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T11824Lanraplenib succinate化合物 T11824GS-9876 succinate
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.
价 格：￥电议型 号：T11824产 地：中国大陆
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T1178Temozolomide；替莫唑胺NSC 362856|||TZM|||CCRG 81045|||TMZ；NSC 362856|||替莫唑胺|||TZM|||CCRG 81045|||TMZ
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
价 格：￥电议型 号：T1178产 地：中国大陆
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T11555Heptasaccharide Glc4Xyl3；化合物 T11555Heptasaccharide Glc4Xyl3
Heptasaccharide Glc4Xyl3 is a covalent inhibitor of endo-xyloglucanases. It used for the identification and analysis of diverse xyloglucan-active enzymes in nature.
价 格：￥电议型 号：T11555产 地：中国大陆
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T11326Frovatriptan succinate hydrate；夫罗曲坦琥珀酸盐水合物u00A0Frovelan|||Frova；Frovelan|||夫罗曲坦琥珀酸盐水合物u00A0|||Frova
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also be used as in mini-prophylaxis in menstrual migraine.?Frovatriptan succinate hydrate is a potent, high affinity, selective and orally active 5-HT1B, HT1D receptor agonist and a moderately potent 5-HT7 receptor agonist, with pKi values of 8.6, 8.4, and 6.7, respectively.
价 格：￥电议型 号：T11326产 地：中国大陆
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T11297FF-10101 succinate；化合物 T11297FF-10101 succinate
FF-10101 succinate is a potent FLT3 inhibitor.
价 格：￥电议型 号：T11297产 地：中国大陆
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T1115Doxylamine succinate；琥珀酸多西拉敏Decapryn；琥珀酸多西拉敏|||Decapryn
Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of the gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug a
价 格：￥电议型 号：T1115产 地：中国大陆
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T11142EACC；化合物EACCEACC
EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts autophagic flux.
价 格：￥电议型 号：T11142产 地：中国大陆
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T10789Chitosan oligosaccharide壳聚糖低聚乳酸酯COS|||壳聚糖低聚乳酸酯
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. It has the ability to activate AMPK and simultaneously inhibit inflammatory signaling pathways, including NF-κB and MAPK.
价 格：￥电议型 号：T10789产 地：中国大陆
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T10765Eragidomide；化合物 EragidomideCC-90009|||Cereblon modulator 1；CC-90009|||Cereblon modulator 1
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.
价 格：￥电议型 号：T10765产 地：中国大陆
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T10719CCT365623 hydrochloride；化合物 T10719CCT365623 hydrochloride
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
价 格：￥电议型 号：T10719产 地：中国大陆
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T10718LCCT241533 hydrochloride；化合物 T10718LCCT241533 hydrochloride
CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格：￥电议型 号：T10718L产 地：中国大陆
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T10718CCT241533；化合物 T10718CCT241533
CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格：￥电议型 号：T10718产 地：中国大陆
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T10716CCR7 Ligand 1；化合物 T10716CCR7-Cmp2105；CCR7-Cmp2105
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
价 格：￥电议型 号：T10716产 地：中国大陆
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T10715CCR6 inhibitor 1；化合物CCR6 inhibitor 1CCR6 inhibitor 1
CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.
价 格：￥电议型 号：T10715产 地：中国大陆
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T10714CCR5 antagonist 1；化合物 T10714CCR5 antagonist 1
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
价 格：￥电议型 号：T10714产 地：中国大陆
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T10713CCR4 antagonist 2；化合物 T10713CCR4 antagonist 2
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
价 格：￥电议型 号：T10713产 地：中国大陆
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T10712CCR2 antagonist 3；化合物CCR2 antagonist 3AZD-2927|||AZD2927；AZD-2927|||AZD2927
CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.
价 格：￥电议型 号：T10712产 地：中国大陆
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T10711CCR2 antagonist 1；化合物 T10711CCR2 antagonist 1
CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).
价 格：￥电议型 号：T10711产 地：中国大陆
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T10710CCR1 antagonist 9；化合物 T10710CCR1 antagonist 9
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
价 格：￥电议型 号：T10710产 地：中国大陆
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T10709CCR1 antagonist 7；化合物 T10709CCR1 antagonist 7
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
价 格：￥电议型 号：T10709产 地：中国大陆
