is a cell-based phenotypic high-throughput screening (HTS) chemical probe developed to screen for inhibitors of the HSF1 stress pathway.CCT251236 exhibits antimyeloma activity and inhibits HSF1.
价 格:¥电议型 号:T14905产 地:中国大陆
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T14904CCT244747;化合物 T14904CCT244747
CCT244747 is a CHK1 inhibitor (IC50: 7.7 nM) and also abrogates G2 checkpoint (IC50: 29 nM).
价 格:¥电议型 号:T14904产 地:中国大陆
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T14903CCT129957;化合物CCT129957CCT129957
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
价 格:¥电议型 号:T14903产 地:中国大陆
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T14902CCT020312;化合物CCT020312CCT020312
CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A.
价 格:¥电议型 号:T14902产 地:中国大陆
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T14901CCT-251921;化合物CCT-251921CCT-251921
CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).
价 格:¥电议型 号:T14901产 地:中国大陆
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T14900CCR2-RA-[R]化合物CCR2-RA-[R](5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
价 格:¥电议型 号:T14900产 地:中国大陆
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T14899CCR1 antagonist 8;化合物 T14899CCR1 antagonist 8
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay).
价 格:¥电议型 号:T14899产 地:中国大陆
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T14898CCG-63808;化合物CCG-63808CCG-63808
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.
价 格:¥电议型 号:T14898产 地:中国大陆
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T14897CCG-63802;化合物CCG-63802CCG-63802
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins. CCG-63802 inhibits the interaction between RGS4 and Galpha with an IC50 value of 1.4 μM.
价 格:¥电议型 号:T14897产 地:中国大陆
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T14896CC0651;化合物 T14896CC0651
CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently inhibits the ubiquitination of p27Kip1 (IC50: 1.72 μM).
价 格:¥电议型 号:T14896产 地:中国大陆
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T14895Tanzisertib;化合物TanzisertibCC-930;CC-930
Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.
价 格:¥电议型 号:T14895产 地:中国大陆