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产品数:86101
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T6311BafetinibBafetinib,NS-187,INNO-406
Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
价 格:¥电议型 号:T6311产 地:美洲
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T6313Go 6983Go 6983,Goe 6983,G? 6983
Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.
价 格:¥电议型 号:T6313产 地:美洲
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T6316CalcitriolCalcitriol,1,25-Dihydroxyvitamin D3,RO215535
Calcitriol is the physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calci
价 格:¥电议型 号:T6316产 地:美洲
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T6319OSI-027OSI-027,OSI027,OSI 027
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1.
价 格:¥电议型 号:T6319产 地:美洲
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T6320GDC-0879GDC-0879,GDC0879,GDC 0879
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.
价 格:¥电议型 号:T6320产 地:美洲
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T6321TofacitinibTofacitinib,CP-690550,Tasocitinib
Tofacitinib is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis.
价 格:¥电议型 号:T6321产 地:美洲
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T6322CopanlisibCopanlisib,BAY 80-6946,
Copanlisib is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell
价 格:¥电议型 号:T6322产 地:美洲
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T6323Oligomycin AOligomycin A,MCH 32,
Oligomycin A is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.
价 格:¥电议型 号:T6323产 地:美洲
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T6324BIX02188BIX02188
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
价 格:¥电议型 号:T6324产 地:美洲
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T6325PCI-34051PCI-34051,PCI34051,PCI 34051
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
价 格:¥电议型 号:T6325产 地:美洲
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T6326BMS-345541BMS-345541,BMS345541,BMS 345541
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
价 格:¥电议型 号:T6326产 地:美洲
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T6327TubacinTubacin
Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.
价 格:¥电议型 号:T6327产 地:美洲
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T6329INO-1001INO-1001,INO1001,INO 1001
INO-1001 is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
价 格:¥电议型 号:T6329产 地:美洲
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T6330PI3Kδ-IN-2PI3Kδ-IN-2
PI3Kδ-IN-2 is a potent and selective inhibitor of PI3Kδ
价 格:¥电议型 号:T6330产 地:美洲
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T6331AST-1306 TsOHAST-1306 TsOH,Allitinib tosylate,AST-1306 (TsOH)
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.
价 格:¥电议型 号:T6331产 地:美洲
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T6332PevonedistatPevonedistat,MLN4924,
MLN4924 is an effective and specific small molecule NEDD8-activating enzyme (NAE) inhibitor (IC50: 4.7 nM).
价 格:¥电议型 号:T6332产 地:美洲
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T6335Tie2 kinase inhibitorTie2 kinase inhibitor
Tie2 kinase inhibitor, an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.
价 格:¥电议型 号:T6335产 地:美洲
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T6336AmonafideAmonafide,AS1413,NSC308847,AS1413
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
价 格:¥电议型 号:T6336产 地:美洲
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T6337RepSoxRepSox,SJN 2511,E-616452
RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.
价 格:¥电议型 号:T6337产 地:美洲
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T6339AG-14361AG-14361,AG14361,AG 14361
AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).
价 格:¥电议型 号:T6339产 地:美洲