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T6006RomidepsinRomidepsin,FR 901228,NSC 630176
Romidepsin is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous and peripheral T cell lymphomas.
价 格：￥电议型 号：T6006产 地：美洲
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T6063LY411575LY411575
LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
价 格：￥电议型 号：T6063产 地：美洲
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T6110YM201636YM201636
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.
价 格：￥电议型 号：T6110产 地：美洲
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T6121TepotinibTepotinib,EMD-1214063,MSC2156119
Tepotinib is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
价 格：￥电议型 号：T6121产 地：美洲
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T6131PimasertibPimasertib,MSC1936369B,AS703026
Pimasertib is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格：￥电议型 号：T6131产 地：美洲
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T6137KRN-633KRN-633,KRN633,KRN 633
KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633 for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.
价 格：￥电议型 号：T6137产 地：美洲
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T6139A-674563A-674563,A674563,A 674563
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
价 格：￥电议型 号：T6139产 地：美洲
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T6191TasisulamTasisulam,LY573636,
Tasisulam is an apoptosis inducer and an antitumor agent via the intrinsic pathway.
价 格：￥电议型 号：T6191产 地：美洲
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T6215Abiraterone AcetateAbiraterone Acetate,CB7630,Zytiga
Abiraterone acetate is an androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.
价 格：￥电议型 号：T6215产 地：美洲
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T6241Quetiapine FumarateQuetiapine Fumarate,ICI-204636,
Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
价 格：￥电议型 号：T6241产 地：美洲
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T6249AvagacestatAvagacestat,BMS-708163,
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
价 格：￥电议型 号：T6249产 地：美洲
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T6300DegrasynDegrasyn,WP1130,
Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
价 格：￥电议型 号：T6300产 地：美洲
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T6301TosedostatTosedostat,CHR-2797,
CHR-2797 is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. CHR-2797 is converted intracellularly into a poorly membrane-permeable active metabolite (CHR-79888) which inhibits the M1 family of a
价 格：￥电议型 号：T6301产 地：美洲
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T6302LonafarnibLonafarnib,Sch66336,Sarasar
Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
价 格：￥电议型 号：T6302产 地：美洲
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T6305SNX-2112SNX-2112,SNX2112,SNX 2112
SNX-2112 is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格：￥电议型 号：T6305产 地：美洲
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T6307LubiprostoneLubiprostone,SPI-0211,RU-0211
Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
价 格：￥电议型 号：T6307产 地：美洲
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T6308StatticStattic,STAT3 Inhibitor V,
Stattic is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and nuclear translocation (IC50: 5.1 μM).
价 格：￥电议型 号：T6308产 地：美洲
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T6309AZ 960AZ 960
AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
价 格：￥电议型 号：T6309产 地：美洲
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T6310GW3965 HClGW3965 HCl,GW3965 hydrochloride,
GW3965 HCl is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).
价 格：￥电议型 号：T6310产 地：美洲
