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T74221ER degrader 2;化合物 ER degrader 2ER degrader 2
ER Degrader 2, a potent estrogen receptor (ER) degrader, plays a significant role in the estrogen signaling system, which is crucial for regulating cell growth, differentiation, and apoptosis. It holds promise for research in cancer diseases[1].
价 格:¥电议型 号:T74221产 地:中国大陆
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T74215EGFR-IN-22;化合物 EGFR-IN-22EGFR-IN-22
EGFR-IN-22 is a highly effective inhibitor targeting wild type EGFR and its mutant form, EGFR L858R/T790M/C797S, displaying IC50 values of 4.91 nM and 0.54 nM, respectively.
价 格:¥电议型 号:T74215产 地:中国大陆
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T74159ETX0462;化合物 ETX0462ETX0462
ETX0462 is a gram-negative chemotype antibiotic with potent in vitro and in vivo activity against Pseudomonas aeruginosa, all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia, and biothreat pathogens [1].
价 格:¥电议型 号:T74159产 地:中国大陆
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T74051Pyridinium bisretinoid A2E;化合物 Pyridinium bisretinoid A2EPyridinium bisretinoid A2E
Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis . Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species [1] [2] .
价 格:¥电议型 号:T74051产 地:中国大陆
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T73921Ep300/CREBBP-IN-2;化合物 Ep300/CREBBP-IN-2Ep300/CREBBP-IN-2
Ep300/CREBBP-IN-2 (Example 73), a powerful and orally bioavailable inhibitor targeting Ep300 and CREBBP, demonstrates IC50 values of 0.052 μM and 0.148 μM, respectively. This compound is employed in cancer research [1].
价 格:¥电议型 号:T73921产 地:中国大陆
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T72983eeAChE-IN-2;化合物 eeAChE-IN-2eeAChE-IN-2
eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.
价 格:¥电议型 号:T72983产 地:中国大陆
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T72765EphA2 agonist 2;化合物 EphA2 agonist 2EphA2 agonist 2
EphA2 agonist 2 (Lead compound) is a selective agonist targeting the EphA2 receptor, exhibiting antitumor properties and the ability to cross the blood-brain barrier (BBB).
价 格:¥电议型 号:T72765产 地:中国大陆
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T72164Enpp/Carbonic anhydrase-IN-2;化合物 Enpp/Carbonic anhydrase-IN-2Enpp/Carbonic anhydrase-IN-2
Enpp/Carbonic anhydrase-IN-2 is a potent Enpp and carbonic anhydrase inhibitor with IC 50 s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-2 induces Apoptosis [1] .
价 格:¥电议型 号:T72164产 地:中国大陆
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T72097Eleven-Nineteen-Leukemia Protein IN-2;化合物 Eleven-Nineteen-Leukemia Protein IN-2Eleven-Nineteen-Leuke
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].
价 格:¥电议型 号:T72097产 地:中国大陆
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T7189AMG9810化合物AMG9810(2E)-N-(2,3-二氢-1,4-苯并二噁英-6-基)-3-[4-(1,1-二甲基乙基)苯基]-2-丙酰胺
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively).
价 格:¥电议型 号:T7189产 地:中国大陆
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T71139EXP3892;化合物 EXP3892EXP3892
EXP3892 is an angiotensin II receptor antagonist.
价 格:¥电议型 号:T71139产 地:中国大陆
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T7062Ethambutol;化合物 T7062Ethambutol
Ethambutol is a bacteriostatic antimycobacterial agent obstructed the formation of cell wall by inhibiting arabinosyl transferases.
价 格:¥电议型 号:T7062产 地:中国大陆
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T70188ER-34122;化合物 ER-34122ER-34122
ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor, exhibits potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model.
价 格:¥电议型 号:T70188产 地:中国大陆
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T69806EGIS-8332;化合物 EGIS-8332EGIS-8332
EGIS-8332 is a potent and selective non-competitive AMPA receptor antagonist. EGIS-8332 inhibits AMPA/kainate ion channels and cell death. EGIS-8332 inhibited AMPA currents in rat cerebellar Purkinje cells and inhibited the AMPA- and quisqualate-induced excitotoxicity in primary cultures of telencephalon neurons (IC(50)=5.1-9.0 microM), in vitro. EGIS-8332 seems suitable for further development for the treatment of epilepsy, ischaemia and stroke based on its efficacy in a variety of experimenta
价 格:¥电议型 号:T69806产 地:中国大陆
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T69797ETX0282;化合物 ETX0282ETX0282
ETX0282 is an orally available, broad spectrum inhibitor of class A and C β-lactamases. Entasis is developing ETX0282 in combination with cefpodoxime proxetil, an orally available cephalosporin approved for treatment of a variety of bacterial infections.
价 格:¥电议型 号:T69797产 地:中国大陆
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T69787EF-7412;化合物 EF-7412EF-7412
EF-7412 is a ligand that is characterized as an antagonist in vivo in pre- and postsynaptic 5-HT(1A)R sites.
价 格:¥电议型 号:T69787产 地:中国大陆
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T69601ER272;化合物 ER272ER272
ER272 is a natural PKC activator, inducing hippocampal neurogenesis.
价 格:¥电议型 号:T69601产 地:中国大陆
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T69327E2072;化合物 E2072E2072
E2072 is a potent and selective thiol-based Glutamate Carboxypeptidase II (GCP-II) inhibitor.
价 格:¥电议型 号:T69327产 地:中国大陆
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T67946EP2 receptor antagonist-2;EP2受体拮抗剂2EP2 receptor antagonist-2
EP2 receptor antagonist-2 (CID891729) is a compound that not only serves as an antagonist to the EP2 receptor, blocking its activation by PGE2, but also reduces lactate dehydrogenase (LDH) release triggered by N-methyl-D-aspartate (NMDA).
价 格:¥电议型 号:T67946产 地:中国大陆
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T67699LALK/ROS1 inhibitor 2e HCL;化合物 ALK/ROS1 inhibitor 2e HCL(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl
ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
价 格:¥电议型 号:T67699L产 地:中国大陆